Nuclear factor E2-related factor-2 negatively regulates NLRP3 inflammasome activity by inhibiting reactive oxygen species-induced NLRP3 priming X Liu, X Zhang, Y Ding, W Zhou, L Tao, P Lu, Y Wang, R Hu Antioxidants & redox signaling 26 (1), 28-43, 2017 | 207 | 2017 |
Macrophage-derived CCL5 facilitates immune escape of colorectal cancer cells via the p65/STAT3-CSN5-PD-L1 pathway C Liu, Z Yao, J Wang, W Zhang, Y Yang, Y Zhang, X Qu, Y Zhu, J Zou, ... Cell Death & Differentiation 27 (6), 1765-1781, 2020 | 145 | 2020 |
Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation X Liu, W Zhou, X Zhang, P Lu, Q Du, L Tao, Y Ding, Y Wang, R Hu Biochemical pharmacology 112, 37-49, 2016 | 135 | 2016 |
Rethinking immune checkpoint blockade:‘Beyond the T cell’ X Liu, GD Hogg, DG DeNardo Journal for immunotherapy of cancer 9 (1), 2021 | 105 | 2021 |
Development of resistance to FAK inhibition in pancreatic cancer is linked to stromal depletion H Jiang, X Liu, BL Knolhoff, S Hegde, KB Lee, H Jiang, RC Fields, ... Gut 69 (1), 122-132, 2020 | 104 | 2020 |
Dietary cholesterol promotes AOM-induced colorectal cancer through activating the NLRP3 inflammasome Q Du, Q Wang, H Fan, J Wang, X Liu, H Wang, Y Wang, R Hu Biochemical pharmacology 105, 42-54, 2016 | 97 | 2016 |
Ginsenoside Rd ameliorates colitis by inducing p62-driven mitophagy-mediated NLRP3 inflammasome inactivation in mice C Liu, J Wang, Y Yang, X Liu, Y Zhu, J Zou, S Peng, TH Le, Y Chen, ... Biochemical Pharmacology 155, 366-379, 2018 | 82 | 2018 |
3-(2-Oxo-2-phenylethylidene)-2, 3, 6, 7-tetrahydro-1H-pyrazino [2, 1-a] isoquinolin-4 (11bH)-one (compound 1), a novel potent Nrf2/ARE inducer, protects against DSS-induced … Y Wang, H Wang, C Qian, J Tang, W Zhou, X Liu, Q You, R Hu Biochemical Pharmacology 101, 71-86, 2016 | 58 | 2016 |
FoxO3 reverses 5-fluorouracil resistance in human colorectal cancer cells by inhibiting the Nrf2/TR1 signaling pathway C Liu, Y Zhao, J Wang, Y Yang, Y Zhang, X Qu, S Peng, Z Yao, S Zhao, ... Cancer letters 470, 29-42, 2020 | 52 | 2020 |
Gen-27, a newly synthesized flavonoid, inhibits glycolysis and induces cell apoptosis via suppression of hexokinase II in human breast cancer cells L Tao, L Wei, Y Liu, Y Ding, X Liu, X Zhang, X Wang, Y Yao, J Lu, Q Wang, ... Biochemical pharmacology 125, 12-25, 2017 | 52 | 2017 |
Oroxylin A inhibits colitis by inactivating NLRP3 inflammasome W Zhou, X Liu, X Zhang, J Tang, Z Li, Q Wang, R Hu Oncotarget 8 (35), 58903, 2017 | 47 | 2017 |
1‐L‐MT, an IDO inhibitor, prevented colitis‐associated cancer by inducing CDC20 inhibition‐mediated mitotic death of colon cancer cells X Liu, W Zhou, X Zhang, Y Ding, Q Du, R Hu International Journal of Cancer 143 (6), 1516-1529, 2018 | 44 | 2018 |
Blockade of IDO-kynurenine-AhR axis ameliorated colitis-associated colon cancer via inhibiting immune tolerance X Zhang, X Liu, W Zhou, Q Du, M Yang, Y Ding, R Hu Cellular and molecular gastroenterology and hepatology 12 (4), 1179-1199, 2021 | 43 | 2021 |
Stromal reprogramming by FAK inhibition overcomes radiation resistance to allow for immune priming and response to checkpoint blockade VE Lander, JI Belle, NL Kingston, JM Herndon, GD Hogg, X Liu, LI Kang, ... Cancer discovery 12 (12), 2774-2799, 2022 | 31 | 2022 |
Fasudil increases temozolomide sensitivity and suppresses temozolomide-resistant glioma growth via inhibiting ROCK2/ABCG2 X Zhang, X Liu, W Zhou, M Yang, Y Ding, Q Wang, R Hu Cell death & disease 9 (2), 190, 2018 | 30 | 2018 |
Malignant gliomas induce and exploit astrocytic mesenchymal-like transition by activating canonical Wnt/β-catenin signaling P Lu, Y Wang, X Liu, H Wang, X Zhang, K Wang, Q Wang, R Hu Medical oncology 33, 1-11, 2016 | 25 | 2016 |
IRAK4 signaling drives resistance to checkpoint immunotherapy in pancreatic ductal adenocarcinoma VK Somani, D Zhang, PB Dodhiawala, VE Lander, X Liu, LI Kang, ... Gastroenterology 162 (7), 2047-2062, 2022 | 22 | 2022 |
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity X Liu, GD Hogg, C Zuo, NC Borcherding, JM Baer, VE Lander, LI Kang, ... Cancer Cell 41 (6), 1073-1090. e12, 2023 | 19 | 2023 |
X-11-5-27, a daidzein derivative, inhibits NLRP3 inflammasome activity via promoting autophagy W Zhou, X Liu, K Cheng, X Zhang, J Lu, R Hu Experimental cell research 360 (2), 320-327, 2017 | 18 | 2017 |
Epigenetic regulation during cancer transitions across 11 tumour types NV Terekhanova, A Karpova, WW Liang, A Strzalkowski, S Chen, Y Li, ... Nature 623 (7986), 432-441, 2023 | 13 | 2023 |