Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing MS Stark, SL Woods, MG Gartside, VF Bonazzi, K Dutton-Regester, ... Nature genetics 44 (2), 165-169, 2012 | 217 | 2012 |
A quantitative map of the liver mitochondrial phosphoproteome reveals posttranslational control of ketogenesis PA Grimsrud, JJ Carson, AS Hebert, SL Hubler, NM Niemi, DJ Bailey, ... Cell metabolism 16 (5), 672-683, 2012 | 179 | 2012 |
Classification of T-cell activation via autofluorescence lifetime imaging AJ Walsh, KP Mueller, K Tweed, I Jones, CM Walsh, NJ Piscopo, ... Nature biomedical engineering 5 (1), 77-88, 2021 | 122 | 2021 |
Birt-Hogg-Dube renal tumors are genetically distinct from other renal neoplasias and are associated with up-regulation of mitochondrial gene expression JA Klomp, D Petillo, NM Niemi, KJ Dykema, J Chen, XJ Yang, A Sääf, ... BMC medical genomics 3, 1-12, 2010 | 101 | 2010 |
A mitochondrial RNAi screen defines cellular bioenergetic determinants and identifies an adenylate kinase as a key regulator of ATP levels NJ Lanning, BD Looyenga, AL Kauffman, NM Niemi, J Sudderth, ... Cell reports 7 (3), 907-917, 2014 | 94 | 2014 |
Down-regulation of class II phosphoinositide 3-kinase α expression below a critical threshold induces apoptotic cell death W Elis, E Triantafellow, NM Wolters, KR Sian, G Caponigro, J Borawski, ... Molecular Cancer Research 6 (4), 614-623, 2008 | 67 | 2008 |
Quantitative shotgun proteome analysis by direct infusion JG Meyer, NM Niemi, DJ Pagliarini, JJ Coon Nature methods 17 (12), 1222-1228, 2020 | 60 | 2020 |
A survey-based analysis of the academic job market JD Fernandes, S Sarabipour, CT Smith, NM Niemi, NM Jadavji, AJ Kozik, ... Elife 9, e54097, 2020 | 55 | 2020 |
Ptc7p dephosphorylates select mitochondrial proteins to enhance metabolic function X Guo, NM Niemi, PD Hutchins, SGF Condon, A Jochem, A Ulbrich, ... Cell reports 18 (2), 307-313, 2017 | 53 | 2017 |
Mitochondrial phosphorylation in apoptosis: flipping the death switch NM Niemi, JP MacKeigan Antioxidants & redox signaling 19 (6), 572-582, 2013 | 52 | 2013 |
MK-STYX, a catalytically inactive phosphatase regulating mitochondrially dependent apoptosis NM Niemi, NJ Lanning, JA Klomp, SW Tait, Y Xu, KJ Dykema, LO Murphy, ... Molecular and cellular biology 31 (7), 1357-1368, 2011 | 50 | 2011 |
EGFR ligand switch in late stage prostate cancer contributes to changes in cell signaling and bone remodeling AM DeHaan, NM Wolters, ET Keller, KMW Ignatoski The Prostate 69 (5), 528-537, 2009 | 50 | 2009 |
Pptc7 is an essential phosphatase for promoting mammalian mitochondrial metabolism and biogenesis NM Niemi, GM Wilson, KA Overmyer, FN Vögtle, L Myketin, DC Lohman, ... Nature communications 10 (1), 3197, 2019 | 48 | 2019 |
From sequence to function: using RNAi to elucidate mechanisms of human disease NM Wolters, JP MacKeigan Cell Death & Differentiation 15 (5), 809-819, 2008 | 48 | 2008 |
Downregulation of the mitochondrial phosphatase PTPMT1 is sufficient to promote cancer cell death NM Niemi, NJ Lanning, LM Westrate, JP MacKeigan PloS one 8 (1), e53803, 2013 | 37 | 2013 |
The pseudophosphatase MK-STYX physically and genetically interacts with the mitochondrial phosphatase PTPMT1 NM Niemi, JL Sacoman, LM Westrate, LA Gaither, NJ Lanning, KR Martin, ... PLoS One 9 (4), e93896, 2014 | 33 | 2014 |
Integrative proteomics and biochemical analyses define Ptc6p as the Saccharomyces cerevisiae pyruvate dehydrogenase phosphatase X Guo, NM Niemi, JJ Coon, DJ Pagliarini Journal of Biological Chemistry 292 (28), 11751-11759, 2017 | 28 | 2017 |
Mitochondrial pyruvate carrier inhibition initiates metabolic crosstalk to stimulate branched chain amino acid catabolism D Ferguson, SJ Eichler, NKH Yiew, JR Colca, K Cho, GJ Patti, TM Shew, ... Molecular metabolism 70, 101694, 2023 | 25 | 2023 |
The extensive and functionally uncharacterized mitochondrial phosphoproteome NM Niemi, DJ Pagliarini Journal of Biological Chemistry 297 (1), 2021 | 24 | 2021 |
Label-free Method for Classification of T cell Activation AJ Walsh, K Mueller, I Jones, CM Walsh, N Piscopo, NN Niemi, ... bioRxiv, 536813, 2019 | 16 | 2019 |