Targeting tumor metabolism for cancer treatment: is pyruvate dehydrogenase kinases (PDKs) a viable anticancer target? W Zhang, SL Zhang, X Hu, KY Tam International journal of biological sciences 11 (12), 1390, 2015 | 182 | 2015 |
Synthesis and biological evaluation of α-triazolyl chalcones as a new type of potential antimicrobial agents and their interaction with calf thymus DNA and human serum albumin BT Yin, CY Yan, XM Peng, SL Zhang, S Rasheed, RX Geng, CH Zhou European journal of medicinal chemistry 71, 148-159, 2014 | 168 | 2014 |
Synthesis and biological evaluation of novel benzimidazole derivatives and their binding behavior with bovine serum albumin SL Zhang, GLV Damu, L Zhang, RX Geng, CH Zhou European journal of medicinal chemistry 55, 164-175, 2012 | 125 | 2012 |
Discovery of membrane active benzimidazole quinolones-based topoisomerase inhibitors as potential DNA-binding antimicrobial agents L Zhang, D Addla, J Ponmani, A Wang, D Xie, YN Wang, SL Zhang, ... European journal of medicinal chemistry 111, 160-182, 2016 | 119 | 2016 |
Synthesis and biological evaluation of a class of quinolone triazoles as potential antimicrobial agents and their interactions with calf thymus DNA SF Cui, Y Ren, SL Zhang, XM Peng, GLV Damu, RX Geng, CH Zhou Bioorganic & medicinal chemistry letters 23 (11), 3267-3272, 2013 | 109 | 2013 |
Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation LL Wang, N Battini, RRY Bheemanaboina, SL Zhang, CH Zhou European journal of medicinal chemistry 167, 105-123, 2019 | 98 | 2019 |
Engineering of a dual-recognition ratiometric fluorescent nanosensor with a remarkably large stokes shift for accurate tracking of pathogenic bacteria at the single-cell level Y Shen, T Wu, Y Zhang, N Ling, L Zheng, SL Zhang, Y Sun, X Wang, Y Ye Analytical Chemistry 92 (19), 13396-13404, 2020 | 90 | 2020 |
A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and … LL Wang, N Battini, RRY Bheemanaboina, MF Ansari, JP Chen, YP Xie, ... European Journal of Medicinal Chemistry 179, 166-181, 2019 | 87 | 2019 |
Development of pyruvate dehydrogenase kinase inhibitors in medicinal chemistry with particular emphasis as anticancer agents SL Zhang, X Hu, W Zhang, H Yao, KY Tam Drug discovery today 20 (9), 1112-1119, 2015 | 83 | 2015 |
Novel berberine triazoles: synthesis, antimicrobial evaluation and competitive interactions with metal ions to human serum albumin SL Zhang, JJ Chang, GLV Damu, B Fang, XD Zhou, RX Geng, CH Zhou Bioorganic & medicinal chemistry letters 23 (4), 1008-1012, 2013 | 83 | 2013 |
Synthesis and bioactive evaluation of novel hybrids of metronidazole and berberine as new type of antimicrobial agents and their transportation behavior by human serum albumin L Zhang, JJ Chang, SL Zhang, GLV Damu, RX Geng, CH Zhou Bioorganic & medicinal chemistry 21 (14), 4158-4169, 2013 | 72 | 2013 |
Indole-nitroimidazole conjugates as efficient manipulators to decrease the genes expression of methicillin-resistant Staphylococcus aureus ZZ Li, VKR Tangadanchu, N Battini, RRY Bheemanaboina, ZL Zang, ... European Journal of Medicinal Chemistry 179, 723-735, 2019 | 69 | 2019 |
Targeting cancer metabolism to develop human lactate dehydrogenase (hLDH) 5 inhibitors SL Zhang, Y He, KY Tam Drug discovery today 23 (7), 1407-1415, 2018 | 61 | 2018 |
Quinazolinone Azolyl Ethanols: Potential Lead Antimicrobial Agents with Dual Action Modes Targeting Methicillin-Resistant Staphylococcus Aureus DNA XM Peng, LP Peng, S Li, SR Avula, VK Kannekanti, SL Zhang, KY Tam, ... Future Medicinal Chemistry 8 (16), 1927-1940, 2016 | 60 | 2016 |
Berberine azoles as antimicrobial agents: synthesis, biological evaluation and their interactions with human serum albumin SL Zhang, JJ Chang, GLV Damu, RX Geng, CH Zhou MedChemComm 4 (5), 839-846, 2013 | 58 | 2013 |
Unexpected discovery of dichloroacetate derived adenosine triphosphate competitors targeting pyruvate dehydrogenase kinase to inhibit cancer proliferation SL Zhang, X Hu, W Zhang, KY Tam Journal of medicinal chemistry 59 (7), 3562-3568, 2016 | 56 | 2016 |
Nucleolin-targeted ratiometric fluorescent carbon dots with a remarkably large emission wavelength shift for precise imaging of cathepsin B in living cancer cells Y Shen, T Wu, Y Wang, SL Zhang, X Zhao, HY Chen, JJ Xu Analytical Chemistry 93 (8), 4042-4050, 2021 | 55 | 2021 |
Design, synthesis, and antibacterial evaluation of novel azolylthioether quinolones as MRSA DNA intercalators L Zhang, KV Kumar, S Rasheed, SL Zhang, RX Geng, CH Zhou MedChemComm 6 (7), 1303-1310, 2015 | 54 | 2015 |
Organocatalytic Asymmetric One‐Step Desymmetrizing Dearomatization Reaction of Indoles: Development and Bioactivity Evaluation L Peng, D Xu, X Yang, J Tang, X Feng, SL Zhang, H Yan Angewandte Chemie International Edition 58 (1), 216-220, 2019 | 52 | 2019 |
Novel carbazole-oxadiazoles as potential Staphylococcus aureus germicides YP Xie, MF Ansari, SL Zhang, CH Zhou Pesticide Biochemistry and Physiology 175, 104849, 2021 | 50 | 2021 |