Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography MJ Dalby, MO Riehle, SJ Yarwood, CDW Wilkinson, ASG Curtis Experimental cell research 284 (2), 272-280, 2003 | 516 | 2003 |
The RACK1 scaffold protein: a dynamic cog in cell response mechanisms A McCahill, J Warwicker, GB Bolger, MD Houslay, SJ Yarwood Molecular pharmacology 62 (6), 1261-1273, 2002 | 456 | 2002 |
Increasing fibroblast response to materials using nanotopography: morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands MJ Dalby, SJ Yarwood, MO Riehle, HJH Johnstone, S Affrossman, ... Experimental cell research 276 (1), 1-9, 2002 | 435 | 2002 |
The RACK1 signaling scaffold protein selectively interacts with the cAMP-specific phosphodiesterase PDE4D5 isoform SJ Yarwood, MR Steele, G Scotland, MD Houslay, GB Bolger Journal of Biological Chemistry 274 (21), 14909-14917, 1999 | 355 | 1999 |
The MAP kinase ERK2 inhibits the cyclic AMP-specific phosphodiesterase HSPDE4D3 by phosphorylating it at Ser579 R Hoffmann, GS Baillie, SJ MacKenzie, SJ Yarwood, MD Houslay The EMBO journal 18 (4), 893-903, 1999 | 323 | 1999 |
Effect of cellular uptake of gelatin nanoparticles on adhesion, morphology and cytoskeleton organisation of human fibroblasts AK Gupta, M Gupta, SJ Yarwood, ASG Curtis Journal of Controlled Release 95 (2), 197-207, 2004 | 234 | 2004 |
EPAC proteins transduce diverse cellular actions of cAMP G Borland, BO Smith, SJ Yarwood British journal of pharmacology 158 (1), 70-86, 2009 | 195 | 2009 |
Association with the SRC family tyrosyl kinase LYN triggers a conformational change in the catalytic region of human cAMP-specific phosphodiesterase HSPDE4A4B: consequences for … I McPhee, SJ Yarwood, G Scotland, E Huston, MB Beard, AH Ross, ... Journal of Biological Chemistry 274 (17), 11796-11810, 1999 | 137 | 1999 |
Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms SC Chen, R Brooks, J Houskeeper, SK Bremner, J Dunlop, B Viollet, ... Molecular and cellular endocrinology 440, 57-68, 2017 | 126 | 2017 |
Dynamic surfaces for the study of mesenchymal stem cell growth through adhesion regulation JN Roberts, JK Sahoo, LE McNamara, KV Burgess, J Yang, EV Alakpa, ... ACS nano 10 (7), 6667-6679, 2016 | 101 | 2016 |
Identification of CCAAT/enhancer-binding proteins as exchange protein activated by cAMP-activated transcription factors that mediate the induction of the SOCS-3 gene SJ Yarwood, G Borland, WA Sands, TM Palmer Journal of Biological Chemistry 283 (11), 6843-6853, 2008 | 94 | 2008 |
The future of EPAC-targeted therapies: agonism versus antagonism E Parnell, TM Palmer, SJ Yarwood Trends in pharmacological sciences 36 (4), 203-214, 2015 | 90 | 2015 |
Growth hormone-dependent differentiation of 3T3-F442A preadipocytes requires Janus kinase/signal transducer and activator of transcription but not mitogen-activated protein … SJ Yarwood, EM Sale, GJ Sale, MD Houslay, E Kilgour, NG Anderson Journal of Biological Chemistry 274 (13), 8662-8668, 1999 | 82 | 1999 |
Extracellular matrix composition determines the transcriptional response to epidermal growth factor receptor activation SJ Yarwood, JR Woodgett Proceedings of the National Academy of Sciences 98 (8), 4472-4477, 2001 | 81 | 2001 |
Stimulation of p70S6 kinase via a growth hormone-controlled phosphatidylinositol 3-kinase pathway leads to the activation of a PDE4A cyclic AMP-specific phosphodiesterase in … SJ MacKenzie, SJ Yarwood, AH Peden, GB Bolger, RG Vernon, ... Proceedings of the National Academy of Sciences 95 (7), 3549-3554, 1998 | 81 | 1998 |
Regulation of the inflammatory response of vascular endothelial cells by EPAC1 E Parnell, BO Smith, TM Palmer, A Terrin, M Zaccolo, SJ Yarwood British journal of pharmacology 166 (2), 434-446, 2012 | 73 | 2012 |
The effect of the RACK1 signalling protein on the regulation of cell adhesion and cell contact guidance on nanometric grooves MJ Dalby, A Hart, SJ Yarwood Biomaterials 29 (3), 282-289, 2008 | 68 | 2008 |
Activation of protein kinase Cα by EPAC1 is required for the ERK-and CCAAT/enhancer-binding protein β-dependent induction of the SOCS-3 gene by cyclic AMP in COS1 cells G Borland, RJ Bird, TM Palmer, SJ Yarwood Journal of Biological Chemistry 284 (26), 17391-17403, 2009 | 64 | 2009 |
Microtubule-associated protein 1B-light chain 1 enhances activation of Rap1 by exchange protein activated by cyclic AMP but not intracellular targeting G Borland, M Gupta, MM Magiera, CJ Rundell, S Fuld, SJ Yarwood Molecular pharmacology 69 (1), 374-384, 2006 | 62 | 2006 |
Nanotopography controls cell cycle changes involved with skeletal stem cell self-renewal and multipotency LCY Lee, N Gadegaard, MC De Andrés, LA Turner, KV Burgess, ... Biomaterials 116, 10-20, 2017 | 59 | 2017 |