Building a global alliance of biofoundries N Hillson, M Caddick, Y Cai, JA Carrasco, MW Chang, NC Curach, ... Nature communications 10 (1), 2040, 2019 | 267 | 2019 |
Engineered commensal microbes for diet-mediated colorectal-cancer chemoprevention CL Ho, HQ Tan, KJ Chua, A Kang, KH Lim, KL Ling, WS Yew, YS Lee, ... Nature Biomedical Engineering 2 (1), 27-37, 2018 | 224 | 2018 |
Development of quorum-based anti-virulence therapeutics targeting Gram-negative bacterial pathogens SB Tay, WS Yew International journal of molecular sciences 14 (8), 16570-16599, 2013 | 151 | 2013 |
Utilization of l-Ascorbate by Escherichia coli K-12: Assignments of Functions to Products of the yjf-sga and yia-sgb Operons WS Yew, JA Gerlt Journal of bacteriology 184 (1), 302-306, 2002 | 133 | 2002 |
Enhancing gold recovery from electronic waste via lixiviant metabolic engineering in Chromobacterium violaceum SB Tay, G Natarajan, MNA Rahim, HT Tan, MCM Chung, YP Ting, ... Scientific reports 3 (1), 2236, 2013 | 131 | 2013 |
Disruption of biofilm formation by the human pathogen Acinetobacter baumannii using engineered quorum-quenching lactonases JY Chow, Y Yang, SB Tay, KL Chua, WS Yew Antimicrobial agents and chemotherapy 58 (3), 1802-1805, 2014 | 114 | 2014 |
Evolution of enzymatic activities in the enolase superfamily: L-fuconate dehydratase from Xanthomonas campestris WS Yew, AA Fedorov, EV Fedorov, JF Rakus, RW Pierce, SC Almo, ... Biochemistry 45 (49), 14582-14597, 2006 | 111 | 2006 |
Directed evolution of a thermostable quorum-quenching lactonase from the amidohydrolase superfamily JY Chow, B Xue, KH Lee, A Tung, L Wu, RC Robinson, WS Yew Journal of biological chemistry 285 (52), 40911-40920, 2010 | 102 | 2010 |
Engineering a riboswitch-based genetic platform for the self-directed evolution of acid-tolerant phenotypes HL Pham, A Wong, N Chua, WS Teo, WS Yew, MW Chang Nature communications 8 (1), 411, 2017 | 91 | 2017 |
Exploiting the biosynthetic potential of type III polyketide synthases YP Lim, MK Go, WS Yew Molecules 21 (6), 806, 2016 | 90 | 2016 |
Directed Evolution of a Quorum-Quenching Lactonase from Mycobacterium avium subsp. paratuberculosis K-10 in the Amidohydrolase Superfamily JY Chow, L Wu, WS Yew Biochemistry 48 (20), 4344-4353, 2009 | 84 | 2009 |
COVID-19 endocrinopathy with hindsight from SARS N Kothandaraman, A Rengaraj, B Xue, WS Yew, SS Velan, N Karnani, ... American Journal of Physiology-Endocrinology and Metabolism 320 (1), E139-E150, 2021 | 83 | 2021 |
Homologous (β/α)8-Barrel Enzymes That Catalyze Unrelated Reactions: Orotidine 5‘-Monophosphate Decarboxylase and 3-Keto-l-Gulonate 6-Phosphate Decarboxylase … E Wise, WS Yew, PC Babbitt, JA Gerlt, I Rayment Biochemistry 41 (12), 3861-3869, 2002 | 81 | 2002 |
Evolution of enzymatic activities in the enolase superfamily: N-succinylamino acid racemase and a new pathway for the irreversible conversion of D-to L-amino acids A Sakai, DF Xiang, C Xu, L Song, WS Yew, FM Raushel, JA Gerlt Biochemistry 45 (14), 4455-4462, 2006 | 77 | 2006 |
Reprogramming Probiotic Lactobacillus reuteri as a Biosensor for Staphylococcus aureus Derived AIP-I Detection D Lubkowicz, CL Ho, IY Hwang, WS Yew, YS Lee, MW Chang ACS synthetic biology 7 (5), 1229-1237, 2018 | 69 | 2018 |
Site-directed mutagenesis on human cystathionine-γ-lyase reveals insights into the modulation of H2S production S Huang, JH Chua, WS Yew, J Sivaraman, PK Moore, CH Tan, LW Deng Journal of molecular biology 396 (3), 708-718, 2010 | 66 | 2010 |
Evolution of Enzymatic Activities in the Orotidine 5‘-Monophosphate Decarboxylase Suprafamily: Enhancing the Promiscuous d-arabino-Hex-3-ulose 6-Phosphate … WS Yew, J Akana, EL Wise, I Rayment, JA Gerlt Biochemistry 44 (6), 1807-1815, 2005 | 56 | 2005 |
The divergent immunomodulatory effects of short chain fatty acids and medium chain fatty acids QH Sam, H Ling, WS Yew, Z Tan, S Ravikumar, MW Chang, LYA Chai International journal of molecular sciences 22 (12), 6453, 2021 | 53 | 2021 |
Immunomodulation as therapy for fungal infection: are we closer? QH Sam, WS Yew, CJ Seneviratne, MW Chang, LYA Chai Frontiers in microbiology 9, 357398, 2018 | 51 | 2018 |
Reprogrammable microbial cell-based therapeutics against antibiotic-resistant bacteria IY Hwang, E Koh, HR Kim, WS Yew, MW Chang Drug Resistance Updates 27, 59-71, 2016 | 48 | 2016 |