Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain–domain interactions Y Ke, CA Ng, MJ Hunter, SA Mann, J Heide, AP Hill, JI Vandenberg Biochemical Journal 454 (1), 69-77, 2013 | 47 | 2013 |
Axonal pathology in hPSC-based models of Parkinson’s disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus C Czaniecki, T Ryan, MG Stykel, J Drolet, J Heide, R Hallam, S Wood, ... Proceedings of the National Academy of Sciences 116 (28), 14280-14289, 2019 | 33 | 2019 |
Kinetics of drug interaction with the Kv11. 1 potassium channel AP Hill, MJ Perrin, J Heide, TJ Campbell, SA Mann, JI Vandenberg Molecular pharmacology 85 (5), 769-776, 2014 | 30 | 2014 |
The schizophrenia-associated Kv11. 1-3.1 isoform results in reduced current accumulation during repetitive brief depolarizations J Heide, SA Mann, JI Vandenberg Public Library of Science 7 (9), e45624, 2012 | 30 | 2012 |
Differential Response to Risperidone in Schizophrenia Patients by KCNH2 Genotype and Drug Metabolizer Status J Heide, F Zhang, KL Bigos, SA Mann, VJ Carr, C Shannon Weickert, ... American Journal of Psychiatry 173 (1), 53-59, 2016 | 26 | 2016 |
Recording of multiple ion current components and action potentials in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp SA Mann, J Heide, T Knott, R Airini, FB Epureanu, AF Deftu, AT Deftu, ... Journal of Pharmacological and Toxicological Methods 100, 106599, 2019 | 20 | 2019 |
Expression of KCNH2-3.1 mRNA is increased in small neurons in the dorsolateral prefrontal cortex in patients with schizophrenia J Heide, JI Vandenberg, CS Weickert The European Journal of Psychiatry 29 (2), 85-103, 2015 | 5 | 2015 |
Using onset-of-block kinetic analysis of hERG1 current with a markov model to improve in silico proarrhythmogenic risk prediction BP Amuzescu, T Knott, SA Mann, J Knuepling, R Airini, FB Epureanu, ... Biophysical Journal 118 (3), 265a, 2020 | 1 | 2020 |
Development of a new CiPA-compliant MOA in vitro assay on stem cell-derived cardiomyocytes including automated data analysis and model parameter optimization S Mann, J Heide, R Airini, F Epureanu, A Deftu, AT Deftu, BM Radu, ... Journal of Pharmacological and Toxicological Methods 99, 106595, 2019 | | 2019 |
Role of KCNH2 potassium channels in the pathogenesis of schizophrenia J Heide UNSW Sydney, 2013 | | 2013 |
CHARACTERIZATION OF A NOVEL HERG POTASSIUM CHANNEL ISOFORM UPREGULATED IN SCHIZOPHRENIA PATIENTS J Heide, SA Mann, JI Vandenberg AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY 44, A51-A51, 2010 | | 2010 |
Measuring multiple ion current components in human induced pluripotent stem cell-derived cardiomyocytes via automated patch-clamp S Mann, J Heide, B Radu, B Amuzescu, T Knott J Gen Physiol 125 (3), 305-26, 2005 | | 2005 |