Electrochemical aptamer-based sensors for improved therapeutic drug monitoring and high-precision, feedback-controlled drug delivery P Dauphin-Ducharme, K Yang, N Arroyo-Currás, KL Ploense, Y Zhang, ... ACS sensors 4 (10), 2832-2837, 2019 | 182 | 2019 |
Fibrillation precursor of superoxide dismutase 1 revealed by gradual tuning of the protein-folding equilibrium L Lang, M Kurnik, J Danielsson, M Oliveberg Proceedings of the National Academy of Sciences 109 (44), 17868-17873, 2012 | 81 | 2012 |
Potent α-synuclein aggregation inhibitors, identified by high-throughput screening, mainly target the monomeric state M Kurnik, C Sahin, CB Andersen, N Lorenzen, L Giehm, ... Cell chemical biology 25 (11), 1389-1402. e9, 2018 | 79 | 2018 |
Elucidating the mechanisms underlying the signal drift of electrochemical aptamer-based sensors in whole blood KK Leung, AM Downs, G Ortega, M Kurnik, KW Plaxco ACS sensors 6 (9), 3340-3347, 2021 | 69 | 2021 |
Cutting off functional loops from homodimeric enzyme superoxide dismutase 1 (SOD1) leaves monomeric β-barrels J Danielsson, M Kurnik, L Lang, M Oliveberg Journal of Biological Chemistry 286 (38), 33070-33083, 2011 | 68 | 2011 |
Simulation-based approach to determining electron transfer rates using square-wave voltammetry P Dauphin-Ducharme, N Arroyo-Currás, M Kurnik, G Ortega, H Li, ... Langmuir 33 (18), 4407-4413, 2017 | 67 | 2017 |
Folding without charges M Kurnik, L Hedberg, J Danielsson, M Oliveberg Proceedings of the National Academy of Sciences 109 (15), 5705-5710, 2012 | 62 | 2012 |
New architecture for reagentless, protein-based electrochemical biosensors D Kang, S Sun, M Kurnik, D Morales, FW Dahlquist, KW Plaxco Journal of the American Chemical Society 139 (35), 12113-12116, 2017 | 45 | 2017 |
Open source software for the real-time control, processing, and visualization of high-volume electrochemical data SD Curtis, KL Ploense, M Kurnik, G Ortega, C Parolo, TE Kippin, ... Analytical chemistry 91 (19), 12321-12328, 2019 | 42 | 2019 |
Global structural motions from the strain of a single hydrogen bond J Danielsson, W Awad, K Saraboji, M Kurnik, L Lang, L Leinartaitė, ... Proceedings of the National Academy of Sciences 110 (10), 3829-3834, 2013 | 41 | 2013 |
An electrochemical biosensor architecture based on protein folding supports direct real‐time measurements in whole blood M Kurnik, EZ Pang, KW Plaxco Angewandte Chemie International Edition 59 (42), 18442-18445, 2020 | 33 | 2020 |
An electrochemical scaffold sensor for rapid syphilis diagnosis NE Ogden, M Kurnik, C Parolo, KW Plaxco Analyst 144 (17), 5277-5283, 2019 | 18 | 2019 |
Quantitative measurements of protein− surface interaction thermodynamics M Kurnik, G Ortega, P Dauphin-Ducharme, H Li, A Caceres, KW Plaxco Proceedings of the National Academy of Sciences 115 (33), 8352-8357, 2018 | 16 | 2018 |
Surface attachment enhances the thermodynamic stability of protein L G Ortega, M Kurnik, P Dauphin‐Ducharme, H Li, N Arroyo‐Currás, ... Angewandte Chemie 131 (6), 1728-1732, 2019 | 10 | 2019 |
The highly specific, cell cycle–regulated methyltransferase from Caulobacter crescentus relies on a novel DNA recognition mechanism NO Reich, E Dang, M Kurnik, S Pathuri, CB Woodcock Journal of Biological Chemistry 293 (49), 19038-19046, 2018 | 10 | 2018 |
Direct detection of neuropeptide dynorphin A binding to the second extracellular loop of the κ opioid receptor using a soluble protein scaffold J Björnerås, M Kurnik, M Oliveberg, A Gräslund, L Mäler, J Danielsson The FEBS Journal 281 (3), 814-824, 2014 | 9 | 2014 |
Attachment of proteins to a hydroxyl-terminated surface eliminates the stabilizing effects of polyols G Ortega, M Kurnik, BK Gautam, KW Plaxco Journal of the American Chemical Society 142 (36), 15349-15354, 2020 | 7 | 2020 |
High fidelity DNA strand-separation is the major specificity determinant in DNA methyltransferase CcrM’s catalytic mechanism O Konttinen, J Carmody, M Kurnik, KA Johnson, N Reich Nucleic Acids Research 51 (13), 6883-6898, 2023 | 1 | 2023 |
Investigation of the DNA strand separation step by DNA methyltransferase Caulobacter Crescentus OR Konttinen, NO Reich, J Carmody, M Kurnik The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Understanding the Biophysics of Protein-Surface Interactions G Ortega, M Kurnik, PD Ducharme, H Li, N Arroyo-Curras, B Gautam, ... Biophysical Journal 116 (3), 464a, 2019 | | 2019 |