Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate MP Hall, J Unch, BF Binkowski, MP Valley, BL Butler, MG Wood, P Otto, ... ACS chemical biology 7 (11), 1848-1857, 2012 | 1551 | 2012 |
Quantitative, wide-spectrum kinase profiling in live cells for assessing the effect of cellular ATP on target engagement JD Vasta, CR Corona, J Wilkinson, CA Zimprich, JR Hartnett, MR Ingold, ... Cell chemical biology 25 (2), 206-214. e11, 2018 | 221 | 2018 |
Bioluminescent, nonlytic, real-time cell viability assay and use in inhibitor screening SJ Duellman, W Zhou, P Meisenheimer, G Vidugiris, JJ Cali, P Gautam, ... Assay and drug development technologies 13 (8), 456-465, 2015 | 103 | 2015 |
Quantifying CDK inhibitor selectivity in live cells CI Wells, JD Vasta, CR Corona, J Wilkinson, CA Zimprich, MR Ingold, ... Nature communications 11 (1), 2743, 2020 | 87 | 2020 |
Oplophorus-derived luciferases, novel coelenterazine substrates, and methods of use B Binkowski, LP Encell, M Hall, MB Robers, MR Slater, KV Wood, ... US Patent 8,669,103, 2014 | 85 | 2014 |
Novel heterocyclic analogues of firefly luciferin CC Woodroofe, PL Meisenheimer, DH Klaubert, Y Kovic, JC Rosenberg, ... Biochemistry 51 (49), 9807-9813, 2012 | 80 | 2012 |
Synthesis and biological evaluation of tryptamines found in hallucinogenic mushrooms: norbaeocystin, baeocystin, norpsilocin, and aeruginascin AM Sherwood, AL Halberstadt, AK Klein, JD McCorvy, KW Kaylo, ... Journal of natural products 83 (2), 461-467, 2020 | 77 | 2020 |
Engineered luciferase reporter from a deep sea shrimp utilizing a novel imidazopyrazinone substrate. ACS Chem Biol 7: 1848–1857 MP Hall, J Unch, BF Binkowski, MP Valley, BL Butler, MG Wood, P Otto, ... | 70 | 2012 |
Imidazo [1, 2-α] pyrazine derivatives DH Klaubert, P Meisenheimer, J Unch US Patent 8,809,529, 2014 | 69 | 2014 |
N-Alkylated 6′-aminoluciferins are bioluminescent substrates for Ultra-Glo and QuantiLum luciferase: new potential scaffolds for bioluminescent assays CC Woodroofe, JW Shultz, MG Wood, J Osterman, JJ Cali, WJ Daily, ... Biochemistry 47 (39), 10383-10393, 2008 | 68 | 2008 |
Mechanistic studies of the 5-iodouracil chromophore relevant to its use in nucleoprotein photo-cross-linking CL Norris, PL Meisenheimer, TH Koch Journal of the American Chemical Society 118 (24), 5796-5803, 1996 | 65 | 1996 |
Luminogenic and fluorogenic compounds and methods to detect molecules or conditions JJ Cali, W Daily, E Hawkins, D Klaubert, J Liu, P Meisenheimer, M Scurria, ... US Patent 7,951,550, 2011 | 58 | 2011 |
High yield photocrosslinking of a 5-iodocytidine (IC) substituted RNA to its associated protein KM Meisenheimer, PL Meisenheimer, MC Willis, TH Koch Nucleic acids research 24 (5), 981-982, 1996 | 55 | 1996 |
Improving protein array performance: focus on washing and storage conditions N Nath, R Hurst, B Hook, P Meisenheimer, KQ Zhao, N Nassif, RF Bulleit, ... Journal of proteome research 7 (10), 4475-4482, 2008 | 46 | 2008 |
[7] Nucleoprotein photo-cross-linking using halopyrimidine-substituted RNAs KM Meisenheimer, PL Meisenheimer, TH Koch Academic Press 318, 88-104, 2000 | 41 | 2000 |
Proluciferin acetals as bioluminogenic substrates for cytochrome P450 activity and probes for CYP3A inhibition PL Meisenheimer, HT Uyeda, D Ma, M Sobol, MG McDougall, C Corona, ... Drug Metabolism and Disposition 39 (12), 2403-2410, 2011 | 40 | 2011 |
Direct phosphorylation of psilocin enables optimized cGMP kilogram-scale manufacture of psilocybin RB Kargbo, A Sherwood, A Walker, NV Cozzi, RE Dagger, J Sable, ... ACS omega 5 (27), 16959-16966, 2020 | 38 | 2020 |
Bioluminescent assays for ADME evaluation: dialing in CYP selectivity with luminogenic substrates JJ Cali, D Ma, MG Wood, PL Meisenheimer, DH Klaubert Expert Opinion on Drug Metabolism & Toxicology 8 (9), 1115-1130, 2012 | 38 | 2012 |
Coelenterazine derivatives and methods of using same DH Klaubert, P Meisenheimer, J Unch, W Zhou US Patent 9,487,520, 2016 | 31 | 2016 |
Bioluminescent cell-based NAD (P)/NAD (P) H assays for rapid dinucleotide measurement and inhibitor screening J Vidugiriene, D Leippe, M Sobol, G Vidugiris, W Zhou, P Meisenheimer, ... Assay and drug development technologies 12 (9-10), 514-526, 2014 | 30 | 2014 |