Structure of Pumilio reveals similarity between RNA and peptide binding motifs TA Edwards, SE Pyle, RP Wharton, AK Aggarwal Cell 105 (2), 281-289, 2001 | 317 | 2001 |
Transcription corepressor CtBP is an NAD+-regulated dehydrogenase V Kumar, JE Carlson, KA Ohgi, TA Edwards, DW Rose, CR Escalante, ... Molecular cell 10 (4), 857-869, 2002 | 316 | 2002 |
ABC-F proteins mediate antibiotic resistance through ribosomal protection LKR Sharkey, TA Edwards, AJ O’Neill MBio 7 (2), 10.1128/mbio. 01975-15, 2016 | 237 | 2016 |
Crystal structure of the SF3 helicase from adeno-associated virus type 2 JA James, CR Escalante, M Yoon-Robarts, TA Edwards, RM Linden, ... Structure 11 (8), 1025-1035, 2003 | 154 | 2003 |
Crystal structure of the catalytic core of human DNA polymerase kappa SN Uljon, RE Johnson, TA Edwards, S Prakash, L Prakash, AK Aggarwal Structure 12 (8), 1395-1404, 2004 | 143 | 2004 |
Model of the brain tumor–Pumilio translation repressor complex TA Edwards, BD Wilkinson, RP Wharton, AK Aggarwal Genes & development 17 (20), 2508-2513, 2003 | 141 | 2003 |
Structure, function, and evolution of the Crimean-Congo hemorrhagic fever virus nucleocapsid protein SD Carter, R Surtees, CT Walter, A Ariza, É Bergeron, ST Nichol, ... Journal of virology 86 (20), 10914-10923, 2012 | 137 | 2012 |
ATP-driven remodeling of the linker domain in the dynein motor AJ Roberts, B Malkova, ML Walker, H Sakakibara, N Numata, T Kon, ... Structure 20 (10), 1670-1680, 2012 | 114 | 2012 |
Selective and potent proteomimetic inhibitors of intracellular protein–protein interactions A Barnard, K Long, HL Martin, JA Miles, TA Edwards, DC Tomlinson, ... Angewandte Chemie 127 (10), 3003-3008, 2015 | 111 | 2015 |
Oligobenzamide proteomimetic inhibitors of the p53–h DM2 protein–protein interaction JP Plante, T Burnley, B Malkova, ME Webb, SL Warriner, TA Edwards, ... Chemical Communications, 5091-5093, 2009 | 110 | 2009 |
Genetic Analysis of Physcomitrella patens Identifies ABSCISIC ACID NON-RESPONSIVE, a Regulator of ABA Responses Unique to Basal Land Plants and … SR Stevenson, Y Kamisugi, CH Trinh, J Schmutz, JW Jenkins, ... The Plant Cell 28 (6), 1310-1327, 2016 | 108 | 2016 |
Helix-mediated protein–protein interactions as targets for intervention using foldamers TA Edwards, AJ Wilson Amino acids 41, 743-754, 2011 | 107 | 2011 |
N-alkylated oligoamide α-helical proteomimetics F Campbell, JP Plante, TA Edwards, SL Warriner, AJ Wilson Organic & Biomolecular Chemistry 8 (10), 2344-2351, 2010 | 101 | 2010 |
Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization A Ariza, SJ Tanner, CT Walter, KC Dent, DA Shepherd, W Wu, ... Nucleic Acids Research 41 (11), 5912-5926, 2013 | 99 | 2013 |
Crystal structure of the essential transcription antiterminator M2-1 protein of human respiratory syncytial virus and implications of its phosphorylation SJ Tanner, A Ariza, CA Richard, HF Kyle, RL Dods, ML Blondot, W Wu, ... Proceedings of the National Academy of Sciences 111 (4), 1580-1585, 2014 | 95 | 2014 |
Predicting and experimentally validating hot-spot residues at protein–protein interfaces AA Ibarra, GJ Bartlett, Z Hegedus, S Dutt, F Hobor, KA Horner, ... ACS chemical biology 14 (10), 2252-2263, 2019 | 93 | 2019 |
Transforming growth factor-beta causes partial inhibition of interleukin 1—Stimulated cartilage degradation in vitro HJ Andrews, TA Edwards, TE Cawston, BL Hazleman Biochemical and biophysical research communications 162 (1), 144-150, 1989 | 86 | 1989 |
Hydrocarbon constrained peptides–understanding preorganisation and binding affinity JA Miles, DJ Yeo, P Rowell, S Rodriguez-Marin, CM Pask, SL Warriner, ... Chemical science 7 (6), 3694-3702, 2016 | 85 | 2016 |
Small‐Molecule Proteomimetic Inhibitors of the HIF‐1α–p300 Protein–Protein Interaction GM Burslem, HF Kyle, AL Breeze, TA Edwards, A Nelson, SL Warriner, ... ChemBioChem 15 (8), 1083-1087, 2014 | 76 | 2014 |
2-O-alkylated para-benzamide α-helix mimetics: The role of scaffold curvature V Azzarito, P Prabhakaran, AI Bartlett, NS Murphy, MJ Hardie, CA Kilner, ... Organic & Biomolecular Chemistry 10 (32), 6469-6472, 2012 | 75 | 2012 |