| Downregulation of EZH2 decreases growth of estrogen receptor-negative invasive breast carcinoma and requires BRCA1 ME Gonzalez, X Li, K Toy, M DuPrie, AC Ventura, M Banerjee, ... Oncogene 28 (6), 843-853, 2009 | 243 | 2009 |
| Histone methyltransferase EZH2 induces Akt-dependent genomic instability and BRCA1 inhibition in breast cancer ME Gonzalez, ML DuPrie, H Krueger, SD Merajver, AC Ventura, KA Toy, ... Cancer research 71 (6), 2360-2370, 2011 | 126 | 2011 |
| A hidden feedback in signaling cascades is revealed AC Ventura, JA Sepulchre, SD Merajver PLoS computational biology 4 (3), e1000041, 2008 | 117 | 2008 |
| Signaling properties of a covalent modification cycle are altered by a downstream target AC Ventura, P Jiang, L Van Wassenhove, D Del Vecchio, SD Merajver, ... Proceedings of the National Academy of Sciences 107 (22), 10032-10037, 2010 | 111 | 2010 |
| Load-induced modulation of signal transduction networks P Jiang, AC Ventura, ED Sontag, SD Merajver, AJ Ninfa, D Del Vecchio Science signaling 4 (194), ra67-ra67, 2011 | 89 | 2011 |
| p38γ promotes breast cancer cell motility and metastasis through regulation of RhoC GTPase, cytoskeletal architecture, and a novel leading edge behavior DT Rosenthal, H Iyer, S Escudero, L Bao, Z Wu, AC Ventura, CG Kleer, ... Cancer research 71 (20), 6338-6349, 2011 | 73 | 2011 |
| Kinase inhibitors can produce off-target effects and activate linked pathways by retroactivity ML Wynn, AC Ventura, JA Sepulchre, HJ García, SD Merajver BMC systems biology 5, 1-15, 2011 | 57 | 2011 |
| Multisite phosphorylation provides an effective and flexible mechanism for switch-like protein degradation SM Varedi K, AC Ventura, SD Merajver, XN Lin PLoS One 5 (12), e14029, 2010 | 51 | 2010 |
| Utilization of extracellular information before ligand-receptor binding reaches equilibrium expands and shifts the input dynamic range AC Ventura, A Bush, G Vasen, MA Goldín, B Burkinshaw, N Bhattacharjee, ... Proceedings of the National Academy of Sciences 111 (37), E3860-E3869, 2014 | 48 | 2014 |
| Long signaling cascades tend to attenuate retroactivity HR Ossareh, AC Ventura, SD Merajver, D Del Vecchio Biophysical journal 100 (7), 1617-1626, 2011 | 48 | 2011 |
| On the role of cell signaling models in cancer research AC Ventura, TL Jackson, SD Merajver Cancer research 69 (2), 400-402, 2009 | 43 | 2009 |
| Cell cycle dynamics of mouse embryonic stem cells in the ground state and during transition to formative pluripotency A Waisman, F Sevlever, M Elías Costa, MS Cosentino, SG Miriuka, ... Scientific reports 9 (1), 8051, 2019 | 40 | 2019 |
| Quantifying calcium fluxes underlying calcium puffs in Xenopus laevis oocytes L Bruno, G Solovey, AC Ventura, S Dargan, SP Dawson Cell calcium 47 (3), 273-286, 2010 | 37 | 2010 |
| Genetic determinants of aggressive breast cancer AC Ventura, SD Merajver Annu. Rev. Med. 59 (1), 199-212, 2008 | 31 | 2008 |
| Ultrasensitivity in signaling cascades revisited: Linking local and global ultrasensitivity estimations E Altszyler, AC Ventura, A Colman-Lerner, A Chernomoretz PLoS One 12 (6), e0180083, 2017 | 30 | 2017 |
| Preclinical development of a bifunctional cancer cell homing, PKCε inhibitory peptide for the treatment of head and neck cancer L Bao, MA Gorin, M Zhang, AC Ventura, WC Pomerantz, SD Merajver, ... Cancer research 69 (14), 5829-5834, 2009 | 30 | 2009 |
| Simple data-driven models of intracellular calcium dynamics with predictive power AC Ventura, L Bruno, SP Dawson Physical Review E—Statistical, Nonlinear, and Soft Matter Physics 74 (1 …, 2006 | 29 | 2006 |
| A model-independent algorithm to derive Ca2+ fluxes underlying local cytosolic Ca2+ transients AC Ventura, L Bruno, A Demuro, I Parker, SP Dawson Biophysical journal 88 (4), 2403-2421, 2005 | 25 | 2005 |
| Signaling cascades transmit information downstream and upstream but unlikely simultaneously S Catozzi, JP Di-Bella, AC Ventura, JA Sepulchre BMC Systems Biology 10, 1-20, 2016 | 18 | 2016 |
| Intrinsic feedbacks in MAPK signaling cascades lead to bistability and oscillations JA Sepulchre, AC Ventura Acta biotheoretica 61, 59-78, 2013 | 17 | 2013 |
