G-quadruplex, Friend or Foe: The Role of the G-quartet in Anticancer Strategies J Carvalho, JL Mergny, GF Salgado, JA Queiroz, C Cruz Trends in molecular medicine 26 (9), 848-861, 2020 | 208 | 2020 |
Phosphatidylethanolamine enhances rhodopsin photoactivation and transducin binding in a solid supported lipid bilayer as determined using plasmon-waveguide resonance spectroscopy ID Alves, GFJ Salgado, Z Salamon, MF Brown, G Tollin, VJ Hruby Biophysical journal 88 (1), 198-210, 2005 | 133 | 2005 |
How the HIV-1 nucleocapsid protein binds and destabilises the (−) primer binding site during reverse transcription S Bourbigot, N Ramalanjaona, C Boudier, GFJ Salgado, BP Roques, ... Journal of molecular biology 383 (5), 1112-1128, 2008 | 122 | 2008 |
G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy GF Salgado, C Cazenave, A Kerkour, JL Mergny Chemical Science 6 (6), 3314-3320, 2015 | 105 | 2015 |
Aptamer-based targeted delivery of a G-quadruplex ligand in cervical cancer cells J Carvalho, A Paiva, MP Cabral Campello, A Paulo, JL Mergny, ... Scientific reports 9 (1), 7945, 2019 | 95 | 2019 |
Retinal dynamics underlie its switch from inverse agonist to agonist during rhodopsin activation AV Struts, GFJ Salgado, K Martínez-Mayorga, MF Brown Nature structural & molecular biology 18 (3), 392-394, 2011 | 88 | 2011 |
Deuterium NMR structure of retinal in the ground state of rhodopsin GFJ Salgado, AV Struts, K Tanaka, N Fujioka, K Nakanishi, MF Brown Biochemistry 43 (40), 12819-12828, 2004 | 81 | 2004 |
High-resolution three-dimensional NMR structure of the KRAS proto-oncogene promoter reveals key features of a G-quadruplex involved in transcriptional regulation A Kerkour, J Marquevielle, S Ivashchenko, LA Yatsunyk, JL Mergny, ... Journal of Biological Chemistry 292 (19), 8082-8091, 2017 | 74 | 2017 |
G-quadruplexes and their ligands: Biophysical methods to unravel G-quadruplex/ligand interactions T Santos, GF Salgado, EJ Cabrita, C Cruz Pharmaceuticals 14 (8), 769, 2021 | 73 | 2021 |
Structural analysis and dynamics of retinal chromophore in dark and meta I states of rhodopsin from 2H NMR of aligned membranes AV Struts, GFJ Salgado, K Tanaka, S Krane, K Nakanishi, MF Brown Journal of molecular biology 372 (1), 50-66, 2007 | 67 | 2007 |
Rhodopsin reconstituted into a planar-supported lipid bilayer retains photoactivity after cross-linking polymerization of lipid monomers V Subramaniam, ID Alves, GFJ Salgado, PW Lau, RJ Wysocki, Z Salamon, ... Journal of the American Chemical Society 127 (15), 5320-5321, 2005 | 64 | 2005 |
Solid-state 2H NMR relaxation illuminates functional dynamics of retinal cofactor in membrane activation of rhodopsin AV Struts, GFJ Salgado, MF Brown Proceedings of the National Academy of Sciences 108 (20), 8263-8268, 2011 | 60 | 2011 |
Solid-state 2H NMR spectroscopy of retinal proteins in aligned membranes MF Brown, MP Heyn, C Job, S Kim, S Moltke, K Nakanishi, AA Nevzorov, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1768 (12), 2979-3000, 2007 | 58 | 2007 |
Structure of two G-quadruplexes in equilibrium in the KRAS promoter J Marquevielle, C Robert, O Lagrabette, M Wahid, A Bourdoncle, LE Xodo, ... Nucleic Acids Research 48 (16), 9336-9345, 2020 | 49 | 2020 |
Solid-state 2H NMR structure of retinal in metarhodopsin I GFJ Salgado, AV Struts, K Tanaka, S Krane, K Nakanishi, MF Brown Journal of the American Chemical Society 128 (34), 11067-11071, 2006 | 49 | 2006 |
Fluorescent light-up acridine orange derivatives bind and stabilize KRAS-22RT G-quadruplex J Carvalho, E Pereira, J Marquevielle, MPC Campello, JL Mergny, ... Biochimie 144, 144-152, 2018 | 48 | 2018 |
Retinal dynamics during light activation of rhodopsin revealed by solid-state NMR spectroscopy MF Brown, GFJ Salgado, AV Struts Biochimica et Biophysica Acta (BBA)-Biomembranes 1798 (2), 177-193, 2010 | 44 | 2010 |
Aptamer selection by direct microfluidic recovery and surface plasmon resonance evaluation E Dausse, A Barré, A Aimé, A Groppi, A Rico, C Ainali, G Salgado, ... Biosensors and Bioelectronics 80, 418-425, 2016 | 43 | 2016 |
The interaction of antipsychotic drugs with lipids and subsequent lipid reorganization investigated using biophysical methods I Alves, G Staneva, C Tessier, GF Salgado, P Nuss Biochimica et Biophysica Acta (BBA)-Biomembranes 1808 (8), 2009-2018, 2011 | 39 | 2011 |
AS1411 derivatives as carriers of G-quadruplex ligands for cervical cancer cells J Figueiredo, J Lopes-Nunes, J Carvalho, F Antunes, M Ribeiro, ... International Journal of Pharmaceutics 568, 118511, 2019 | 35 | 2019 |