Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling Y Yu, SO Yoon, G Poulogiannis, Q Yang, XM Ma, J Villén, N Kubica, ... Science 332 (6035), 1322-1326, 2011 | 975 | 2011 |
Landscape of intercellular crosstalk in healthy and NASH liver revealed by single-cell secretome gene analysis X Xiong, H Kuang, S Ansari, T Liu, J Gong, S Wang, XY Zhao, Y Ji, C Li, ... Molecular cell 75 (3), 644-660. e5, 2019 | 576 | 2019 |
Site-specific characterization of the Asp-and Glu-ADP-ribosylated proteome Y Zhang, J Wang, M Ding, Y Yu Nature methods 10 (10), 981-984, 2013 | 359 | 2013 |
Chemical genetic discovery of PARP targets reveals a role for PARP-1 in transcription elongation BA Gibson, Y Zhang, H Jiang, KM Hussey, JH Shrimp, H Lin, F Schwede, ... Science 353 (6294), 45-50, 2016 | 336 | 2016 |
The LC domain of hnRNPA2 adopts similar conformations in hydrogel polymers, liquid-like droplets, and nuclei S Xiang, M Kato, LC Wu, Y Lin, M Ding, Y Zhang, Y Yu, SL McKnight Cell 163 (4), 829-839, 2015 | 297 | 2015 |
Sin1 phosphorylation impairs mTORC2 complex integrity and inhibits downstream Akt signalling to suppress tumorigenesis P Liu, W Gan, H Inuzuka, AS Lazorchak, D Gao, O Arojo, D Liu, L Wan, ... Nature cell biology 15 (11), 1340-1350, 2013 | 296 | 2013 |
Highly ordered large caged cubic mesoporous silica structures templated by triblock PEO–PBO–PEO copolymer C Yu, Y Yu, D Zhao Chemical Communications, 575-576, 2000 | 286 | 2000 |
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA H Ji, CS Fraser, Y Yu, J Leary, JA Doudna Proceedings of the National Academy of Sciences 101 (49), 16990-16995, 2004 | 254 | 2004 |
Toxic PRn poly-dipeptides encoded by the C9orf72 repeat expansion block nuclear import and export KY Shi, E Mori, ZF Nizami, Y Lin, M Kato, S Xiang, LC Wu, M Ding, Y Yu, ... Proceedings of the National Academy of Sciences 114 (7), E1111-E1117, 2017 | 243 | 2017 |
Quantitative phosphoproteomic analysis of the molecular substrates of sleep need Z Wang, J Ma, C Miyoshi, Y Li, M Sato, Y Ogawa, T Lou, C Ma, X Gao, ... Nature 558 (7710), 435-439, 2018 | 212 | 2018 |
Post-transcriptional regulation of de novo lipogenesis by mTORC1-S6K1-SRPK2 signaling G Lee, Y Zheng, S Cho, C Jang, C England, JM Dempsey, Y Yu, X Liu, ... Cell 171 (7), 1545-1558. e18, 2017 | 199 | 2017 |
Glycogen synthase kinase (GSK)-3 promotes p70 ribosomal protein S6 kinase (p70S6K) activity and cell proliferation S Shin, L Wolgamott, Y Yu, J Blenis, SO Yoon Proceedings of the National Academy of Sciences 108 (47), E1204-E1213, 2011 | 194 | 2011 |
The emerging function and mechanism of ceRNAs in cancer Y Wang, J Hou, D He, M Sun, P Zhang, Y Yu, Y Chen Trends in Genetics 32 (4), 211-224, 2016 | 166 | 2016 |
Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells T Yi, B Zhai, Y Yu, Y Kiyotsugu, T Raschle, M Etzkorn, HC Seo, M Nagiec, ... Proceedings of the National Academy of Sciences 111 (21), E2182-E2190, 2014 | 147 | 2014 |
Heterodimerization of CCR2 chemokines and regulation by glycosaminoglycan binding SE Crown, Y Yu, MD Sweeney, JA Leary, TM Handel Journal of Biological Chemistry 281 (35), 25438-25446, 2006 | 143 | 2006 |
mTORC1 promotes metabolic reprogramming by the suppression of GSK3-dependent Foxk1 phosphorylation L He, AP Gomes, X Wang, SO Yoon, G Lee, MJ Nagiec, S Cho, A Chavez, ... Molecular cell 70 (5), 949-960. e4, 2018 | 131 | 2018 |
Poly-ADP ribosylation of PTEN by tankyrases promotes PTEN degradation and tumor growth N Li, Y Zhang, X Han, K Liang, J Wang, L Feng, W Wang, Z Songyang, ... Genes & development 29 (2), 157-170, 2015 | 131 | 2015 |
Grb10 promotes lipolysis and thermogenesis by phosphorylation-dependent feedback inhibition of mTORC1 M Liu, J Bai, S He, R Villarreal, D Hu, C Zhang, X Yang, H Liang, TJ Slaga, ... Cell metabolism 19 (6), 967-980, 2014 | 124 | 2014 |
Sensitive multiplexed analysis of kinase activities and activity-based kinase identification K Kubota, R Anjum, Y Yu, RC Kunz, JN Andersen, M Kraus, H Keilhack, ... Nature biotechnology 27 (10), 933-940, 2009 | 122 | 2009 |
Mass spectrometric analysis of the human 40S ribosomal subunit: native and HCV IRES‐bound complexes Y Yu, H Ji, JA Doudna, JA Leary Protein science 14 (6), 1438-1446, 2005 | 122 | 2005 |