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Christopher B. Mulholland
Christopher B. Mulholland
在 bio.lmu.de 的电子邮件经过验证
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DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex
G Gasparoni, S Bultmann, P Lutsik, TFJ Kraus, S Sordon, J Vlcek, ...
Epigenetics & chromatin 11, 1-19, 2018
2022018
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation
A Nishiyama, CB Mulholland, S Bultmann, S Kori, A Endo, Y Saeki, W Qin, ...
Nature communications 11 (1), 1222, 2020
1092020
Critical role of the UBL domain in stimulating the E3 ubiquitin ligase activity of UHRF1 toward chromatin
BM Foster, P Stolz, CB Mulholland, A Montoya, H Kramer, S Bultmann, ...
Molecular cell 72 (4), 739-752. e9, 2018
822018
Spatial organization of transcribed eukaryotic genes
S Leidescher, J Ribisel, S Ullrich, Y Feodorova, E Hildebrand, A Galitsyna, ...
Nature cell biology 24 (3), 327-339, 2022
812022
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals
CB Mulholland, A Nishiyama, J Ryan, R Nakamura, M Yiğit, IM Glück, ...
Nature communications 11 (1), 1-24, 2020
562020
A modular open platform for systematic functional studies under physiological conditions
CB Mulholland, M Smets, E Schmidtmann, S Leidescher, Y Markaki, ...
Nucleic Acids Research 43 (17), e112-e112, 2015
492015
Ubiquitome analysis reveals PCNA-associated factor 15 (PAF15) as a specific ubiquitination target of UHRF1 in embryonic stem cells
E Karg, M Smets, J Ryan, I Forné, W Qin, CB Mulholland, G Kalideris, ...
Journal of molecular biology 429 (24), 3814-3824, 2017
462017
Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis
C Wenk, AK Garz, S Grath, C Huberle, D Witham, M Weickert, ...
Blood advances 2 (23), 3447-3461, 2018
442018
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation
P Stolz, AS Mantero, A Tvardovskiy, E Ugur, LE Wange, CB Mulholland, ...
Nucleic Acids Research 50 (15), 8491-8511, 2022
242022
Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency
CB Mulholland, FR Traube, E Ugur, E Parsa, EM Eckl, M Schönung, ...
Scientific reports 10 (1), 12066, 2020
222020
Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger
K Hata, N Kobayashi, K Sugimura, W Qin, D Haxholli, Y Chiba, S Yoshimi, ...
Nucleic Acids Research 50 (21), 12527-12542, 2022
102022
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency
W Qin, E Ugur, CB Mulholland, S Bultmann, I Solovei, M Modic, M Smets, ...
Nucleic Acids Research 49 (13), 7406-7423, 2021
102021
TET1 drives global DNA demethylation via DPPA3-mediated inhibition of maintenance methylation
CB Mulholland, J Ryan, W Qin, MD Bartoschek, FR Traube, E Parsa, ...
22018
Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation
M Modic, IR de Los Mozos, S Steinhauser, E van Genderen, S Schirge, ...
bioRxiv, 2021.03. 15.433780, 2021
12021
Azacitidine Directly Acts on the Mesenchymal Stromal Cell Compartment in Myelodysplastic Syndromes to Alter Niche Function and Suppress Malignant Hematopoeitic Stem/Progenitor …
C Wenk, AK Garz, C Huberle, S Grath, D Witham, M Weickert, ...
Blood 130, 1683, 2017
12017
Embryonic lumenogenesis is controlled by selective mRNA decay triggered by LIN28A relocation
M Modic, IR Mozos, S Schirge, V Bergant, T Klobucar, C Mulholland, ...
FEBS OPEN BIO 11, 334-335, 2021
2021
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive demethylation in mammals
CB Mulholland, A Nishiyama, J Ryan, R Nakamura, M Yiğit, IM Glueck, ...
bioRxiv, 321604, 2020
2020
Live-cell imaging reveals dynamics and distribution of Tet1 in mouse embryonic stem cells
J Ryan, CB Mulholland, E Schmidtmann, H Leonhardt
Molecular Biology of the Cell, 2016
2016
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