Eleven grand challenges in single-cell data science D Lähnemann, J Köster, E Szczurek, DJ McCarthy, SC Hicks, ... Genome biology 21, 1-35, 2020 | 997 | 2020 |
Whole-genome sequence variation, population structure and demographic history of the Dutch population Nature genetics 46 (8), 818-825, 2014 | 722 | 2014 |
Genome-wide patterns and properties of de novo mutations in humans LC Francioli, PP Polak, A Koren, A Menelaou, S Chun, I Renkens, ... Nature genetics 47 (7), 822-826, 2015 | 412 | 2015 |
WhatsHap: Weighted Haplotype Assembly for Future-Generation Sequencing Reads M Patterson, T Marschall, N Pisanti, L Van Iersel, L Stougie, GW Klau, ... Journal of Computational Biology 22 (6), 498-509, 2015 | 358 | 2015 |
Using hidden Markov models to analyze gene expression time course data A Schliep, A Schönhuth, C Steinhoff Bioinformatics 19 (suppl_1), i255-i263, 2003 | 342 | 2003 |
Computational pan-genomics: status, promises and challenges Briefings in bioinformatics 19 (1), 118-135, 2018 | 337 | 2018 |
WhatsHap: fast and accurate read-based phasing M Martin, M Patterson, S Garg, S O Fischer, N Pisanti, GW Klau, ... BioRxiv, 085050, 2016 | 262 | 2016 |
Characteristics of de novo structural changes in the human genome WP Kloosterman, LC Francioli, F Hormozdiari, T Marschall, JY Hehir-Kwa, ... Genome research 25 (6), 792-801, 2015 | 153 | 2015 |
Improved imputation quality of low-frequency and rare variants in European samples using the ‘Genome of The Netherlands’ P Deelen, A Menelaou, EM Van Leeuwen, A Kanterakis, F Van Dijk, ... European Journal of Human Genetics 22 (11), 1321-1326, 2014 | 125 | 2014 |
Viral quasispecies assembly via maximal clique enumeration. A Töpfer, T Marschall, RA Bull, F Luciani, A Schönhuth, N Beerenwinkel PLoS Computational Biology 10 (3), e1003515, 2014 | 121 | 2014 |
ProClust: improved clustering of protein sequences with an extended graph-based approach P Pipenbacher, A Schliep, S Schneckener, A Schönhuth, D Schomburg, ... Bioinformatics 18 (suppl_2), S182-S191, 2002 | 119 | 2002 |
CLEVER: Clique-Enumerating Variant Finder T Marschall, I Costa, S Canzar, M Bauer, G Klau, A Schliep, A Schönhuth Bioinformatics 28 (22), 2875-2882, 2012 | 110 | 2012 |
De novo assembly of viral quasispecies using overlap graphs JA Baaijens, AZ El Aabidine, E Rivals, A Schönhuth Genome research 27 (5), 835-848, 2017 | 108 | 2017 |
A high-quality human reference panel reveals the complexity and distribution of genomic structural variants JY Hehir-Kwa, T Marschall, WP Kloosterman, LC Francioli, JA Baaijens, ... Nature communications 7 (1), 12989, 2016 | 108 | 2016 |
Population-specific genotype imputations using minimac or IMPUTE2 EM Van Leeuwen, A Kanterakis, P Deelen, MV Kattenberg, PE Slagboom, ... Nature protocols 10 (9), 1285-1296, 2015 | 100 | 2015 |
Analyzing gene expression time-courses A Schliep, IG Costa, C Steinhoff, A Schonhuth IEEE/ACM Transactions on computational biology and bioinformatics 2 (3), 179-193, 2005 | 97 | 2005 |
Discovering motifs that induce sequencing errors M Allhoff, A Schönhuth, M Martin, IG Costa, S Rahmann, T Marschall BMC bioinformatics 14, 1-10, 2013 | 84 | 2013 |
Leveraging distant relatedness to quantify human mutation and gene-conversion rates PF Palamara, LC Francioli, PR Wilton, G Genovese, A Gusev, ... The American Journal of Human Genetics 97 (6), 775-789, 2015 | 78 | 2015 |
Inferring cancer subnetwork markers using density-constrained biclustering P Dao, R Colak, R Salari, F Moser, E Davicioni, A Schönhuth, M Ester Bioinformatics 26 (18), i625-i631, 2010 | 75 | 2010 |
Automatic discovery of 100-miRNA signature for cancer classification using ensemble feature selection A Lopez-Rincon, M Martinez-Archundia, GU Martinez-Ruiz, A Schoenhuth, ... BMC bioinformatics 20, 1-17, 2019 | 71 | 2019 |