| Structural basis of ultraviolet-B perception by UVR8 D Wu, Q Hu, Z Yan, W Chen, C Yan, X Huang, J Zhang, P Yang, H Deng, ... Nature 484 (7393), 214-219, 2012 | 492 | 2012 |
| Atomic structure of the apoptosome: mechanism of cytochrome c-and dATP-mediated activation of Apaf-1 M Zhou, Y Li, Q Hu, X Bai, W Huang, C Yan, SHW Scheres, Y Shi Genes & development 29 (22), 2349-2361, 2015 | 252 | 2015 |
| Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4 S Qi, Y Pang, Q Hu, Q Liu, H Li, Y Zhou, T He, Q Liang, Y Liu, X Yuan, ... Cell 141 (3), 446-457, 2010 | 186 | 2010 |
| Structure and mechanism of the hexameric MecA–ClpC molecular machine F Wang, Z Mei, Y Qi, C Yan, Q Hu, J Wang, Y Shi Nature 471 (7338), 331-335, 2011 | 156 | 2011 |
| Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme Y Li, M Zhou, Q Hu, X Bai, W Huang, SHW Scheres, Y Shi Proceedings of the National Academy of Sciences 114 (7), 1542-1547, 2017 | 128 | 2017 |
| Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome Q Hu, D Wu, W Chen, Z Yan, C Yan, T He, Q Liang, Y Shi Proceedings of the National Academy of Sciences 111 (46), 16254-16261, 2014 | 128 | 2014 |
| GTP-State-Selective Cyclic Peptide Ligands of K-Ras (G12D) Block Its Interaction with Raf Z Zhang, R Gao, Q Hu, H Peacock, DM Peacock, S Dai, KM Shokat, ... ACS Central Science 6 (10), 1753–1761, 2020 | 95 | 2020 |
| Proteolytic processing of the caspase-9 zymogen is required for apoptosome-mediated activation of caspase-9 Q Hu, D Wu, W Chen, Z Yan, Y Shi Journal of Biological Chemistry 288 (21), 15142-15147, 2013 | 75 | 2013 |
| Crystal structure of a bacterial homologue of SWEET transporters J Wang, C Yan, Y Li, K Hirata, M Yamamoto, N Yan, Q Hu Cell research 24 (12), 1486-1489, 2014 | 66 | 2014 |
| Disease-Causing Mutations in the G Protein Gαs Subvert the Roles of GDP and GTP Q Hu, KM Shokat Cell 173 (5), 1254-1264. e11, 2018 | 65 | 2018 |
| Mechanistic insights into CED-4-mediated activation of CED-3 W Huang, T Jiang, W Choi, S Qi, Y Pang, Q Hu, Y Xu, X Gong, PD Jeffrey, ... Genes & development 27 (18), 2039-2048, 2013 | 48 | 2013 |
| Development of Highly Potent Noncovalent Inhibitors of SARS-CoV-2 3CLpro N Hou, L Shuai, L Zhang, X Xie, K Tang, Y Zhu, Y Yu, W Zhang, Q Tan, ... ACS central science 9 (2), 217-227, 2023 | 46 | 2023 |
| State-selective modulation of heterotrimeric Gαs signaling with macrocyclic peptides SA Dai, Q Hu, R Gao, EE Blythe, KK Touhara, H Peacock, Z Zhang, ... Cell 185 (21), 3950-3965.e25, 2022 | 38 | 2022 |
| Molecular determinants of MecA as a degradation tag for the ClpCP protease Z Mei, F Wang, Y Qi, Z Zhou, Q Hu, H Li, J Wu, Y Shi Journal of Biological Chemistry 284 (49), 34366-34375, 2009 | 30 | 2009 |
| Chemical genetic inhibition of DEAD-box proteins using covalent complementarity KJ Barkovich, MK Moore, Q Hu, KM Shokat Nucleic acids research 46 (17), 8689-8699, 2018 | 13 | 2018 |
| Crystal structure of the MecA degradation tag F Wang, Z Mei, Y Qi, C Yan, S Xiang, Z Zhou, Q Hu, J Wang, Y Shi Journal of Biological Chemistry 284 (49), 34376-34381, 2009 | 13 | 2009 |
| Regulation of RAS palmitoyltransferases by accessory proteins and palmitoylation A Yang, S Liu, Y Zhang, J Chen, Y Fan, F Wang, Y Zou, S Feng, J Wu, ... Nature Structural & Molecular Biology, 1-11, 2024 | 8 | 2024 |
| BRET-based self-cleaving biosensors for SARS-CoV-2 3CLpro inhibitor discovery N Hou, C Peng, L Zhang, Y Zhu, Q Hu Microbiology Spectrum 10 (4), e02559-21, 2022 | 5 | 2022 |
| Resistance mechanisms of SARS-CoV-2 3CLpro to the non-covalent inhibitor WU-04 L Zhang, X Xie, H Luo, R Qian, Y Yang, H Yu, J Huang, PY Shi, Q Hu Cell Discovery 10 (1), 40, 2024 | 3 | 2024 |
| Novel X-linked inhibitor of apoptosis protein inhibitors as probes of apoptosis in biology and medicine Q Hu, A Nie, K Welsh, FRP Crisóstomo, X Zhu, Z Li, J An, JC Reed, ... Experimental Biology and Medicine 236 (2), 247-251, 2011 | 2 | 2011 |
