Classification and characterization of human endogenous retroviruses; mosaic forms are common L Vargiu, P Rodriguez-Tomé, GO Sperber, M Cadeddu, N Grandi, ... Retrovirology 13, 1-29, 2016 | 283 | 2016 |
Human endogenous retroviruses are ancient acquired elements still shaping innate immune responses N Grandi, E Tramontano Frontiers in immunology 9, 2039, 2018 | 270 | 2018 |
Geometrically and conformationally restrained cinnamoyl compounds as inhibitors of HIV-1 integrase: synthesis, biological evaluation, and molecular modeling M Artico, R Di Santo, R Costi, E Novellino, G Greco, S Massa, ... Journal of medicinal chemistry 41 (21), 3948-3960, 1998 | 238 | 1998 |
HERV envelope proteins: physiological role and pathogenic potential in cancer and autoimmunity N Grandi, E Tramontano Frontiers in microbiology 9, 462, 2018 | 210 | 2018 |
In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase. JW Mellors, GE Dutschman, GJ Im, E Tramontano, SR Winkler, YC Cheng Molecular pharmacology 41 (3), 446-451, 1992 | 202 | 1992 |
HIV‐1 reverse transcriptase still remains a new drug target: structure, function, classical inhibitors, and new inhibitors with innovative mechanisms of actions F Esposito, A Corona, E Tramontano Molecular biology international 2012 (1), 586401, 2012 | 162 | 2012 |
5-Alkyl-2-(alkylthio)-6-(2,6-dihalophenylmethyl)-3,4-dihydropyrimidin-4(3H)-ones: Novel Potent and Selective Dihydro-alkoxy-benzyl-oxopyrimidine Derivatives A Mai, M Artico, G Sbardella, S Massa, E Novellino, G Greco, AG Loi, ... Journal of Medicinal Chemistry 42 (4), 619-627, 1999 | 162 | 1999 |
Pyrazole-related nucleosides. Synthesis and antiviral/antitumor activity of some substituted pyrazole and pyrazolo [4, 3-d]-1, 2, 3-triazin-4-one nucleosides S Manfredini, R Bazzanini, PG Baraldi, M Guarneri, D Simoni, ... Journal of medicinal chemistry 35 (5), 917-924, 1992 | 160 | 1992 |
6-[1-(4-Fluorophenyl) methyl-1H-pyrrol-2-yl)]-2, 4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in … E Tramontano, F Esposito, R Badas, R Di Santo, R Costi, P La Colla Antiviral research 65 (2), 117-124, 2005 | 145 | 2005 |
Preparation and anti-HIV-1 activity of Thio Analogues of Dichydroalkoxybenzyloxopyrimidines A Mai, M Artico, G Sbardella, S Massa, AG Loi, E Tramontano, P Scano, ... Journal of medicinal chemistry 38 (17), 3258-3263, 1995 | 141 | 1995 |
Identification of inhibitors of SARS-CoV-2 3CL-pro enzymatic activity using a small molecule in vitro repurposing screen M Kuzikov, E Costanzi, J Reinshagen, F Esposito, L Vangeel, M Wolf, ... ACS pharmacology & translational science 4 (3), 1096-1110, 2021 | 125 | 2021 |
Strategies of highly pathogenic RNA viruses to block dsRNA detection by RIG-I-like receptors: hide, mask, hit L Zinzula, E Tramontano Antiviral research 100 (3), 615-635, 2013 | 111 | 2013 |
2, 6-Bis (3, 4, 5-trihydroxybenzylydene) derivatives of cyclohexanone: novel potent HIV-1 integrase inhibitors that prevent HIV-1 multiplication in cell-based assays R Costi, R Di Santo, M Artico, S Massa, R Ragno, R Loddo, M La Colla, ... Bioorganic & medicinal chemistry 12 (1), 199-215, 2004 | 111 | 2004 |
3, 4-Dihydro-2-alkoxy-6-benzyl-4-oxopyrimidines (DABOs): a new class of specific inhibitors of human immunodeficiency virus type 1 M Artico, S Massa, A Mai, ME Marongiu, G Piras, E Tramontano, ... Antiviral Chemistry and Chemotherapy 4 (6), 361-368, 1993 | 108 | 1993 |
HIV-1 reverse transcriptase inhibition by a dipyridodiazepinone derivative: BI-RG-587 T Enzo, C Yung-chi Biochemical pharmacology 43 (6), 1371-1376, 1992 | 102 | 1992 |
A single conservative amino acid substitution in the reverse transcriptase of human immunodeficiency virus-1 confers resistance to (+)-(5S)-4, 5, 6, 7-tetrahydro-5-methyl-6-(3 … JW Mellors, GJ Im, E Tramontano, SR Winkler, DJ Medina, GE Dutschman, ... Molecular pharmacology 43 (1), 11-16, 1993 | 94 | 1993 |
Anti-AIDS agents, 6. Salaspermic acid, an anti-HIV principle from Tripterycium wilfordii, and the structure-activity correlation with its related compounds KE Chen, Q Shi, Y Kashiwada, DC Zhang, CQ Hu, JQ Jin, H Nozaki, ... Journal of Natural Products 55 (3), 340-346, 1992 | 93 | 1992 |
Contribution of type W human endogenous retroviruses to the human genome: characterization of HERV-W proviral insertions and processed pseudogenes N Grandi, M Cadeddu, J Blomberg, E Tramontano Retrovirology 13, 1-25, 2016 | 90 | 2016 |
Hypericum hircinum L. components as new single-molecule inhibitors of both HIV-1 reverse transcriptase-associated DNA polymerase and ribonuclease H … F Esposito, C Sanna, C Del Vecchio, V Cannas, A Venditti, A Corona, ... Pathogens and disease 68 (3), 116-124, 2013 | 90 | 2013 |
New anti-human immunodeficiency virus type 1 6-aminoquinolones: mechanism of action C Parolin, B Gatto, C Del Vecchio, T Pecere, E Tramontano, V Cecchetti, ... Antimicrobial agents and chemotherapy 47 (3), 889-896, 2003 | 89 | 2003 |