Molecular docking and dynamics simulation revealed the potential inhibitory activity of ACEIs against SARS-CoV-2 targeting hACE2 receptor I Eissa, A Al-Karmalawy, MA Dahab, AM Metwaly, SS Elhady, EB Elkaeed, ... Frontiers in Chemistry 9, 227, 2021 | 172* | 2021 |
Design, synthesis, molecular modeling, in vivo studies and anticancer evaluation of quinazolin-4 (3H)-one derivatives as potential VEGFR-2 inhibitors and apoptosis inducers HA Mahdy, MK Ibrahim, AM Metwaly, A Belal, ABM Mehany, ... Bioorganic Chemistry 94, 103422, 2020 | 133 | 2020 |
Black ginseng and its saponins: Preparation, phytochemistry and pharmacological effects AM Metwaly, Z Lianlian, H Luqi, D Deqiang Molecules 24 (10), 1856, 2019 | 114 | 2019 |
Traditional ancient Egyptian medicine: A review AM Metwaly, MM Ghoneim, IH Eissa, IA Elsehemy, AE Mostafa, ... Saudi journal of biological sciences 28 (10), 5823-5832, 2021 | 110 | 2021 |
Design, synthesis, molecular modeling and anti-proliferative evaluation of novel quinoxaline derivatives as potential DNA intercalators and topoisomerase II inhibitors MK Ibrahim, MS Taghour, AM Metwaly, A Belal, ABM Mehany, ... European journal of medicinal chemistry 155, 117-134, 2018 | 110 | 2018 |
Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of quinazolin-4(3H)-one derivatives as potential PPARγ and SUR agonists MK Ibrahim, IH Eissa, MS Alesawy, AM Metwaly, MM Radwan, ... Bioorganic & medicinal chemistry 25 (17), 4723-4744, 2017 | 86 | 2017 |
Nigrosphaerin A a new isochromene derivative from the endophytic fungus Nigrospora sphaerica AM Metwaly, HA Kadry, A Atef, AEI Mohammad, G Ma, SJ Cutler, SA Ross Phytochemistry letters 7, 1-5, 2014 | 86 | 2014 |
Comprehensive virtual screening of the antiviral potentialities of marine polycyclic guanidine alkaloids against SARS-CoV-2 (COVID-19) A El-Demerdash, AM Metwaly, A Hassan, TM Abd El-Aziz, EB Elkaeed, ... Biomolecules 11 (3), 460, 2021 | 81 | 2021 |
Design, synthesis, docking, DFT, MD simulation studies of a new nicotinamide-based derivative: in vitro anticancer and VEGFR-2 inhibitory effects EB Elkaeed, RG Yousef, H Elkady, IMM Gobaara, BA Alsfouk, DZ Husein, ... Molecules 27 (14), 4606, 2022 | 79 | 2022 |
Design, synthesis, molecular modeling and anti-hyperglycemic evaluation of novel quinoxaline derivatives as potential PPARγ and SUR agonists MK Ibrahim, IH Eissa, AE Abdallah, AM Metwaly, MM Radwan, ... Bioorganic & medicinal chemistry 25 (4), 1496-1513, 2017 | 79 | 2017 |
Design, molecular docking, in vitro, and in vivo studies of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors with potential activity against hepatocellular carcinoma IH Eissa, MK Ibrahim, AM Metwaly, A Belal, ABM Mehany, AA Abdelhady, ... Bioorganic Chemistry 107, 104532, 2021 | 75 | 2021 |
Design, synthesis, and anti-proliferative evaluation of new quinazolin-4 (3H)-ones as potential VEGFR-2 inhibitors K El-Adl, AGA El-Helby, RR Ayyad, HA Mahdy, MM Khalifa, HA Elnagar, ... Bioorganic & Medicinal Chemistry 29, 115872, 2021 | 75 | 2021 |
Design and synthesis of thiazolidine-2, 4-diones hybrids with 1, 2-dihydroquinolones and 2-oxindoles as potential VEGFR-2 inhibitors: In-vitro anticancer evaluation and in … MS Taghour, H Elkady, WM Eldehna, NM El-Deeb, AM Kenawy, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 1903-1917, 2022 | 73 | 2022 |
Discovery of new quinazolin-4 (3H)-ones as VEGFR-2 inhibitors: Design, synthesis, and anti-proliferative evaluation IH Eissa, AGA El-Helby, HA Mahdy, MM Khalifa, HA Elnagar, ... Bioorganic Chemistry 105, 104380, 2020 | 71 | 2020 |
Discovery of new anticancer thiourea-azetidine hybrids: Design, synthesis, in vitro antiproliferative, SAR, in silico molecular docking against VEGFR-2, ADMET, toxicity, and … DR Parmar, JY Soni, R Guduru, RH Rayani, RV Kusurkar, AG Vala, ... Bioorganic Chemistry 115, 105206, 2021 | 69 | 2021 |
Discovery of new quinoxaline-2 (1H)-one-based anticancer agents targeting VEGFR-2 as inhibitors: Design, synthesis, and anti-proliferative evaluation K El-Adl, HM Sakr, RG Yousef, ABM Mehany, AM Metwaly, ... Bioorganic Chemistry 114, 105105, 2021 | 67 | 2021 |
New combination approaches to combat methicillin-resistant Staphylococcus aureus (MRSA) MH Sharaf, GM El-Sherbiny, SA Moghannem, M Abdelmonem, ... Scientific reports 11 (1), 4240, 2021 | 65 | 2021 |
Discovery and antiproliferative evaluation of new quinoxalines as potential DNA intercalators and topoisomerase II inhibitors IH Eissa, AM Metwaly, A Belal, ABM Mehany, RR Ayyad, K El‐Adl, ... Archiv der Pharmazie 352 (11), 1900123, 2019 | 65 | 2019 |
New quinoxaline-2 (1H)-ones as potential VEGFR-2 inhibitors: Design, synthesis, molecular docking, ADMET profile and anti-proliferative evaluations R Yousef, H Sakr, I Eissa, A Mehany, A Metwaly, MA Elhendawy, ... New Journal of Chemistry, 2021 | 63 | 2021 |
Molecular docking and dynamics simulations reveal the potential of anti-HCV drugs to inhibit COVID-19 main protease IE Ahmed Ali Al-Karmalawy, Radwan Alnajjar, Mohammed Dahab, Ahmed Metwaly Pharmaceutical Sciences, 2021 | 60* | 2021 |