Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 195 | 2013 |
The bile acid deoxycholic acid (DCA) at neutral pH activates NF-κB and induces IL-8 expression in oesophageal cells in vitro GJS Jenkins, K Harries, SH Doak, A Wilmes, AP Griffiths, JN Baxter, ... Carcinogenesis 25 (3), 317-323, 2004 | 168 | 2004 |
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 141 | 2015 |
The molecular and cellular aspects of arthritis due to alphavirus infections: lesson learned from Ross River virus NE Rulli, J Melton, A Wilmes, G Ewart, S Mahalingam Annals of the New York Academy of Sciences 1102 (1), 96-108, 2007 | 108 | 2007 |
Identification and dissection of the Nrf2 mediated oxidative stress pathway in human renal proximal tubule toxicity A Wilmes, D Crean, S Aydin, W Pfaller, P Jennings, MO Leonard Toxicology In Vitro 25 (3), 613-622, 2011 | 102 | 2011 |
Peloruside A synergizes with other microtubule stabilizing agents in cultured cancer cell lines A Wilmes, K Bargh, C Kelly, PT Northcote, JH Miller Molecular pharmaceutics 4 (2), 269-280, 2007 | 100 | 2007 |
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ... Toxicology in Vitro 25 (8), 1855-1862, 2011 | 93 | 2011 |
Delineation of the key aspects in the regulation of epithelial monolayer formation L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ... Molecular and cellular biology 33 (13), 2535-2550, 2013 | 91 | 2013 |
Ross River virus: molecular and cellular aspects of disease pathogenesis NE Rulli, A Suhrbier, L Hueston, MT Heise, D Tupanceska, A Zaid, ... Pharmacology & therapeutics 107 (3), 329-342, 2005 | 74 | 2005 |
Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: a transcriptomic study L Aschauer, A Limonciel, A Wilmes, S Stanzel, A Kopp-Schneider, ... Toxicology in Vitro 30 (1), 106-116, 2015 | 68 | 2015 |
Peloruside B, a potent antitumor macrolide from the New Zealand marine sponge Mycale hentscheli: isolation, structure, total synthesis, and bioactivity AJ Singh, CX Xu, X Xu, LM West, A Wilmes, A Chan, E Hamel, JH Miller, ... The Journal of organic chemistry 75 (1), 2-10, 2010 | 64 | 2010 |
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model P Jennings, C Weiland, A Limonciel, KM Bloch, R Radford, L Aschauer, ... Archives of toxicology 86, 571-589, 2012 | 55 | 2012 |
Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq A Limonciel, G Ates, G Carta, A Wilmes, M Watzele, PJ Shepard, ... Archives of toxicology 92, 2517-2531, 2018 | 54 | 2018 |
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells A Limonciel, A Wilmes, L Aschauer, R Radford, KM Bloch, T McMorrow, ... Archives of toxicology 86, 1741-1751, 2012 | 53 | 2012 |
Differentiation of human iPSCs into functional podocytes C Rauch, E Feifel, G Kern, C Murphy, F Meier, W Parson, M Beilmann, ... PloS one 13 (9), e0203869, 2018 | 52 | 2018 |
Peloruside-and laulimalide-resistant human ovarian carcinoma cells have βI-tubulin mutations and altered expression of βII-and βIII-tubulin isotypes A Kanakkanthara, A Wilmes, A O'Brate, D Escuin, A Chan, A Gjyrezi, ... Molecular cancer therapeutics 10 (8), 1419-1429, 2011 | 49 | 2011 |
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing D Crean, P Bellwon, L Aschauer, A Limonciel, K Moenks, P Hewitt, ... Toxicology in Vitro 30 (1), 128-137, 2015 | 44 | 2015 |
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods A Krebs, BMA van Vugt-Lussenburg, T Waldmann, W Albrecht, J Boei, ... Archives of Toxicology 94, 2435-2461, 2020 | 41 | 2020 |
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing A Limonciel, K Moenks, S Stanzel, GL Truisi, C Parmentier, L Aschauer, ... Toxicology in Vitro 30 (1), 7-18, 2015 | 38 | 2015 |
Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel A Wilmes, L Aschauer, A Limonciel, W Pfaller, P Jennings Toxicology and applied pharmacology 279 (2), 163-172, 2014 | 38 | 2014 |