Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods C Wu, Y Liu, Y Yang, P Zhang, W Zhong, Y Wang, Q Wang, Y Xu, M Li, ... Acta Pharmaceutica Sinica B 10 (5), 766-788, 2020 | 2510 | 2020 |
Structural insight into the ion-exchange mechanism of the sodium/calcium exchanger J Liao, H Li, W Zeng, DB Sauer, R Belmares, Y Jiang Science 335 (6069), 686-690, 2012 | 298 | 2012 |
Furin: a potential therapeutic target for COVID-19 C Wu, M Zheng, Y Yang, X Gu, K Yang, M Li, Y Liu, Q Zhang, P Zhang, ... Iscience 23 (10), 2020 | 162 | 2020 |
Structural and biochemical studies of TIGAR (TP53-induced glycolysis and apoptosis regulator) H Li, G Jogl Journal of Biological Chemistry 284 (3), 1748-1754, 2009 | 139 | 2009 |
Phomopsterones A and B, Two Functionalized Ergostane-Type Steroids from the Endophytic Fungus Phomopsis sp. TJ507A Z Hu, Y Wu, S Xie, W Sun, Y Guo, XN Li, J Liu, H Li, J Wang, Z Luo, Y Xue, ... Organic letters 19 (1), 258-261, 2017 | 113 | 2017 |
Rational design and synthesis of novel dual PROTACs for simultaneous degradation of EGFR and PARP M Zheng, J Huo, X Gu, Y Wang, C Wu, Q Zhang, W Wang, Y Liu, Y Liu, ... Journal of Medicinal Chemistry 64 (11), 7839-7852, 2021 | 111 | 2021 |
Benserazide, a dopadecarboxylase inhibitor, suppresses tumor growth by targeting hexokinase 2 W Li, M Zheng, S Wu, S Gao, M Yang, Z Li, Q Min, W Sun, L Chen, ... Journal of Experimental & Clinical Cancer Research 36, 1-12, 2017 | 105 | 2017 |
Drug discovery is an eternal challenge for the biomedical sciences H Li, W Wei, H Xu Acta Materia Medica 1 (1), 1-3, 2022 | 101 | 2022 |
LncRNA-mediated DNA methylation: an emerging mechanism in cancer and beyond W Huang, H Li, Q Yu, W Xiao, DO Wang Journal of Experimental & Clinical Cancer Research 41 (1), 100, 2022 | 98 | 2022 |
Triterpenoids from Ganoderma lucidum and Their Potential Anti-inflammatory Effects YL Wu, F Han, SS Luan, R Ai, P Zhang, H Li, LX Chen Journal of agricultural and food chemistry 67 (18), 5147-5158, 2019 | 95 | 2019 |
Asperterpenes A and B, two unprecedented meroterpenoids from Aspergillus terreus with BACE1 inhibitory activities C Qi, J Bao, J Wang, H Zhu, Y Xue, X Wang, H Li, W Sun, W Gao, Y Lai, ... Chemical Science 7 (10), 6563-6572, 2016 | 88 | 2016 |
Progress in the discovery of naturally occurring anti-diabetic drugs and in the identification of their molecular targets JH He, LX Chen, H Li Fitoterapia 134, 270-289, 2019 | 87 | 2019 |
Crystal structure of the zinc-binding transport protein ZnuA from Escherichia coli reveals an unexpected variation in metal coordination H Li, G Jogl Journal of molecular biology 368 (5), 1358-1366, 2007 | 80 | 2007 |
Filicinic Acid Based Meroterpenoids with Anti-Epstein–Barr Virus Activities from Hypericum japonicum L Hu, Y Zhang, H Zhu, J Liu, H Li, XN Li, W Sun, J Zeng, Y Xue, Y Zhang Organic letters 18 (9), 2272-2275, 2016 | 72 | 2016 |
Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase X Zeng, L Liu, M Zheng, H Sun, J Xiao, T Lu, G Huang, P Chen, J Zhang, ... Oncotarget 7 (16), 22460, 2016 | 63 | 2016 |
Novel selective hexokinase 2 inhibitor Benitrobenrazide blocks cancer cells growth by targeting glycolysis M Zheng, C Wu, K Yang, Y Yang, Y Liu, S Gao, Q Wang, C Li, L Chen, ... Pharmacological research 164, 105367, 2021 | 62 | 2021 |
Bcl-XL: a multifunctional anti-apoptotic protein M Li, D Wang, J He, L Chen, H Li Pharmacological research 151, 104547, 2020 | 61 | 2020 |
New natural inhibitors of hexokinase 2 (HK2): Steroids from Ganoderma sinense F Bao, K Yang, C Wu, S Gao, P Wang, L Chen, H Li Fitoterapia 125, 123-129, 2018 | 61 | 2018 |
Discovery of metal-based complexes as promising antimicrobial agents J Liang, D Sun, Y Yang, M Li, H Li, L Chen European Journal of Medicinal Chemistry 224, 113696, 2021 | 60 | 2021 |
Diterpenoids from the genus Euphorbia: Structure and biological activity (2013–2019) Y Xu, P Tang, M Zhu, Y Wang, D Sun, H Li, L Chen Phytochemistry 190, 112846, 2021 | 56 | 2021 |