HPLC-based quantification of bacterial housekeeping nucleotides and alarmone messengers ppGpp and pppGpp V Varik, SRA Oliveira, V Hauryliuk, T Tenson Scientific reports 7 (1), 11022, 2017 | 101* | 2017 |
Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to β-Lactams P Kudrin, V Varik, SRA Oliveira, J Beljantseva, T Del Peso Santos, ... Antimicrobial agents and chemotherapy 61 (4), 10.1128/aac. 02173-16, 2017 | 61 | 2017 |
The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA P Kudrin, I Dzhygyr, K Ishiguro, J Beljantseva, E Maksimova, SRA Oliveira, ... Nucleic acids research 46 (4), 1973-1983, 2018 | 50 | 2018 |
Phenotypic heterogeneity enables uropathogenic Escherichia coli to evade killing by antibiotics and serum complement M Putrinš, K Kogermann, E Lukk, M Lippus, V Varik, T Tenson Infection and Immunity 83 (3), 1056-1067, 2015 | 44 | 2015 |
Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor J Beljantseva, P Kudrin, S Jimmy, M Ehn, R Pohl, V Varik, Y Tozawa, ... Scientific Reports 7 (1), 41839, 2017 | 35 | 2017 |
Composition of the outgrowth medium modulates wake-up kinetics and ampicillin sensitivity of stringent and relaxed Escherichia coli V Varik, SRA Oliveira, V Hauryliuk, T Tenson Scientific reports 6 (1), 22308, 2016 | 33 | 2016 |
Auxotrophy-based High Throughput Screening assay for the identification of Bacillus subtilis stringent response inhibitors L Andresen, V Varik, Y Tozawa, S Jimmy, S Lindberg, T Tenson, ... Scientific Reports 6 (1), 35824, 2016 | 25 | 2016 |
Evaluation of the characteristics of leucyl-tRNA synthetase (LeuRS) inhibitor AN3365 in combination with different antibiotic classes CG Monteferrante, A Jirgensons, V Varik, V Hauryliuk, WHF Goessens, ... European Journal of Clinical Microbiology & Infectious Diseases 35, 1857-1864, 2016 | 14 | 2016 |
Systematic analysis of drug combinations against Gram-positive bacteria E Cacace, V Kim, V Varik, M Knopp, M Tietgen, A Brauer-Nikonow, ... Nature Microbiology 8 (11), 2196-2212, 2023 | 11 | 2023 |
Systematic mapping of antibiotic cross-resistance and collateral sensitivity with chemical genetics N Sakenova, E Cacace, A Orakov, F Huber, V Varik, G Kritikos, J Michiels, ... bioarXiv, 2024 | | 2024 |
Uncovering nitroxoline activity spectrum, mode of action and resistance across Gram-negative bacteria E Cacace, M Tietgen, M Steinhauer, A Mateus, TG Schultze, ... bioRxiv, 2024.06. 04.597298, 2024 | | 2024 |