Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema ZH Chen, HC Lam, Y Jin, HP Kim, J Cao, SJ Lee, E Ifedigbo, ... Proceedings of the National Academy of Sciences 107 (44), 18880-18885, 2010 | 389 | 2010 |
Mitochondrial iron chelation ameliorates cigarette smoke–induced bronchitis and emphysema in mice SM Cloonan, K Glass, ME Laucho-Contreras, AR Bhashyam, M Cervo, ... Nature medicine 22 (2), 163-174, 2016 | 227 | 2016 |
Mechanics, nonlinearity, and failure strength of lung tissue in a mouse model of emphysema: possible role of collagen remodeling S Ito, EP Ingenito, KK Brewer, LD Black, H Parameswaran, KR Lutchen, ... Journal of applied physiology 98 (2), 503-511, 2005 | 171 | 2005 |
Alveolar macrophage activation and an emphysema-like phenotype in adiponectin-deficient mice R Summer, FF Little, N Ouchi, Y Takemura, T Aprahamian, D Dwyer, ... American Journal of Physiology-Lung Cellular and Molecular Physiology 294 (6 …, 2008 | 162 | 2008 |
Tissue heterogeneity in the mouse lung: effects of elastase treatment S Ito, EP Ingenito, SP Arold, H Parameswaran, NT Tgavalekos, ... Journal of applied physiology 97 (1), 204-212, 2004 | 141 | 2004 |
Quantitative characterization of airspace enlargement in emphysema H Parameswaran, A Majumdar, S Ito, AM Alencar, B Suki Journal of applied physiology 100 (1), 186-193, 2006 | 135 | 2006 |
Emphysema and mechanical stress-induced lung remodeling B Suki, S Sato, H Parameswaran, MV Szabari, A Takahashi, ... Physiology 28 (6), 404-413, 2013 | 95 | 2013 |
Microtubule dynamics regulate cyclic stretch-induced cell alignment in human airway smooth muscle cells M Morioka, H Parameswaran, K Naruse, M Kondo, M Sokabe, ... PloS one 6 (10), e26384, 2011 | 92 | 2011 |
Three-dimensional measurement of alveolar airspace volumes in normal and emphysematous lungs using micro-CT H Parameswaran, E Bartolák-Suki, H Hamakawa, A Majumdar, PG Allen, ... Journal of Applied Physiology 107 (2), 583-592, 2009 | 84 | 2009 |
Structure–function relations in an elastase-induced mouse model of emphysema H Hamakawa, E Bartolák-Suki, H Parameswaran, A Majumdar, ... American journal of respiratory cell and molecular biology 45 (3), 517-524, 2011 | 74 | 2011 |
Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces S Ito, E Bartolák-Suki, JM Shipley, H Parameswaran, A Majumdar, B Suki American journal of respiratory cell and molecular biology 34 (6), 688-694, 2006 | 70 | 2006 |
Fluctuation-driven mechanotransduction regulates mitochondrial-network structure and function E Bartolák-Suki, J Imsirovic, H Parameswaran, TJ Wellman, N Martinez, ... Nature materials 14 (10), 1049-1057, 2015 | 69 | 2015 |
Extracellular matrix stiffness regulates human airway smooth muscle contraction by altering the cell-cell coupling SR Polio, SE Stasiak, RR Jamieson, JL Balestrini, R Krishnan, ... Scientific reports 9 (1), 9564, 2019 | 65 | 2019 |
Mechanical forces regulate elastase activity and binding site availability in lung elastin R Jesudason, S Sato, H Parameswaran, AD Araujo, A Majumdar, ... Biophysical journal 99 (9), 3076-3083, 2010 | 60 | 2010 |
Proteoglycans maintain lung stability in an elastase-treated mouse model of emphysema A Takahashi, A Majumdar, H Parameswaran, E Bartolák-Suki, B Suki American journal of respiratory cell and molecular biology 51 (1), 26-33, 2014 | 50 | 2014 |
Linking microscopic spatial patterns of tissue destruction in emphysema to macroscopic decline in stiffness using a 3D computational model H Parameswaran, A Majumdar, B Suki PLoS computational biology 7 (4), e1001125, 2011 | 48 | 2011 |
Can tidal breathing with deep inspirations of intact airways create sustained bronchoprotection or bronchodilation? BC Harvey, H Parameswaran, KR Lutchen Journal of applied physiology 115 (4), 436-445, 2013 | 46 | 2013 |
Mechanical failure, stress redistribution, elastase activity and binding site availability on elastin during the progression of emphysema B Suki, R Jesudason, S Sato, H Parameswaran, AD Araujo, A Majumdar, ... Pulmonary pharmacology & therapeutics 25 (4), 268-275, 2012 | 46 | 2012 |
A computational model of the response of adherent cells to stretch and changes in substrate stiffness H Parameswaran, KR Lutchen, B Suki Journal of applied physiology 116 (7), 825-834, 2014 | 45 | 2014 |
Mechanical forces accelerate collagen digestion by bacterial collagenase in lung tissue strips E Yi, S Sato, A Takahashi, H Parameswaran, TA Blute, E Bartolák-Suki, ... Frontiers in physiology 7, 287, 2016 | 41 | 2016 |