| Nitric oxide modulates metabolic remodeling in inflammatory macrophages through TCA cycle regulation and itaconate accumulation JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphichai, ... Cell reports 28 (1), 218-230. e7, 2019 | 188 | 2019 |
| Reduction of neuropathic and inflammatory pain through inhibition of the tetrahydrobiopterin pathway A Latremoliere, A Latini, N Andrews, SJ Cronin, M Fujita, K Gorska, ... Neuron 86 (6), 1393-1406, 2015 | 158 | 2015 |
| Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation E McNeill, MJ Crabtree, N Sahgal, J Patel, S Chuaiphichai, AJ Iqbal, ... Free Radical Biology and Medicine 79, 206-216, 2015 | 157 | 2015 |
| Effects of canagliflozin on human myocardial redox signalling: clinical implications H Kondo, I Akoumianakis, I Badi, N Akawi, CP Kotanidis, M Polkinghorne, ... European Heart Journal 42 (48), 4947-4960, 2021 | 81 | 2021 |
| Fat-secreted ceramides regulate vascular redox state and influence outcomes in patients with cardiovascular disease N Akawi, A Checa, AS Antonopoulos, I Akoumianakis, E Daskalaki, ... Journal of the American College of Cardiology 77 (20), 2494-2513, 2021 | 71 | 2021 |
| Adipose tissue–derived WNT5A regulates vascular redox signaling in obesity via USP17/RAC1-mediated activation of NADPH oxidases I Akoumianakis, F Sanna, M Margaritis, I Badi, N Akawi, L Herdman, ... Science translational medicine 11 (510), eaav5055, 2019 | 70 | 2019 |
| Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation S Chuaiphichai, E McNeill, G Douglas, MJ Crabtree, JK Bendall, AB Hale, ... Hypertension 64 (3), 530-540, 2014 | 67 | 2014 |
| Isolation and culture of murine bone marrow-derived macrophages for nitric oxide and redox biology JD Bailey, A Shaw, E McNeill, T Nicol, M Diotallevi, S Chuaiphichai, ... Nitric Oxide 100, 17-29, 2020 | 50 | 2020 |
| Roles for endothelial cell and macrophage Gch1 and tetrahydrobiopterin in atherosclerosis progression G Douglas, AB Hale, J Patel, S Chuaiphichai, A Al Haj Zen, ... Cardiovascular Research 114 (10), 1385-1399, 2018 | 44 | 2018 |
| A key role for tetrahydrobiopterin‐dependent endothelial NOS regulation in resistance arteries: studies in endothelial cell tetrahydrobiopterin‐deficient mice S Chuaiphichai, MJ Crabtree, E Mcneill, AB Hale, L Trelfa, KM Channon, ... British Journal of Pharmacology 174 (8), 657-671, 2017 | 41 | 2017 |
| A key role for the novel coronary artery disease gene JCAD in atherosclerosis via shear stress mechanotransduction G Douglas, V Mehta, A Al Haj Zen, I Akoumianakis, A Goel, VS Rashbrook, ... Cardiovascular research 116 (11), 1863-1874, 2020 | 35 | 2020 |
| Endothelial cell tetrahydrobiopterin modulates sensitivity to Ang (Angiotensin) II–induced vascular remodeling, blood pressure, and abdominal aortic aneurysm S Chuaiphichai, VS Rashbrook, AB Hale, L Trelfa, J Patel, E McNeill, ... Hypertension 72 (1), 128-138, 2018 | 28 | 2018 |
| A pivotal role for tryptophan 447 in enzymatic coupling of human endothelial nitric oxide synthase (eNOS): effects on tetrahydrobiopterin-dependent catalysis and eNOS dimerization MA Benson, H Batchelor, S Chuaiphichai, J Bailey, H Zhu, DJ Stuehr, ... Journal of Biological Chemistry 288 (41), 29836-29845, 2013 | 28 | 2013 |
| Vascular wall regulator of G-protein signalling-1 (RGS-1) is required for angiotensin II–mediated blood pressure control J Patel, S Chuaiphichai, G Douglas, CM Gorvin, KM Channon Vascular pharmacology 108, 15-22, 2018 | 25 | 2018 |
| Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension S Chuaiphichai, A Starr, M Nandi, KM Channon, E McNeill Vascular Pharmacology 77, 69-79, 2016 | 25 | 2016 |
| Insulin-induced vascular redox dysregulation in human atherosclerosis is ameliorated by dipeptidyl peptidase 4 inhibition I Akoumianakis, I Badi, G Douglas, S Chuaiphichai, L Herdman, N Akawi, ... Science translational medicine 12 (541), eaav8824, 2020 | 22 | 2020 |
| BH4 increases nNOS activity and preserves left ventricular function in diabetes R Carnicer, D Duglan, K Ziberna, A Recalde, S Reilly, JN Simon, S Mafrici, ... Circulation research 128 (5), 585-601, 2021 | 18 | 2021 |
| Endothelial GTPCH (GTP cyclohydrolase 1) and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling, and fetal growth S Chuaiphichai, GZ Yu, CMJ Tan, C Whiteman, G Douglas, Y Dickinson, ... Hypertension 78 (6), 1871-1884, 2021 | 12 | 2021 |
| Nitric oxide modulates metabolic remodeling in inflammatory macrophages through TCA cycle regulation and itaconate accumulation. Cell Rep 28: 218-230. e7 JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphichai, ... | 11 | 2019 |
| Crucial role for neuronal nitric oxide synthase in early microcirculatory derangement and recipient survival following murine pancreas transplantation B Cardini, K Watschinger, M Hermann, P Obrist, R Oberhuber, ... PLoS One 9 (11), e112570, 2014 | 10 | 2014 |
