| Therapeutic activation of macrophages and microglia to suppress brain tumor-initiating cells S Sarkar, A Döring, FJ Zemp, C Silva, X Lun, X Wang, J Kelly, W Hader, ... Nature neuroscience 17 (1), 46-55, 2014 | 236 | 2014 |
| Proliferation of human glioblastoma stem cells occurs independently of exogenous mitogens JJP Kelly, O Stechishin, A Chojnacki, X Lun, B Sun, DL Senger, P Forsyth, ... Stem cells 27 (8), 1722-1733, 2009 | 226 | 2009 |
| The p75 neurotrophin receptor is a central regulator of glioma invasion ALM Johnston, X Lun, JJ Rahn, A Liacini, L Wang, MG Hamilton, ... PLoS biology 5 (8), e212, 2007 | 200 | 2007 |
| Myxoma virus is a novel oncolytic virus with significant antitumor activity against experimental human gliomas X Lun, W Yang, T Alain, ZQ Shi, H Muzik, JW Barrett, G McFadden, J Bell, ... Cancer research 65 (21), 9982-9990, 2005 | 194 | 2005 |
| Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide XQ Lun, JH Jang, N Tang, H Deng, R Head, JC Bell, DF Stojdl, CL Nutt, ... Clinical Cancer Research 15 (8), 2777-2788, 2009 | 193 | 2009 |
| Disulfiram when combined with copper enhances the therapeutic effects of temozolomide for the treatment of glioblastoma X Lun, JC Wells, N Grinshtein, JC King, X Hao, NH Dang, X Wang, ... Clinical Cancer Research 22 (15), 3860-3875, 2016 | 184 | 2016 |
| Vesicular stomatitis virus oncolysis is potentiated by impairing mTORC1-dependent type I IFN production T Alain, XQ Lun, Y Martineau, P Sean, B Pulendran, E Petroulakis, ... Proceedings of the National Academy of Sciences 107 (4), 1576-1581, 2010 | 160 | 2010 |
| Smac mimetics synergize with immune checkpoint inhibitors to promote tumour immunity against glioblastoma ST Beug, CE Beauregard, C Healy, T Sanda, M St-Jean, J Chabot, ... Nature Communications 8 (1), 14278, 2017 | 131 | 2017 |
| Glioma-derived IL-33 orchestrates an inflammatory brain tumor microenvironment that accelerates glioma progression A De Boeck, BY Ahn, C D’Mello, X Lun, SV Menon, MM Alshehri, ... Nature communications 11 (1), 4997, 2020 | 130 | 2020 |
| Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin XQ Lun, H Zhou, T Alain, B Sun, L Wang, JW Barrett, MM Stanford, ... Cancer research 67 (18), 8818-8827, 2007 | 123 | 2007 |
| Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin XQ Lun, T Alain, FJ Zemp, H Zhou, MM Rahman, MG Hamilton, ... Cancer research 70 (2), 598-608, 2010 | 121 | 2010 |
| Effects of Intravenously Administered Recombinant Vesicular Stomatitis Virus (VSV ΔM51 ) on Multifocal and Invasive Gliomas XQ Lun, DL Senger, T Alain, A Oprea, K Parato, D Stojdl, B Lichty, ... Journal of the National Cancer Institute 98 (21), 1546-1557, 2006 | 115 | 2006 |
| Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma XQ Lun, J Chan, H Zhou, B Sun, JJP Kelly, OO Stechishin, JC Bell, ... Molecular Therapy 18 (11), 1927-1936, 2010 | 113 | 2010 |
| Proteolytic disassembly is a critical determinant for reovirus oncolysis T Alain, TSY Kim, XQ Lun, A Liacini, LA Schiff, DL Senger, PA Forsyth Molecular Therapy 15 (8), 1512-1521, 2007 | 104 | 2007 |
| Efficacy and safety evaluation of human reovirus type 3 in immunocompetent animals: racine and nonhuman primates WQ Yang, X Lun, CA Palmer, ME Wilcox, H Muzik, ZQ Shi, R Dyck, ... Clinical cancer research 10 (24), 8561-8576, 2004 | 99 | 2004 |
| Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor LM Wang, JJ Rahn, XQ Lun, B Sun, JJP Kelly, S Weiss, SM Robbins, ... PLoS biology 6 (11), e289, 2008 | 93 | 2008 |
| Oncolytic viruses as experimental treatments for malignant gliomas: using a scourge to treat a devil FJ Zemp, JC Corredor, X Lun, DA Muruve, PA Forsyth Cytokine & growth factor reviews 21 (2-3), 103-117, 2010 | 82 | 2010 |
| Oncolytic efficacy of recombinant vesicular stomatitis virus and myxoma virus in experimental models of rhabdoid tumors Y Wu, X Lun, H Zhou, L Wang, B Sun, JC Bell, JW Barrett, G McFadden, ... Clinical Cancer Research 14 (4), 1218-1227, 2008 | 65 | 2008 |
| Myxoma Virus Infection Promotes NK Lysis of Malignant Gliomas In Vitro and In Vivo H Ogbomo, FJ Zemp, X Lun, J Zhang, D Stack, MM Rahman, G Mcfadden, ... PloS one 8 (6), e66825, 2013 | 64 | 2013 |
| Reovirus as an experimental therapeutic for brain and leptomeningeal metastases from breast cancer WQ Yang, DL Senger, XQ Lun, H Muzik, ZQ Shi, RH Dyck, K Norman, ... Gene therapy 11 (21), 1579-1589, 2004 | 60 | 2004 |
