Competing and noncompeting activities of miR-122 and the 5′ exonuclease Xrn1 in regulation of hepatitis C virus replication Y Li, T Masaki, D Yamane, DR McGivern, SM Lemon Proceedings of the National Academy of Sciences 110 (5), 1881-1886, 2013 | 286 | 2013 |
Virus-specific mechanisms of carcinogenesis in hepatitis C virus associated liver cancer DR McGivern, SM Lemon Oncogene 30 (17), 1969-1983, 2011 | 239 | 2011 |
Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein T Munakata, Y Liang, S Kim, DR McGivern, J Huibregtse, A Nomoto, ... PLoS pathogens 3 (9), e139, 2007 | 173 | 2007 |
Unravelling the complexities of respiratory syncytial virus RNA synthesis VM Cowton, DR McGivern, R Fearns Journal of general virology 87 (7), 1805-1821, 2006 | 156 | 2006 |
Regulation of the hepatitis C virus RNA replicase by endogenous lipid peroxidation D Yamane, DR McGivern, E Wauthier, MK Yi, VJ Madden, C Welsch, ... Nature medicine 20 (8), 927-935, 2014 | 150 | 2014 |
Protease inhibitor–resistant hepatitis C virus mutants with reduced fitness from impaired production of infectious virus T Shimakami, C Welsch, D Yamane, DR McGivern, MK Yi, S Zeuzem, ... Gastroenterology 140 (2), 667-675, 2011 | 148 | 2011 |
miR-122 stimulates hepatitis C virus RNA synthesis by altering the balance of viral RNAs engaged in replication versus translation T Masaki, KC Arend, Y Li, D Yamane, DR McGivern, T Kato, T Wakita, ... Cell host & microbe 17 (2), 217-228, 2015 | 145 | 2015 |
Is hepatitis C virus carcinogenic? SM Lemon, DR McGivern Gastroenterology 142 (6), 1274-1278, 2012 | 133 | 2012 |
Kinetic analyses reveal potent and early blockade of hepatitis C virus assembly by NS5A inhibitors DR McGivern, T Masaki, S Williford, P Ingravallo, Z Feng, F Lahser, ... Gastroenterology 147 (2), 453-462. e7, 2014 | 128 | 2014 |
Requirement of cellular DDX3 for hepatitis C virus replication is unrelated to its interaction with the viral core protein AGN Angus, D Dalrymple, S Boulant, DR McGivern, RF Clayton, MJ Scott, ... Journal of general virology 91 (1), 122-132, 2010 | 112 | 2010 |
Tumor suppressors, chromosomal instability, and hepatitis C virus–associated liver cancer DR McGivern, SM Lemon Annual Review of Pathology: Mechanisms of Disease 4, 399-415, 2009 | 111 | 2009 |
Hepatitis C virus infection causes cell cycle arrest at the level of initiation of mitosis RP Kannan, LL Hensley, LE Evers, SM Lemon, DR McGivern Journal of virology 85 (16), 7989-8001, 2011 | 110 | 2011 |
MAVS-dependent host species range and pathogenicity of human hepatitis A virus A Hirai-Yuki, L Hensley, DR McGivern, O González-López, A Das, H Feng, ... Science 353 (6307), 1541-1545, 2016 | 90 | 2016 |
Liver injury and disease pathogenesis in chronic hepatitis C D Yamane, DR McGivern, T Masaki, SM Lemon Hepatitis C virus: from molecular virology to antiviral therapy, 263-288, 2013 | 90 | 2013 |
Class A scavenger receptor 1 (MSR1) restricts hepatitis C virus replication by mediating toll-like receptor 3 recognition of viral RNAs produced in neighboring cells H Dansako, D Yamane, C Welsch, DR McGivern, F Hu, N Kato, ... PLoS pathogens 9 (5), e1003345, 2013 | 82 | 2013 |
NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR H Feng, EM Lenarcic, D Yamane, E Wauthier, J Mo, H Guo, DR McGivern, ... Nature immunology 18 (12), 1299-1309, 2017 | 81 | 2017 |
Roles of the respiratory syncytial virus trailer region: effects of mutations on genome production and stress granule formation LL Hanley, DR McGivern, MN Teng, R Djang, PL Collins, R Fearns Virology 406 (2), 241-252, 2010 | 73 | 2010 |
Identification of internal sequences in the 3′ leader region of human respiratory syncytial virus that enhance transcription and confer replication processivity DR McGivern, PL Collins, R Fearns Journal of virology 79 (4), 2449-2460, 2005 | 71 | 2005 |
How do persistent infections with hepatitis C virus cause liver cancer? JK Mitchell, SM Lemon, DR McGivern Current opinion in virology 14, 101-108, 2015 | 64 | 2015 |
Chronic hepatitis C infection–induced liver fibrogenesis is associated with M2 macrophage activation MT Bility, K Nio, F Li, DR McGivern, SM Lemon, ER Feeney, RT Chung, ... Scientific reports 6 (1), 39520, 2016 | 63 | 2016 |