Surface acetylation of polyamidoamine (PAMAM) dendrimers decreases cytotoxicity while maintaining membrane permeability RB Kolhatkar, KM Kitchens, PW Swaan, H Ghandehari Bioconjugate chemistry 18 (6), 2054-2060, 2007 | 345 | 2007 |
Endocytosis and interaction of poly (amidoamine) dendrimers with Caco-2 cells KM Kitchens, AB Foraker, RB Kolhatkar, PW Swaan, H Ghandehari Pharmaceutical research 24, 2138-2145, 2007 | 218 | 2007 |
Transport of poly (amidoamine) dendrimers across Caco-2 cell monolayers: influence of size, charge and fluorescent labeling KM Kitchens, RB Kolhatkar, PW Swaan, ND Eddington, H Ghandehari Pharmaceutical research 23, 2818-2826, 2006 | 211 | 2006 |
Endocytosis inhibitors prevent poly (amidoamine) dendrimer internalization and permeability across Caco-2 cells KM Kitchens, RB Kolhatkar, PW Swaan, H Ghandehari Molecular pharmaceutics 5 (2), 364-369, 2008 | 182 | 2008 |
Potential oral delivery of 7-ethyl-10-hydroxy-camptothecin (SN-38) using poly (amidoamine) dendrimers RB Kolhatkar, P Swaan, H Ghandehari Pharmaceutical research 25, 1723-1729, 2008 | 138 | 2008 |
Transepithelial transport of PEGylated anionic poly (amidoamine) dendrimers: implications for oral drug delivery DM Sweet, RB Kolhatkar, A Ray, P Swaan, H Ghandehari Journal of controlled release 138 (1), 78-85, 2009 | 115 | 2009 |
Dopamine transporter as target for drug development of cocaine dependence medications AK Dutta, S Zhang, R Kolhatkar, MEA Reith European journal of pharmacology 479 (1-3), 93-106, 2003 | 79 | 2003 |
Active tumor targeting of nanomaterials using folic acid, transferrin and integrin receptors R Kolhatkar, A Lote, H Khambhati Current drug discovery technologies 8 (3), 197-206, 2011 | 69 | 2011 |
Synthesis and biological characterization of novel hybrid 7-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5, 6, 7, 8-tetrahydro-naphthalen-2-ol and their heterocyclic … AK Dutta, SK Venkataraman, XS Fei, R Kolhatkar, S Zhang, MEA Reith Bioorganic & medicinal chemistry 12 (16), 4361-4373, 2004 | 66 | 2004 |
Tumor-targeted HPMA copolymer-(RGDfK)-(CHX-A ″-DTPA) conjugates show increased kidney accumulation MP Borgman, T Coleman, RB Kolhatkar, S Geyser-Stoops, BR Line, ... Journal of Controlled Release 132 (3), 193-199, 2008 | 64 | 2008 |
Targetable HPMA copolymer–aminohexylgeldanamycin conjugates for prostate cancer therapy MP Borgman, A Ray, RB Kolhatkar, EA Sausville, AM Burger, ... Pharmaceutical research 26, 1407-1418, 2009 | 48 | 2009 |
Influence of oligospermines architecture on their suitability for siRNA delivery M Elsayed, V Corrand, V Kolhatkar, Y Xie, NH Kim, R Kolhatkar, ... Biomacromolecules 15 (4), 1299-1310, 2014 | 40 | 2014 |
Interaction of cis-(6-Benzhydrylpiperidin-3-yl)benzylamine Analogues with Monoamine Transporters: Structure−Activity Relationship Study of Structurally … RB Kolhatkar, SK Ghorai, C George, MEA Reith, AK Dutta Journal of medicinal chemistry 46 (11), 2205-2215, 2003 | 39 | 2003 |
Complexes of bacterial nicotinate mononucleotide adenylyltransferase with inhibitors: implication for structure-based drug design and improvement N Huang, R Kolhatkar, Y Eyobo, L Sorci, I Rodionova, AL Osterman, ... Journal of medicinal chemistry 53 (14), 5229-5239, 2010 | 37 | 2010 |
Cathepsin B degradable star-shaped peptidic macromolecules for delivery of 2-methoxyestradiol R Shankar, A Samykutty, C Riggin, S Kannan, U Wenzel, R Kolhatkar Molecular pharmaceutics 10 (10), 3776-3788, 2013 | 36 | 2013 |
Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl) benzylamine with elucidation of bioactive conformation: discovery of 1, 4-diazabicyclo [3.3. 1 … R Kolhatkar, CD Cook, SK Ghorai, J Deschamps, PM Beardsley, ... Journal of medicinal chemistry 47 (21), 5101-5113, 2004 | 20 | 2004 |
Targeting NAD biosynthesis in bacterial pathogens A MacKerell, H Zhang, A Osterman, R Kolhatkar US Patent 8,785,499, 2014 | 16 | 2014 |
Functionalized dendrimers as nanoscale drug carriers R Kolhatkar, D Sweet, H Ghandehari Multifunctional pharmaceutical nanocarriers, 201-232, 2008 | 12 | 2008 |
Star-shaped tetraspermine enhances cellular uptake and cytotoxicity of T-oligo in prostate cancer cells V Kolhatkar, H Khambati, A Lote, P Shanine, T Insley, S Sen, ... Pharmaceutical research 32, 196-210, 2015 | 10 | 2015 |
Further structural optimization of cis-(6-benzhydryl-piperidin-3-yl)-benzylamine and 1, 4-diazabicyclo [3.3. 1] nonane derivatives by introducing an exocyclic hydroxyl group … M Mishra, R Kolhatkar, J Zhen, I Parrington, MEA Reith, AK Dutta Bioorganic & medicinal chemistry 16 (6), 2769-2778, 2008 | 9 | 2008 |