Prioritizing chemicals of ecological concern in Great Lakes tributaries using high-throughput screening data and adverse outcome pathways SR Corsi, LA De Cicco, DL Villeneuve, BR Blackwell, KA Fay, GT Ankley, ... Science of the Total Environment 686, 995-1009, 2019 | 80 | 2019 |
Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout: Results of an International Ring Trial J Nichols, K Fay, MJ Bernhard, I Bischof, J Davis, M Halder, J Hu, ... Toxicological Sciences 164 (2), 563-575, 2018 | 49 | 2018 |
Differentiating pathway-specific from nonspecific effects in high-throughput toxicity data: A foundation for prioritizing adverse outcome pathway development KA Fay, DL Villeneuve, J Swintek, SW Edwards, MD Nelms, BR Blackwell, ... Toxicological Sciences 163 (2), 500-515, 2018 | 49 | 2018 |
Practical approaches to adverse outcome pathway development and weight‐of‐evidence evaluation as illustrated by ecotoxicological case studies KA Fay, DL Villeneuve, CA LaLone, Y Song, KE Tollefsen, GT Ankley Environmental Toxicology and Chemistry 36 (6), 1429-1449, 2017 | 48 | 2017 |
Intra-and interlaboratory reliability of a cryopreserved trout hepatocyte assay for the prediction of chemical bioaccumulation potential KA Fay, RT Mingoia, I Goeritz, DL Nabb, AD Hoffman, BD Ferrell, ... Environmental science & technology 48 (14), 8170-8178, 2014 | 39 | 2014 |
The Eco‐Exposome concept: Supporting an integrated assessment of mixtures of environmental chemicals S Scholz, JW Nichols, BI Escher, GT Ankley, R Altenburger, B Blackwell, ... Environmental toxicology and chemistry 41 (1), 30-45, 2022 | 35 | 2022 |
Comparison of trout hepatocytes and liver S9 fractions as in vitro models for predicting hepatic clearance in fish KA Fay, PN Fitzsimmons, AD Hoffman, JW Nichols Environmental toxicology and chemistry 36 (2), 463-471, 2017 | 31 | 2017 |
Which molecular features affect the intrinsic hepatic clearance rate of ionizable organic chemicals in fish? Y Chen, JLM Hermens, MTO Jonker, JA Arnot, JM Armitage, T Brown, ... Environmental Science & Technology 50 (23), 12722-12731, 2016 | 27 | 2016 |
Impaired swim bladder inflation in early life stage fathead minnows exposed to a deiodinase inhibitor, iopanoic acid JE Cavallin, GT Ankley, BR Blackwell, CA Blanksma, KA Fay, KM Jensen, ... Environmental toxicology and chemistry 36 (11), 2942-2952, 2017 | 25 | 2017 |
Optimizing the use of rainbow trout hepatocytes for bioaccumulation assessments with fish KA Fay, PN Fitzsimmons, AD Hoffman, JW Nichols Xenobiotica 44 (4), 345-351, 2014 | 23 | 2014 |
Pathway‐based approaches for assessing biological hazards of complex mixtures of contaminants: A case study in the Maumee River GT Ankley, JP Berninger, BR Blackwell, JE Cavallin, TW Collette, ... Environmental Toxicology and Chemistry 40 (4), 1098-1122, 2021 | 19 | 2021 |
Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes JA Doering, DL Villeneuve, KA Fay, EC Randolph, KM Jensen, MD Kahl, ... Toxicological Sciences 170 (2), 394-403, 2019 | 17 | 2019 |
Evaluation and comparison of in vitro intrinsic clearance rates measured using cryopreserved hepatocytes from humans, rats, and rainbow trout SR Black, JW Nichols, KA Fay, SR Matten, SG Lynn Toxicology 457, 152819, 2021 | 16 | 2021 |
Allometric scaling of hepatic biotransformation in rainbow trout PN Fitzsimmons, AD Hoffman, KA Fay, JW Nichols Comparative Biochemistry and Physiology Part C: Toxicology & Pharmacology …, 2018 | 14 | 2018 |
Determination of Metabolic Stability Using Cryopreserved Hepatocytes from Rainbow Trout (Oncorhynchus mykiss) KA Fay, DL Nabb, RT Mingoia, I Bischof, JW Nichols, H Segner, ... Current protocols in toxicology 65 (1), 4.42. 1-4.42. 29, 2015 | 14 | 2015 |
Current ecotoxicity testing needs among selected US federal agencies P Ceger, NGR Vinas, D Allen, E Arnold, R Bloom, JC Brennan, C Clarke, ... Regulatory Toxicology and Pharmacology 133, 105195, 2022 | 7 | 2022 |
Expanding non‐invasive approaches for fish‐health monitoring: A survey of the epidermal mucous metabolomes of phylogenetically diverse freshwater fish species DR Ekman, MG Evich, JD Mosley, JA Doering, KA Fay, GT Ankley, ... Journal of Fish Biology 103 (5), 1178-1189, 2023 | 1 | 2023 |
The EnviroTox Platform: Update & Applications MR Embry, AC Bejarano, K Connors, KA Fay, C Mitchell, RR Otter SETAC North America 44th Annual Meeting, 2023 | | 2023 |
In silico NAMs: Recent developments and regulatory applications MR Embry, KA Fay, P Thomas, G Hodges SETAC North America 43rd Annual Meeting, 2022 | | 2022 |
Reliability of In Vitro Methods Used to Measure Intrinsic Clearance of Hydrophobic Organic Chemicals by Rainbow Trout J Nichols, K Fay, MJ Bernhard, I Bischof, J Davis, M Halder, J Hu, ... | | 2018 |