| Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-β JG Abreu, NI Ketpura, B Reversade, EM De Robertis Nature cell biology 4 (8), 599-604, 2002 | 1169 | 2002 |
| Amyloid-β binds to the extracellular cysteine-rich domain of Frizzled and inhibits Wnt/β-catenin signaling MH Magdesian, MMVF Carvalho, FA Mendes, LM Saraiva, MA Juliano, ... Journal of Biological Chemistry 283 (14), 9359-9368, 2008 | 318 | 2008 |
| Tet3 CXXC domain and dioxygenase activity cooperatively regulate key genes for Xenopus eye and neural development Y Xu, C Xu, A Kato, W Tempel, JG Abreu, C Bian, Y Hu, D Hu, B Zhao, ... Cell 151 (6), 1200-1213, 2012 | 310 | 2012 |
| Inhibition of GSK3 phosphorylation of β-catenin via phosphorylated PPPSPXS motifs of Wnt coreceptor LRP6 G Wu, H Huang, JG Abreu, X He PloS one 4 (3), e4926, 2009 | 266 | 2009 |
| Wnt stabilization of β-catenin reveals principles for morphogen receptor-scaffold assemblies SE Kim, H Huang, M Zhao, X Zhang, A Zhang, MV Semonov, ... Science 340 (6134), 867-870, 2013 | 245 | 2013 |
| Complementary hydropathy identifies a cellular prion protein receptor VR Martins, E Graner, J Garcia-Abreu, SJ De Souza, AF Mercadante, ... Nature medicine 3 (12), 1376-1382, 1997 | 230 | 1997 |
| Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Aβ oligomerization FG De Felice, MNN Vieira, LM Saraiva, JD Figueroa‐Villar, ... The FASEB journal 18 (12), 1366-1372, 2004 | 228 | 2004 |
| Chordin-like CR domains and the regulation of evolutionarily conserved extracellular signaling systems JG Abreu, C Coffinier, J Larraın, M Oelgeschläger, EM De Robertis Gene 287 (1-2), 39-47, 2002 | 205 | 2002 |
| Gap-junctional coupling between neurons and astrocytes in primary central nervous system cultures MM FROes, AHP Correia, J Garcia-Abreu, DC Spray, ... Proceedings of the National Academy of Sciences 96 (13), 7541-7546, 1999 | 192 | 1999 |
| Notum is required for neural and head induction via Wnt deacylation, oxidation, and inactivation X Zhang, SM Cheong, NG Amado, AH Reis, BT MacDonald, M Zebisch, ... Developmental cell 32 (6), 719-730, 2015 | 184 | 2015 |
| Inhibition of Alzheimer's disease β‐amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: implications for Alzheimer's therapy FG De Felice, JC Houzel, J Garcia-Abreu, PRF Louzada Jr, RC Afonso, ... The FASEB Journal 15 (7), 1297-1299, 2001 | 165 | 2001 |
| Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation X Zhang, JG Abreu, C Yokota, BT MacDonald, S Singh, KLA Coburn, ... Cell 149 (7), 1565-1577, 2012 | 147 | 2012 |
| Flavonoids: potential Wnt/beta-catenin signaling modulators in cancer NG Amado, BF Fonseca, DM Cerqueira, VM Neto, JG Abreu Life sciences 89 (15-16), 545-554, 2011 | 132 | 2011 |
| Isoquercitrin suppresses colon cancer cell growth in vitro by targeting the Wnt/β-catenin signaling pathway NG Amado, D Predes, BF Fonseca, DM Cerqueira, AH Reis, ... Journal of Biological Chemistry 289 (51), 35456-35467, 2014 | 110 | 2014 |
| Isoquercitrin isolated from Hyptis fasciculata reduces glioblastoma cell proliferation and changes β-catenin cellular localization NG Amado, DM Cerqueira, FS Menezes, JFM da Silva, VM Neto, ... Anti-cancer drugs 20 (7), 543-552, 2009 | 107 | 2009 |
| Complexity of the Wnt/β‑catenin pathway: Searching for an activation model GG Tortelote, RR Reis, F de Almeida Mendes, JG Abreu Cellular signalling 40, 30-43, 2017 | 94 | 2017 |
| Blocking the Wnt pathway, a unifying mechanism for an angiogenic inhibitor in the serine proteinase inhibitor family B Zhang, JG Abreu, K Zhou, Y Chen, Y Hu, T Zhou, X He, J Ma Proceedings of the National Academy of Sciences 107 (15), 6900-6905, 2010 | 92 | 2010 |
| Neurons induce GFAP gene promoter of cultured astrocytes from transgenic mice F Carvalho, A Gomes, J Garcia‐Abreu, M Galou, D Paulin, V Moura Neto Glia 26 (2), 97-108, 1999 | 92 | 1999 |
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| Flavonoids and Wnt/β-catenin signaling: potential role in colorectal cancer therapies NG Amado, D Predes, MM Moreno, IO Carvalho, FA Mendes, JG Abreu International journal of molecular sciences 15 (7), 12094-12106, 2014 | 88 | 2014 |
