Improved biocatalysts by directed evolution and rational protein design UT Bornscheuer, M Pohl Current opinion in chemical biology 5 (2), 137-143, 2001 | 686 | 2001 |
Stabilization of NAD‐dependent formate dehydrogenase from Candida boidinii by site‐directed mutagenesis of cysteine residues H Slusarczyk, S Felber, MR Kula, M Pohl European journal of biochemistry 267 (5), 1280-1289, 2000 | 274 | 2000 |
Development of a donor− acceptor concept for enzymatic cross-coupling reactions of aldehydes: the first asymmetric cross-benzoin condensation P Dünkelmann, D Kolter-Jung, A Nitsche, AS Demir, P Siegert, B Lingen, ... Journal of the American Chemical Society 124 (41), 12084-12085, 2002 | 266 | 2002 |
Effect of Oxygen Limitation and Medium Composition on Escherichia coli Fermentation in Shake‐Flask Cultures M Losen, B Frölich, M Pohl, J Büchs Biotechnology progress 20 (4), 1062-1068, 2004 | 235 | 2004 |
A new perspective on thiamine catalysis M Pohl, GA Sprenger, M Müller Current opinion in biotechnology 15 (4), 335-342, 2004 | 223 | 2004 |
Thiamin‐Diphosphate‐Dependent Enzymes: New Aspects of Asymmetric C-C Bond Formation M Pohl, B Lingen, M Müller Chemistry–A European Journal 8 (23), 5288-5295, 2002 | 221 | 2002 |
Enantioselective synthesis of α‐hydroxy ketones via benzaldehyde lyase‐catalyzed C− C bond formation reaction AS Demir, Ö Şeşenoglu, E Eren, B Hosrik, M Pohl, E Janzen, D Kolter, ... Advanced Synthesis & Catalysis 344 (1), 96-103, 2002 | 211 | 2002 |
Benzoylformate decarboxylase from Pseudomonas putida as stable catalyst for the synthesis of chiral 2‐hydroxy ketones H Iding, T Dünnwald, L Greiner, A Liese, M Müller, P Siegert, J Grötzinger, ... Chemistry–A European Journal 6 (8), 1483-1495, 2000 | 208 | 2000 |
Two steps in one pot: enzyme cascade for the synthesis of nor (pseudo) ephedrine from inexpensive starting materials T Sehl, HC Hailes, JM Ward, R Wardenga, E von Lieres, H Offermann, ... Angewandte Chemie International Edition 52 (26), 6772-6775, 2013 | 200 | 2013 |
Thiamin diphosphate in biological chemistry: exploitation of diverse thiamin diphosphate‐dependent enzymes for asymmetric chemoenzymatic synthesis M Müller, D Gocke, M Pohl The FEBS journal 276 (11), 2894-2904, 2009 | 170 | 2009 |
Enantioselective synthesis of hydroxy ketones through cleavage and formation of acyloin linkage. Enzymatic kinetic resolution via C–C bond cleavage AS Demir, M Pohl, E Janzen, M Müller Journal of the Chemical Society, Perkin Transactions 1, 633-635, 2001 | 170 | 2001 |
Characterization of Phenylpyruvate Decarboxylase, Involved in Auxin Production of Azospirillum brasilense S Spaepen, W Versées, D Gocke, M Pohl, J Steyaert, J Vanderleyden Journal of Bacteriology 189 (21), 7626-7633, 2007 | 152 | 2007 |
Synthetic potential of thiamin diphosphate-dependent enzymes GA Sprenger, M Pohl Journal of Molecular Catalysis B: Enzymatic 6 (3), 145-159, 1999 | 148 | 1999 |
Application of α-keto acid decarboxylases in biotransformations H Iding, P Siegert, K Mesch, M Pohl Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1998 | 147 | 1998 |
C-C bond formation using ThDP-dependent lyases M Müller, GA Sprenger, M Pohl Current Opinion in Chemical Biology 17 (2), 261-270, 2013 | 130 | 2013 |
Asymmetric benzoin reaction catalyzed by benzoylformate decarboxylase AS Demir, T Dünnwald, H Iding, M Pohl, M Müller Tetrahedron: Asymmetry 10 (24), 4769-4774, 1999 | 117 | 1999 |
Exchanging the substrate specificities of pyruvate decarboxylase from Zymomonas mobilis and benzoylformate decarboxylase from Pseudomonas putida P Siegert, MJ McLeish, M Baumann, H Iding, MM Kneen, GL Kenyon, ... Protein Engineering Design and Selection 18 (7), 345-357, 2005 | 110 | 2005 |
Efficient 2-step biocatalytic strategies for the synthesis of all nor (pseudo) ephedrine isomers T Sehl, HC Hailes, JM Ward, U Menyes, M Pohl, D Rother Green chemistry 16 (6), 3341-3348, 2014 | 105 | 2014 |
A New (R)-Selective Hydroxynitrile Lyase from Arabidopsis thaliana with an α/β-Hydrolase Fold J Andexer, J von Langermann, A Mell, M Bocola, U Kragl, T Eggert, ... | 104* | 2007 |
Continuous production of (R)‐phenylacetylcarbinol in an enzyme‐membrane reactor using a potent mutant of pyruvate decarboxylase from Zymomonas mobilis G Goetz, P Iwan, B Hauer, M Breuer, M Pohl Biotechnology and bioengineering 74 (4), 317-325, 2001 | 103 | 2001 |