Intestinal enteroendocrine lineage cells possess homeostatic and injury-inducible stem cell activity KS Yan, O Gevaert, GXY Zheng, B Anchang, CS Probert, KA Larkin, ... Cell stem cell 21 (1), 78-90. e6, 2017 | 353 | 2017 |
DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer SM Sureban, R May, D Qu, N Weygant, P Chandrakesan, N Ali, ... PloS one 8 (9), e73940, 2013 | 155 | 2013 |
Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1 N Weygant, D Qu, WL Berry, R May, P Chandrakesan, DB Owen, ... Molecular cancer 13, 1-14, 2014 | 127 | 2014 |
XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism SM Sureban, R May, N Weygant, D Qu, P Chandrakesan, ... Cancer letters 351 (1), 151-161, 2014 | 125 | 2014 |
Dclk1, a tumor stem cell marker, regulates pro-survival signaling and self-renewal of intestinal tumor cells P Chandrakesan, J Yao, D Qu, R May, N Weygant, Y Ge, N Ali, ... Molecular Cancer 16, 1-14, 2017 | 108 | 2017 |
DCLK1 is a broadly dysregulated target against epithelial-mesenchymal transition, focal adhesion, and stemness in clear cell renal carcinoma N Weygant, D Qu, R May, RM Tierney, WL Berry, L Zhao, S Agarwal, ... Oncotarget 6 (4), 2193, 2015 | 96 | 2015 |
Brief report: Dclk1 deletion in tuft cells results in impaired epithelial repair after radiation injury R May, D Qu, N Weygant, P Chandrakesan, N Ali, SA Lightfoot, L Li, ... Stem cells 32 (3), 822-827, 2014 | 89 | 2014 |
DCLK1 facilitates intestinal tumor growth via enhancing pluripotency and epithelial mesenchymal transition. P Chandrakesan, N Weygant, R May, D Qu, HR Chinthalapally, ... Oncotarget 5 (19), 9269-9280, 2014 | 84 | 2014 |
Utility of a bacterial infection model to study epithelial–mesenchymal transition, mesenchymal–epithelial transition or tumorigenesis P Chandrakesan, B Roy, L Jakkula, I Ahmed, P Ramamoorthy, O Tawfik, ... Oncogene 33 (20), 2639-2654, 2014 | 78 | 2014 |
Chemopreventive effect of bacoside A on N-nitrosodiethylamine-induced hepatocarcinogenesis in rats P Janani, K Sivakumari, A Geetha, B Ravisankar, C Parthasarathy Journal of cancer research and clinical oncology 136, 759-770, 2010 | 74 | 2010 |
Ablation of doublecortin-like kinase 1 in the colonic epithelium exacerbates dextran sulfate sodium-induced colitis D Qu, N Weygant, R May, P Chandrakesan, M Madhoun, N Ali, ... PLoS One 10 (8), e0134212, 2015 | 72 | 2015 |
Critical roles of Notch and Wnt/β-catenin pathways in the regulation of hyperplasia and/or colitis in response to bacterial infection I Ahmed, P Chandrakesan, O Tawfik, L Xia, S Anant, S Umar Infection and immunity 80 (9), 3107-3121, 2012 | 64 | 2012 |
Hepatoprotective activity of bacoside A against N-nitrosodiethylamine-induced liver toxicity in adult rats P Janani, K Sivakumari, C Parthasarathy Cell biology and toxicology 25, 425-434, 2009 | 63 | 2009 |
Diethylhexyl phthalate impairs insulin binding and glucose oxidation in Chang liver cells S Rengarajan, C Parthasarathy, M Anitha, K Balasubramanian Toxicology in vitro 21 (1), 99-102, 2007 | 61 | 2007 |
Plasma DCLK1 is a marker of hepatocellular carcinoma (HCC): Targeting DCLK1 prevents HCC tumor xenograft growth via a microRNA-dependent mechanism SM Sureban, MF Madhoun, R May, D Qu, N Ali, J Fazili, N Weygant, ... Oncotarget 6 (35), 37200, 2015 | 60 | 2015 |
Alternative splice variants of DCLK1 mark cancer stem cells, promote self‐renewal and drug‐resistance, and can be targeted to inhibit tumorigenesis in kidney cancer Y Ge, N Weygant, D Qu, R May, WL Berry, J Yao, P Chandrakesan, ... International journal of cancer 143 (5), 1162-1175, 2018 | 58 | 2018 |
Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells D Qu, J Johnson, P Chandrakesan, N Weygant, R May, N Aiello, A Rhim, ... PloS one 10 (2), e0118933, 2015 | 57 | 2015 |
Novel changes in NF-κB activity during progression and regression phases of hyperplasia: role of MEK, ERK, and p38 P Chandrakesan, I Ahmed, T Anwar, Y Wang, S Sarkar, P Singh, S Peleg, ... Journal of Biological Chemistry 285 (43), 33485-33498, 2010 | 57 | 2010 |
Regulatory roles of Dclk1 in epithelial mesenchymal transition and cancer stem cells P Chandrakesan, J Panneerselvam, D Qu, N Weygant, R May, MS Bronze, ... Journal of carcinogenesis & mutagenesis 7 (2), 2016 | 53 | 2016 |
Dclk1+ small intestinal epithelial tuft cells display the hallmarks of quiescence and self-renewal P Chandrakesan, R May, D Qu, N Weygant, VE Taylor, JD Li, N Ali, ... Oncotarget 6 (31), 30876, 2015 | 49 | 2015 |