The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors E Lefrançais, G Ortiz-Muñoz, A Caudrillier, B Mallavia, F Liu, DM Sayah, ... Nature 544 (7648), 105-109, 2017 | 1172 | 2017 |
IL-33 is processed into mature bioactive forms by neutrophil elastase and cathepsin G E Lefrançais, S Roga, V Gautier, A Gonzalez-de-Peredo, B Monsarrat, ... Proceedings of the National Academy of Sciences 109 (5), 1673-1678, 2012 | 696 | 2012 |
Endogenous IL-33 is highly expressed in mouse epithelial barrier tissues, lymphoid organs, brain, embryos, and inflamed tissues: in situ analysis using a novel Il-33–LacZ gene … M Pichery, E Mirey, P Mercier, E Lefrancais, A Dujardin, N Ortega, ... The Journal of Immunology 188 (7), 3488-3495, 2012 | 546 | 2012 |
Central domain of IL-33 is cleaved by mast cell proteases for potent activation of group-2 innate lymphoid cells E Lefrançais, A Duval, E Mirey, S Roga, E Espinosa, C Cayrol, JP Girard Proceedings of the National Academy of Sciences 111 (43), 15502-15507, 2014 | 415 | 2014 |
Maladaptive role of neutrophil extracellular traps in pathogen-induced lung injury E Lefrançais, B Mallavia, H Zhuo, CS Calfee, MR Looney JCI insight 3 (3), 2018 | 408 | 2018 |
Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice MAK Sedhom, M Pichery, JR Murdoch, B Foligné, N Ortega, S Normand, ... Gut 62 (12), 1714-1723, 2013 | 235 | 2013 |
Extracellular DNA, neutrophil extracellular traps, and inflammasome activation in severe asthma ME Lachowicz-Scroggins, EM Dunican, AR Charbit, W Raymond, ... American journal of respiratory and critical care medicine 199 (9), 1076-1085, 2019 | 215 | 2019 |
2012 ECS-ECN JUNIOR REVIEW AWARD–Mechanisms of IL-33 processing and secretion: differences and similarities between IL-1 family members E Lefrançais, C Cayrol European cytokine network 23 (4), 120-127, 2012 | 147 | 2012 |
Mitochondrial DNA stimulates TLR9-dependent neutrophil extracellular trap formation in primary graft dysfunction B Mallavia, F Liu, E Lefrançais, SJ Cleary, N Kwaan, JJ Tian, M Magnen, ... American journal of respiratory cell and molecular biology 62 (3), 364-372, 2020 | 90 | 2020 |
Platelet biogenesis in the lung circulation E Lefrançais, MR Looney Physiology 34 (6), 392-401, 2019 | 80 | 2019 |
Aspirin reduces lipopolysaccharide-induced pulmonary inflammation in human models of ARDS U Hamid, A Krasnodembskaya, M Fitzgerald, M Shyamsundar, ... Thorax 72 (11), 971-980, 2017 | 74 | 2017 |
LPS-induced lung platelet recruitment occurs independently from neutrophils, PSGL-1, and P-selectin SJ Cleary, C Hobbs, RT Amison, S Arnold, BG O’Shaughnessy, ... American journal of respiratory cell and molecular biology 61 (2), 232-243, 2019 | 55 | 2019 |
Cystic fibrosis transmembrane conductance regulator dysfunction in platelets drives lung hyperinflammation G Ortiz-Muñoz, AY Michelle, E Lefrançais, B Mallavia, C Valet, JJ Tian, ... The Journal of clinical investigation 130 (4), 2041-2053, 2020 | 45 | 2020 |
Caspase-1-driven neutrophil pyroptosis and its role in host susceptibility to Pseudomonas aeruginosa K Santoni, D Pericat, L Gorse, J Buyck, M Pinilla, L Prouvensier, ... PLoS pathogens 18 (7), e1010305, 2022 | 31 | 2022 |
ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection D Corral, A Charton, MZ Krauss, E Blanquart, F Levillain, E Lefrancais, ... Cell Reports 39 (3), 2022 | 25 | 2022 |
Neutralizing extracellular histones in acute respiratory distress syndrome. A new role for an endogenous pathway E Lefrançais, MR Looney American Journal of Respiratory and Critical Care Medicine 196 (2), 122-124, 2017 | 21 | 2017 |
Occurrence and role of lung megakaryocytes in infection and inflammation L Gelon, L Fromont, E Lefrançais Frontiers in Immunology 13, 1029223, 2022 | 12 | 2022 |
Method for increasing granulocyte number in a patient by administering superactive IL-33 fragments JP Girard, C Cayrol-Girard, E Lefrancais US Patent 9,611,307, 2017 | 10 | 2017 |
Metabolic control of type 2 innate lymphoid cells plasticity toward protective type 1-like cells during Mycobacterium tuberculosis infection D Corral, A Charton, MZ Krauss, E Blanquart, F Levillain, E Lefrançais, ... bioRxiv, 2021.01. 19.427257, 2021 | 5 | 2021 |
Metabolic regulation of ILC2 differentiation into ILC1-like cells during Mycobacterium tuberculosis infection D Corral, A Charton, MZ Krauss, E Blanquart, F Levillain, E Lefrançais, ... | 3 | 2021 |