| The fragile X syndrome protein FMRP associates with BC1 RNA and regulates the translation of specific mRNAs at synapses F Zalfa, M Giorgi, B Primerano, A Moro, A Di Penta, S Reis, B Oostra, ... Cell 112 (3), 317-327, 2003 | 845 | 2003 |
| Epigenetic characterization of the FMR1 gene and aberrant neurodevelopment in human induced pluripotent stem cell models of fragile X syndrome SD Sheridan, KM Theriault, SA Reis, F Zhou, JM Madison, L Daheron, ... PloS one 6 (10), e26203, 2011 | 344 | 2011 |
| The FMR1 CGG repeat mouse displays ubiquitin-positive intranuclear neuronal inclusions; implications for the cerebellar tremor/ataxia syndrome R Willemsen, M Hoogeveen-Westerveld, S Reis, J Holstege, ... Human molecular genetics 12 (9), 949-959, 2003 | 282 | 2003 |
| An aldol-based build/couple/pair strategy for the synthesis of medium-and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors LA Marcaurelle, E Comer, S Dandapani, JR Duvall, B Gerard, S Kesavan, ... Journal of the American Chemical Society 132 (47), 16962-16976, 2010 | 232 | 2010 |
| Fxr1 knockout mice show a striated muscle phenotype: implications for Fxr1p function in vivo EJ Mientjes, R Willemsen, LL Kirkpatrick, IM Nieuwenhuizen, ... Human molecular genetics 13 (13), 1291-1302, 2004 | 178 | 2004 |
| A selective HDAC 1/2 inhibitor modulates chromatin and gene expression in brain and alters mouse behavior in two mood-related tests FA Schroeder, MC Lewis, DM Fass, FF Wagner, YL Zhang, KM Hennig, ... PloS one 8 (8), e71323, 2013 | 156 | 2013 |
| Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers FF Wagner, YL Zhang, DM Fass, N Joseph, JP Gale, M Weïwer, ... Chemical science 6 (1), 804-815, 2015 | 117 | 2015 |
| Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity DM Fass, SA Reis, B Ghosh, KM Hennig, NF Joseph, WN Zhao, ... Neuropharmacology 64, 81-96, 2013 | 112 | 2013 |
| In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs C Wang, FA Schroeder, HY Wey, R Borra, FF Wagner, S Reis, SW Kim, ... Journal of medicinal chemistry 57 (19), 7999-8009, 2014 | 100 | 2014 |
| Monoalkoxy BODIPYs A Fluorophore Class for Bioimaging AM Courtis, SA Santos, Y Guan, JA Hendricks, B Ghosh, DM Szantai-Kis, ... Bioconjugate chemistry 25 (6), 1043-1051, 2014 | 97 | 2014 |
| A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy I Hernandez, G Luna, JN Rauch, SA Reis, M Giroux, CM Karch, D Boctor, ... Science translational medicine 11 (485), eaat3005, 2019 | 87 | 2019 |
| Light-controlled modulation of gene expression by chemical optoepigenetic probes SA Reis, B Ghosh, JA Hendricks, DM Szantai-Kis, L Törk, KN Ross, ... Nature chemical biology 12 (5), 317-323, 2016 | 81 | 2016 |
| Kinetic and structural insights into the binding of histone deacetylase 1 and 2 (HDAC1, 2) inhibitors FF Wagner, M Weïwer, S Steinbacher, A Schomburg, P Reinemer, ... Bioorganic & medicinal chemistry 24 (18), 4008-4015, 2016 | 74 | 2016 |
| Effect of inhibiting histone deacetylase with short-chain carboxylic acids and their hydroxamic acid analogs on vertebrate development and neuronal chromatin DM Fass, R Shah, B Ghosh, K Hennig, S Norton, WN Zhao, SA Reis, ... ACS medicinal chemistry letters 2 (1), 39, 2010 | 54 | 2010 |
| Short-chain HDAC inhibitors differentially affect vertebrate development and neuronal chromatin DM Fass, R Shah, B Ghosh, K Hennig, S Norton, WN Zhao, SA Reis, ... ACS Medicinal Chemistry Letters 2 (1), 39-42, 2011 | 51 | 2011 |
| Transport kinetics of FMRP containing the I304N mutation of severe fragile X syndrome in neurites of living rat PC12 cells M Schrier, LA Severijnen, S Reis, M Rife, S van't Padje, G van Cappellen, ... Experimental neurology 189 (2), 343-353, 2004 | 49 | 2004 |
| Selectivity and kinetic requirements of HDAC inhibitors as progranulin enhancers for treating frontotemporal dementia A She, I Kurtser, SA Reis, K Hennig, J Lai, A Lang, WN Zhao, ... Cell chemical biology 24 (7), 892-906. e5, 2017 | 46 | 2017 |
| Striatal neurons expressing full-length mutant huntingtin exhibit decreased N-cadherin and altered neuritogenesis SA Reis, MN Thompson, JM Lee, E Fossale, HH Kim, JK Liao, ... Human molecular genetics 20 (12), 2344-2355, 2011 | 42 | 2011 |
| TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling P Martin, V Wagh, SA Reis, S Erdin, RL Beauchamp, G Shaikh, ... Molecular autism 11, 1-15, 2020 | 41 | 2020 |
| PET imaging demonstrates histone deacetylase target engagement and clarifies brain penetrance of known and novel small molecule inhibitors in rat FA Schroeder, C Wang, GC Van de Bittner, R Neelamegam, ... ACS chemical neuroscience 5 (10), 1055-1062, 2014 | 40 | 2014 |
