| Whole-exome sequencing combined with functional genomics reveals novel candidate driver cancer genes in endometrial cancer H Liang, LWT Cheung, J Li, Z Ju, S Yu, K Stemke-Hale, T Dogruluk, Y Lu, ... Genome research 22 (11), 2120-2129, 2012 | 305 | 2012 |
| Systematic functional annotation of somatic mutations in cancer PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ... Cancer cell 33 (3), 450-462. e10, 2018 | 252 | 2018 |
| Identification of variant-specific functions of PIK3CA by rapid phenotyping of rare mutations T Dogruluk, YH Tsang, M Espitia, F Chen, T Chen, Z Chong, V Appadurai, ... Cancer research 75 (24), 5341-5354, 2015 | 156 | 2015 |
| Moesin is a glioma progression marker that induces proliferation and Wnt/β-catenin pathway activation via interaction with CD44 X Zhu, FC Morales, NK Agarwal, T Dogruluk, M Gagea, MM Georgescu Cancer research 73 (3), 1142-1155, 2013 | 87 | 2013 |
| HOXA1 drives melanoma tumor growth and metastasis and elicits an invasion gene expression signature that prognosticates clinical outcome J Wardwell-Ozgo, T Dogruluk, A Gifford, Y Zhang, TP Heffernan, ... Oncogene 33 (8), 1017-1026, 2014 | 67 | 2014 |
| Characterization of cancer stem-like cells in chordoma E Aydemir, OF Bayrak, F Sahin, B Atalay, GT Kose, M Ozen, S Sevli, ... Journal of neurosurgery 116 (4), 810-820, 2012 | 67 | 2012 |
| Functional annotation of rare gene aberration drivers of pancreatic cancer YH Tsang, T Dogruluk, PM Tedeschi, J Wardwell-Ozgo, H Lu, M Espitia, ... Nature communications 7 (1), 10500, 2016 | 64 | 2016 |
| Coordinate phosphorylation of multiple residues on single AKT1 and AKT2 molecules H Guo, M Gao, Y Lu, J Liang, PL Lorenzi, S Bai, DH Hawke, J Li, ... Oncogene 33 (26), 3463-3472, 2014 | 48 | 2014 |
| Engineering and functional characterization of fusion genes identifies novel oncogenic drivers of cancer H Lu, N Villafane, T Dogruluk, CL Grzeskowiak, K Kong, YH Tsang, ... Cancer research 77 (13), 3502-3512, 2017 | 42 | 2017 |
| Differential expression of MAGEA6 toggles autophagy to promote pancreatic cancer progression YH Tsang, Y Wang, K Kong, C Grzeskowiak, O Zagorodna, T Dogruluk, ... Elife 9, e48963, 2020 | 20 | 2020 |
| A functional genomic approach to actionable gene fusions for precision oncology J Li, H Lu, PKS Ng, A Pantazi, CKM Ip, KJ Jeong, B Amador, R Tran, ... Science Advances 8 (6), eabm2382, 2022 | 16 | 2022 |
