| Metabolic gatekeeper function of B-lymphoid transcription factors LN Chan, Z Chen, D Braas, JW Lee, G Xiao, H Geng, KN Cosgun, C Hurtz, ... Nature 542 (7642), 479-483, 2017 | 224 | 2017 |
| Kit regulates HSC engraftment across the human-mouse species barrier KN Cosgun, S Rahmig, N Mende, S Reinke, I Hauber, C Schäfer, ... Cell stem cell 15 (2), 227-238, 2014 | 195 | 2014 |
| PTEN opposes negative selection and enables oncogenic transformation of pre-B cells S Shojaee, LN Chan, M Buchner, V Cazzaniga, KN Cosgun, H Geng, ... Nature medicine 22 (4), 379-387, 2016 | 128 | 2016 |
| B-cell-specific diversion of glucose carbon utilization reveals a unique vulnerability in B cell malignancies G Xiao, LN Chan, L Klemm, D Braas, Z Chen, H Geng, QC Zhang, ... Cell 173 (2), 470-484. e18, 2018 | 113 | 2018 |
| Clonal expansion capacity defines two consecutive developmental stages of long-term hematopoietic stem cells T Grinenko, K Arndt, M Portz, N Mende, M Günther, KN Cosgun, ... Journal of Experimental Medicine 211 (2), 209-215, 2014 | 97 | 2014 |
| IFITM3 functions as a PIP3 scaffold to amplify PI3K signalling in B cells J Lee, ME Robinson, N Ma, D Artadji, MA Ahmed, G Xiao, T Sadras, ... Nature 588 (7838), 491-497, 2020 | 77 | 2020 |
| Signalling input from divergent pathways subverts B cell transformation LN Chan, MA Murakami, ME Robinson, R Caeser, T Sadras, J Lee, ... Nature 583 (7818), 845-851, 2020 | 52 | 2020 |
| In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice M von Bonin, M Wermke, KN Cosgun, C Thiede, M Bornhauser, ... PLoS One 8 (4), e60680, 2013 | 35 | 2013 |
| Developmental partitioning of SYK and ZAP70 prevents autoimmunity and cancer T Sadras, M Martin, K Kume, ME Robinson, S Saravanakumar, G Lenz, ... Molecular cell 81 (10), 2094-2111. e9, 2021 | 29 | 2021 |
| Engineered dendritic cells from cord blood and adult blood accelerate effector T cell immune reconstitution against HCMV A Daenthanasanmak, G Salguero, BS Sundarasetty, C Waskow, ... Molecular Therapy Methods & Clinical Development 2, 2015 | 28 | 2015 |
| PON2 subverts metabolic gatekeeper functions in B cells to promote leukemogenesis L Pan, C Hong, LN Chan, G Xiao, P Malvi, ME Robinson, H Geng, ... Proceedings of the National Academy of Sciences 118 (7), e2016553118, 2021 | 13 | 2021 |
| Lgr5 functions as negative regulator of Wnt signaling in B cells and is critical for self-renewal of normal and transformed B cells KNN Cosgun, A Hecht, X Yang, M Mangolini, A Aghajanirefah, Z Chen, ... Blood 130, 3989, 2017 | 5 | 2017 |
| Lgr5-mediated restraint of β-catenin is essential for B-lymphopoiesis and leukemia-initiation KN Cosgun, ME Robinson, G Deb, X Yang, G Xiao, T Sadras, J Lee, ... bioRxiv, 2020.03. 12.989277, 2020 | 3 | 2020 |
| Cooperation between SYK and ZAP70 kinases as a driver of oncogenic BCR-signaling in B-cell malignancies T Sadras, J Cutler, J Aguade-Gorgorio, Z Chen, KN Cosgun, A Pandey, ... Blood 132, 3922, 2018 | 3 | 2018 |
| Lgr5 enables positive B-cell selection and tumor-initiation in B-cell malignancies KN Cosgun, G Deb, X Yang, G Xiao, T Sadras, F Auer, J Lee, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 2 | 2018 |
| IFITM3-Mediated Regulation of Cell Membrane Dynamics Is Essential for Malignant B-Cell Transformation JW Lee, H Geng, DS Dinson, G Xiao, KN Cosgun, LN Chan, Z Chen, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 2 | 2018 |
| CD25 Enables Oncogenic BCR Signaling and Represents a Therapeutic Target in Refractory B Cell Malignancies JW Lee, H Geng, Z Chen, L Klemm, KN Cosgun, G Xiao, B Masouleh, ... Blood 128 (22), 4088, 2016 | 2 | 2016 |
| Dynamic phosphatase-recruitment controls B-cell selection and oncogenic signaling J Lee, ME Robinson, R Sun, K Kume, N Ma, KN Cosgun, LN Chan, ... bioRxiv, 2023.03. 13.532151, 2023 | 1 | 2023 |
| Targeted engagement of β-catenin-Ikaros complexes in refractory B-cell malignancies KN Cosgun, H Jumaa, ME Robinson, KM Kistner, L Xu, G Xiao, LN Chan, ... bioRxiv, 2023.03. 13.532152, 2023 | 1 | 2023 |
| Divergent MYC-and BCL6-Driven Metabolic Programs Enable Dynamic Regulation of Cell Biomass in B-Cell Malignancies K Kume, Z Chen, LN Chan, ME Robinson, E Leveille, J Lee, KN Cosgun, ... Blood 140 (Supplement 1), 5900-5901, 2022 | 1 | 2022 |
