Anionic nanoparticles enable the oral delivery of proteins by enhancing intestinal permeability NG Lamson, A Berger, KC Fein, KA Whitehead Nature biomedical engineering 4 (1), 84-96, 2020 | 224 | 2020 |
ATRP-grown protein-polymer conjugates containing phenylpiperazine selectively enhance transepithelial protein transport CS Cummings, K Fein, H Murata, RL Ball, AJ Russell, KA Whitehead Journal of Controlled Release 255, 270-278, 2017 | 28 | 2017 |
Oral delivery of peptide therapeutics in infants: Challenges and opportunities JP Gleeson, KC Fein, KA Whitehead Advanced drug delivery reviews 173, 112-124, 2021 | 24 | 2021 |
Structure-function analysis of phenylpiperazine derivatives as intestinal permeation enhancers KC Fein, NG Lamson, KA Whitehead Pharmaceutical Research 34, 1320-1329, 2017 | 24 | 2017 |
The enhanced intestinal permeability of infant mice enables oral protein and macromolecular absorption without delivery technology JP Gleeson, KC Fein, N Chaudhary, R Doerfler, AN Newby, ... International journal of pharmaceutics 593, 120120, 2021 | 22 | 2021 |
Profiling of mature-stage human breast milk cells identifies six unique lactocyte subpopulations JP Gleeson, N Chaudhary, KC Fein, R Doerfler, P Hredzak-Showalter, ... Science Advances 8 (26), eabm6865, 2022 | 20 | 2022 |
Intestinal permeation enhancers enable oral delivery of macromolecules up to 70 kDa in size KC Fein, JP Gleeson, AN Newby, KA Whitehead European Journal of Pharmaceutics and Biopharmaceutics 170, 70-76, 2022 | 20 | 2022 |
Thrifty, rapid intestinal monolayers (TRIM) using caco-2 epithelial cells for oral drug delivery experiments NG Lamson, RL Ball, KC Fein, KA Whitehead Pharmaceutical Research 36, 1-12, 2019 | 15 | 2019 |
The strawberry-derived permeation enhancer pelargonidin enables oral protein delivery NG Lamson, KC Fein, JP Gleeson, AN Newby, S Xian, K Cochran, ... Proceedings of the National Academy of Sciences 119 (33), e2207829119, 2022 | 14 | 2022 |
Piperazine derivatives enhance epithelial cell monolayer permeability by increased cell force generation and loss of cadherin structures S Zheng, K Lavrenyuk, NG Lamson, KC Fein, KA Whitehead, KN Dahl ACS Biomaterials Science & Engineering 6 (1), 367-374, 2019 | 9 | 2019 |
Long‐term daily oral administration of intestinal permeation enhancers is safe and effective in mice KC Fein, JP Gleeson, K Cochran, NG Lamson, R Doerfler, JR Melamed, ... Bioengineering & Translational Medicine, e10342, 2022 | 8 | 2022 |
Placental drug transport and fetal exposure during pregnancy is determined by drug molecular size, chemistry, and conformation KC Fein, ML Arral, JS Kim, AN Newby, KA Whitehead Journal of Controlled Release 361, 29-39, 2023 | 5 | 2023 |
From farm to pharmacy: strawberry-enabled oral delivery of protein drugs NG Lamson, KC Fein, JP Gleeson, S Xian, A Newby, N Chaudhary, ... bioRxiv, 2020.03. 11.987461, 2020 | 3 | 2020 |
Profiling of mature stage human breastmilk cells identifies host-defense lactocyte sub-populations JP Gleeson, N Chaudhary, R Doerfler, KC Fein, T Hredzak-Showalter, ... bioRxiv, 2021.10. 04.463125, 2021 | 1 | 2021 |
Characterization and comparison of human and mouse milk cells R Doerfler, S Yerneni, A Newby, N Chaudhary, A Shu, K Fein, ... Plos one 19 (1), e0297821, 2024 | | 2024 |
Intestinal Permeation Enhancers Safely Enable the Oral Delivery of Macromolecules KC Fein Carnegie Mellon University, 2020 | | 2020 |
Rational Selection of Intestinal Permeation Enhancers for Oral Macromolecular Drug Delivery K Fein, K Whitehead 2019 AIChE Annual Meeting, 2019 | | 2019 |
Multiscale Structural Characterization of Epithelial Cell Monolayers Associated with the Addition of Permeability Enhancers for Enhancing Drug Delivery S Zheng, K Fein, N Lamson, KN Dahl, K Lavrenyuk, K Whitehead 2018 AIChE Annual Meeting, 2018 | | 2018 |
Proteins Covalently Conjugated to Phenylpiperazine-Containing Polymers Experience Selectively Enhanced Intestinal Epithelial Transport K Fein, C Cummings, H Murata, R Ball, A Russell, K Whitehead 2018 AIChE Annual Meeting, 2018 | | 2018 |
ATRP-Grown Protein-Polymer Conjugates Selectively Enhance Transepithelial Protein Transport C Cummings, K Fein, H Murata, R Ball, A Russell, K Whitehead 2017 AIChE Annual Meeting, 2017 | | 2017 |