Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy KS Putt, GW Chen, JM Pearson, JS Sandhorst, MS Hoagland, JT Kwon, ... Nature chemical biology 2 (10), 543-550, 2006 | 418 | 2006 |
An enzymatic assay for poly (ADP-ribose) polymerase-1 (PARP-1) via the chemical quantitation of NAD+: application to the high-throughput screening of small molecules as … KS Putt, PJ Hergenrother Analytical biochemistry 326 (1), 78-86, 2004 | 164 | 2004 |
Synthesis and identification of small molecules that potently induce apoptosis in melanoma cells through G1 cell cycle arrest RS Dothager, KS Putt, BJ Allen, BJ Leslie, V Nesterenko, PJ Hergenrother Journal of the American Chemical Society 127 (24), 8686-8696, 2005 | 130 | 2005 |
Identification from a combinatorial library of a small molecule that selectively induces apoptosis in cancer cells V Nesterenko, KS Putt, PJ Hergenrother Journal of the American Chemical Society 125 (48), 14672-14673, 2003 | 105 | 2003 |
Regulation of CAR T cell-mediated cytokine release syndrome-like toxicity using low molecular weight adapters YG Lee, H Chu, Y Lu, CP Leamon, M Srinivasarao, KS Putt, PS Low Nature communications 10 (1), 2681, 2019 | 96 | 2019 |
A small molecule that induces intrinsic pathway apoptosis with unparalleled speed R Palchaudhuri, MJ Lambrecht, RC Botham, KC Partlow, TJ Van Ham, ... Cell reports 13 (9), 2027-2036, 2015 | 87 | 2015 |
Assessment of folate receptor alpha and beta expression in selection of lung and pancreatic cancer patients for receptor targeted therapies J Shen, Y Hu, KS Putt, S Singhal, H Han, DW Visscher, LM Murphy, ... Oncotarget 9 (4), 4485, 2018 | 78 | 2018 |
Assessment of folate receptor-β expression in human neoplastic tissues J Shen, KS Putt, DW Visscher, L Murphy, C Cohen, S Singhal, ... Oncotarget 6 (16), 14700, 2015 | 77 | 2015 |
A new small molecule inhibitor of estrogen receptor α binding to estrogen response elements blocks estrogen-dependent growth of cancer cells C Mao, NM Patterson, MT Cherian, IO Aninye, C Zhang, JB Montoya, ... Journal of Biological Chemistry 283 (19), 12819-12830, 2008 | 73 | 2008 |
Selective liposome targeting of folate receptor positive immune cells in inflammatory diseases S Poh, V Chelvam, W Ayala-López, KS Putt, PS Low Nanomedicine: Nanotechnology, Biology and Medicine 14 (3), 1033-1043, 2018 | 53 | 2018 |
Folate-targeted dendrimers selectively accumulate at sites of inflammation in mouse models of ulcerative colitis and atherosclerosis S Poh, KS Putt, PS Low Biomacromolecules 18 (10), 3082-3088, 2017 | 51 | 2017 |
Evaluation of a carbonic anhydrase IX-targeted near-infrared dye for fluorescence-guided surgery of hypoxic tumors PC Lv, J Roy, KS Putt, PS Low Molecular pharmaceutics 13 (5), 1618-1625, 2016 | 50 | 2016 |
Direct quantitation of poly (ADP-ribose) polymerase (PARP) activity as a means to distinguish necrotic and apoptotic death in cell and tissue samples KS Putt, GJ Beilman, PJ Hergenrother Chembiochem 6 (1), 53-54, 2005 | 46 | 2005 |
Ophthalmic lens system capable of wireless communication with multiple external devices RB Pugh, A Toner, KS Putt, CA Higham, S Snook US Patent 9,225,375, 2015 | 45 | 2015 |
A nonradiometric, high-throughput assay for poly (ADP-ribose) glycohydrolase (PARG): application to inhibitor identification and evaluation KS Putt, PJ Hergenrother Analytical biochemistry 333 (2), 256-264, 2004 | 45 | 2004 |
Assessment of cholecystokinin 2 receptor (CCK2R) in neoplastic tissue J Roy, KS Putt, D Coppola, ME Leon, FK Khalil, BA Centeno, N Clark, ... Oncotarget 7 (12), 14605, 2016 | 41 | 2016 |
Folate-conjugated liposomes target and deliver therapeutics to immune cells in a rat model of rheumatoid arthritis S Poh, V Chelvam, LE Kelderhouse, W Ayala-López, B Vaitilingam, ... Nanomedicine 12 (20), 2441-2451, 2017 | 35 | 2017 |
Selective tumor targeting of desacetyl vinblastine hydrazide and tubulysin B via conjugation to a cholecystokinin 2 receptor (CCK2R) ligand C Wayua, J Roy, KS Putt, PS Low Molecular pharmaceutics 12 (7), 2477-2483, 2015 | 34 | 2015 |
Depletion of activated macrophages with a folate receptor-beta-specific antibody improves symptoms in mouse models of rheumatoid arthritis Y Hu, B Wang, J Shen, SA Low, KS Putt, HWM Niessen, EL Matteson, ... Arthritis research & therapy 21, 1-14, 2019 | 33 | 2019 |
The compound 13‐D selectively induces apoptosis in white blood cancers versus other cancer cell types KS Putt, V Nesterenko, RS Dothager, PJ Hergenrother ChemBioChem 7 (12), 1916-1922, 2006 | 33 | 2006 |