Heterocycles as key substrates in multicomponent reactions: the fast lane towards molecular complexity N Isambert, R Lavilla Chemistry–A European Journal 14 (28), 8444-8454, 2008 | 390 | 2008 |
Chemical and biological aspects of Narcissus alkaloids J Bastida, R Lavilla, F Viladomat The alkaloids: chemistry and biology 63, 87-179, 2006 | 369 | 2006 |
Recent developments in the chemistry of dihydropyridines R Lavilla Journal of the Chemical Society, Perkin Transactions 1, 1141-1156, 2002 | 361 | 2002 |
New peptide architectures through C–H activation stapling between tryptophan–phenylalanine/tyrosine residues L Mendive-Tapia, S Preciado, J García, R Ramón, N Kielland, F Albericio, ... Nature communications 6 (1), 7160, 2015 | 261 | 2015 |
Pyrano[3,2-c]quinoline−6-Chlorotacrine Hybrids as a Novel Family of Acetylcholinesterase- and β-Amyloid-Directed Anti-Alzheimer Compounds P Camps, X Formosa, C Galdeano, D Munoz-Torrero, L Ramirez, ... Journal of medicinal chemistry 52 (17), 5365-5379, 2009 | 231 | 2009 |
Postsynthetic modification of peptides: chemoselective C‐arylation of tryptophan residues J Ruiz‐Rodríguez, F Albericio, R Lavilla Chemistry–A European Journal 16 (4), 1124-1127, 2010 | 191 | 2010 |
Mechanistic variations of the Povarov multicomponent reaction and related processes D Bello, R Ramon, R Lavilla Current Organic Chemistry 14 (4), 332-356, 2010 | 150 | 2010 |
Polyene synthesis. Ready construction of retinol-carotene fragments,(.+-.)-6 (E)-LTB3 leukotrienes, and corticrocin E Wenkert, M Guo, R Lavilla, B Porter, K Ramachandran, JH Sheu The Journal of Organic Chemistry 55 (25), 6203-6214, 1990 | 143 | 1990 |
Multicomponent Reactions for de Novo Synthesis of BODIPY Probes: In Vivo Imaging of Phagocytic Macrophages A Vazquez-Romero, N Kielland, MJ Arevalo, S Preciado, RJ Mellanby, ... Journal of the American Chemical Society 135 (43), 16018-16021, 2013 | 140 | 2013 |
Spacer-free BODIPY fluorogens in antimicrobial peptides for direct imaging of fungal infection in human tissue L Mendive-Tapia, C Zhao, AR Akram, S Preciado, F Albericio, M Lee, ... Nature Communications 7 (1), 10940, 2016 | 133 | 2016 |
Synthesis of C-2 arylated tryptophan amino acids and related compounds through palladium-catalyzed C–H activation S Preciado, L Mendive-Tapia, F Albericio, R Lavilla The Journal of Organic Chemistry 78 (16), 8129-8135, 2013 | 128 | 2013 |
Modern synthetic avenues for the preparation of functional fluorophores F de Moliner, N Kielland, R Lavilla, M Vendrell Angewandte Chemie International Edition 56 (14), 3758-3769, 2017 | 126 | 2017 |
Tacrine-based dual binding site acetylcholinesterase inhibitors as potential disease-modifying anti-Alzheimer drug candidates P Camps, X Formosa, C Galdeano, T Gómez, D Muñoz-Torrero, ... Chemico-biological interactions 187 (1-3), 411-415, 2010 | 111 | 2010 |
Recent advances of the Povarov reaction in medicinal chemistry O Ghashghaei, C Masdeu, C Alonso, F Palacios, R Lavilla Drug Discovery Today: Technologies 29, 71-79, 2018 | 99 | 2018 |
Straightforward access to a structurally diverse set of oxacyclic scaffolds through a four‐component reaction O Jiménez, G de la Rosa, R Lavilla Angewandte Chemie International Edition 44 (40), 6521-6525, 2005 | 99 | 2005 |
Dihydropyridine-based multicomponent reactions. Efficient entry into new tetrahydroquinoline systems through Lewis acid-catalyzed formal [4+ 2] cycloadditions R Lavilla, MC Bernabeu, I Carranco, JL Díaz Organic Letters 5 (5), 717-720, 2003 | 95 | 2003 |
N-Acylazinium Salts: A New Source of Iminium Ions for Ugi-Type Processes JL Díaz, M Miguel, R Lavilla The Journal of organic chemistry 69 (10), 3550-3553, 2004 | 89 | 2004 |
Endothelin-1 promotes vascular smooth muscle cell migration across the artery wall: a mechanism contributing to vascular remodelling and intimal hyperplasia in giant-cell arteritis E Planas-Rigol, N Terrades-Garcia, M Corbera-Bellalta, E Lozano, ... Annals of the rheumatic diseases 76 (9), 1624-1634, 2017 | 85 | 2017 |
Unsaturated lactams: new inputs for Povarov-type multicomponent reactions E Vicente-Garcia, F Catti, R Ramón, R Lavilla Organic Letters 12 (4), 860-863, 2010 | 78 | 2010 |
Enol esters: Versatile substrates for Mannich-Type multicomponent reactions N Isambert, M Cruz, MJ Arévalo, E Gomez, R Lavilla Organic Letters 9 (21), 4199-4202, 2007 | 76 | 2007 |