DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex G Gasparoni, S Bultmann, P Lutsik, TFJ Kraus, S Sordon, J Vlcek, ... Epigenetics & chromatin 11, 1-19, 2018 | 202 | 2018 |
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation A Nishiyama, CB Mulholland, S Bultmann, S Kori, A Endo, Y Saeki, W Qin, ... Nature communications 11 (1), 1222, 2020 | 109 | 2020 |
Critical role of the UBL domain in stimulating the E3 ubiquitin ligase activity of UHRF1 toward chromatin BM Foster, P Stolz, CB Mulholland, A Montoya, H Kramer, S Bultmann, ... Molecular cell 72 (4), 739-752. e9, 2018 | 82 | 2018 |
Spatial organization of transcribed eukaryotic genes S Leidescher, J Ribisel, S Ullrich, Y Feodorova, E Hildebrand, A Galitsyna, ... Nature cell biology 24 (3), 327-339, 2022 | 81 | 2022 |
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive DNA demethylation in mammals CB Mulholland, A Nishiyama, J Ryan, R Nakamura, M Yiğit, IM Glück, ... Nature communications 11 (1), 1-24, 2020 | 56 | 2020 |
A modular open platform for systematic functional studies under physiological conditions CB Mulholland, M Smets, E Schmidtmann, S Leidescher, Y Markaki, ... Nucleic Acids Research 43 (17), e112-e112, 2015 | 49 | 2015 |
Ubiquitome analysis reveals PCNA-associated factor 15 (PAF15) as a specific ubiquitination target of UHRF1 in embryonic stem cells E Karg, M Smets, J Ryan, I Forné, W Qin, CB Mulholland, G Kalideris, ... Journal of molecular biology 429 (24), 3814-3824, 2017 | 46 | 2017 |
Direct modulation of the bone marrow mesenchymal stromal cell compartment by azacitidine enhances healthy hematopoiesis C Wenk, AK Garz, S Grath, C Huberle, D Witham, M Weickert, ... Blood advances 2 (23), 3447-3461, 2018 | 44 | 2018 |
TET1 regulates gene expression and repression of endogenous retroviruses independent of DNA demethylation P Stolz, AS Mantero, A Tvardovskiy, E Ugur, LE Wange, CB Mulholland, ... Nucleic Acids Research 50 (15), 8491-8511, 2022 | 24 | 2022 |
Distinct and stage-specific contributions of TET1 and TET2 to stepwise cytosine oxidation in the transition from naive to primed pluripotency CB Mulholland, FR Traube, E Ugur, E Parsa, EM Eckl, M Schönung, ... Scientific reports 10 (1), 12066, 2020 | 22 | 2020 |
Structural basis for the unique multifaceted interaction of DPPA3 with the UHRF1 PHD finger K Hata, N Kobayashi, K Sugimura, W Qin, D Haxholli, Y Chiba, S Yoshimi, ... Nucleic Acids Research 50 (21), 12527-12542, 2022 | 10 | 2022 |
Phosphorylation of the HP1β hinge region sequesters KAP1 in heterochromatin and promotes the exit from naïve pluripotency W Qin, E Ugur, CB Mulholland, S Bultmann, I Solovei, M Modic, M Smets, ... Nucleic Acids Research 49 (13), 7406-7423, 2021 | 10 | 2021 |
TET1 drives global DNA demethylation via DPPA3-mediated inhibition of maintenance methylation CB Mulholland, J Ryan, W Qin, MD Bartoschek, FR Traube, E Parsa, ... | 2 | 2018 |
Epiblast morphogenesis is controlled by selective mRNA decay triggered by LIN28A relocation M Modic, IR de Los Mozos, S Steinhauser, E van Genderen, S Schirge, ... bioRxiv, 2021.03. 15.433780, 2021 | 1 | 2021 |
Azacitidine Directly Acts on the Mesenchymal Stromal Cell Compartment in Myelodysplastic Syndromes to Alter Niche Function and Suppress Malignant Hematopoeitic Stem/Progenitor … C Wenk, AK Garz, C Huberle, S Grath, D Witham, M Weickert, ... Blood 130, 1683, 2017 | 1 | 2017 |
Embryonic lumenogenesis is controlled by selective mRNA decay triggered by LIN28A relocation M Modic, IR Mozos, S Schirge, V Bergant, T Klobucar, C Mulholland, ... FEBS OPEN BIO 11, 334-335, 2021 | | 2021 |
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive demethylation in mammals CB Mulholland, A Nishiyama, J Ryan, R Nakamura, M Yiğit, IM Glueck, ... bioRxiv, 321604, 2020 | | 2020 |
Live-cell imaging reveals dynamics and distribution of Tet1 in mouse embryonic stem cells J Ryan, CB Mulholland, E Schmidtmann, H Leonhardt Molecular Biology of the Cell, 2016 | | 2016 |