Development of isatin-thiazolo [3, 2-a] benzimidazole hybrids as novel CDK2 inhibitors with potent in vitro apoptotic anti-proliferative activity: Synthesis, biological and … WM Eldehna, MA El Hassab, MF Abo-Ashour, T Al-Warhi, MM Elaasser, ... Bioorganic Chemistry 110, 104748, 2021 | 63 | 2021 |
Identification of Novel Cyanopyridones and Pyrido[2,3-d]pyrimidines as Anticancer Agents with Dual VEGFR-2/HER-2 Inhibitory Action: Synthesis, Biological … T Al-Warhi, AAM Sallam, LR Hemeda, MA El Hassab, N Aljaeed, ... Pharmaceuticals 15 (10), 1262, 2022 | 62 | 2022 |
GC/MS Profiling, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase and Anti-Hyaluronidase Activities of a Stenocarpus sinuatus Leaves Extract MM Younis, IM Ayoub, NM Mostafa, MA El Hassab, WM Eldehna, ... Plants 11 (7), 918, 2022 | 57 | 2022 |
Multi-step in silico discovery of natural drugs against COVID-19 targeting main protease EB Elkaeed, FS Youssef, IH Eissa, H Elkady, AA Alsfouk, ML Ashour, ... International Journal of Molecular Sciences 23 (13), 6912, 2022 | 45 | 2022 |
In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches MA El Hassab, TM Ibrahim, ST Al-Rashood, A Alharbi, RO Eskandrani, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 727-736, 2021 | 45 | 2021 |
Development of novel isatin–nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing–bacteria ZM Elsayed, WM Eldehna, MM Abdel-Aziz, MA El Hassab, EB Elkaeed, ... Journal of enzyme inhibition and medicinal chemistry 36 (1), 384-392, 2021 | 44 | 2021 |
Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4, 5-dihydropyrazoles as anticancer agents with potential EGFR … WM Eldehna, MA El Hassab, ZM Elsayed, T Al-Warhi, H Elkady, ... Scientific reports 12 (1), 12821, 2022 | 41 | 2022 |
Identification of a New Potential SARS-COV-2 RNA-Dependent RNA Polymerase Inhibitor via Combining Fragment-Based Drug Design, Docking, Molecular … MA El Hassab, AA Shoun, ST Al-Rashood, T Al-Warhi, WM Eldehna Frontiers in Chemistry 8, 584894, 2020 | 41 | 2020 |
Olive leaves as a potential phytotherapy in the treatment of COVID-19 disease; A mini-review SM Abdelgawad, MAE Hassab, MAS Abourehab, EB Elkaeed, ... Frontiers in pharmacology 13, 879118, 2022 | 27 | 2022 |
Toward the identification of potential α-ketoamide covalent inhibitors for SARS-CoV-2 main protease: Fragment-based drug design and MM-PBSA calculations MAE Hassab, M Fares, MKAH Amin, ST Al-Rashood, A Alharbi, ... Processes 9 (6), 1004, 2021 | 24 | 2021 |
Identification of potential inhibitors for HCV NS3 genotype 4a by combining protein–ligand interaction fingerprint, 3D pharmacophore, docking, and dynamic simulation MAEM El-Hasab, EE El-Bastawissy, TF El-Moselhy Journal of Biomolecular Structure and Dynamics 36 (7), 1713-1727, 2018 | 23 | 2018 |
Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia HAS El-Nashar, AM Sayed, HAM El-Sherief, ME Rateb, L Akil, I Khadra, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2199950, 2023 | 20 | 2023 |
Direct acting anti-hepatitis C combinations as potential COVID-19 protease inhibitors M Hamed, M El-Hasab, FR Mansour VirusDisease 32 (2), 279-285, 2021 | 20 | 2021 |
Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n-Hexane Extract and Essential Oil of Guava Leaves SH Aly, OA Eldahshan, ST Al-Rashood, FA Binjubair, MA El Hassab, ... Molecules 27 (24), 8979, 2022 | 19 | 2022 |
Multi-stage structure-based virtual screening approach towards identification of potential SARS-CoV-2 NSP13 helicase inhibitors MA El Hassab, WM Eldehna, ST Al-Rashood, A Alharbi, RO Eskandrani, ... Journal of Enzyme Inhibition and Medicinal Chemistry 37 (1), 563-572, 2022 | 18 | 2022 |
Rumex vesicarius L. boosts the effectiveness of sorafenib in triple-negative breast cancer by downregulating BCl2, mTOR, and JNK, and upregulating p21 expression A Ghanem, MA Ali, MA Elkady, SSA Mageed, MA El Hassab, ... Pathology-Research and Practice 250, 154807, 2023 | 17 | 2023 |
Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer EA Abdelsalam, AA Abd El-Hafeez, WM Eldehna, MA El Hassab, ... Journal of enzyme inhibition and medicinal chemistry 37 (1), 2265-2282, 2022 | 17 | 2022 |
Development of 4-((3-oxo-3-phenylpropyl) amino) benzenesulfonamide derivatives utilizing tail/dual-tail approaches as novel carbonic anhydrase inhibitors MM Elbadawi, WM Eldehna, A Nocentini, WR Somaa, ST Al-Rashood, ... European Journal of Medicinal Chemistry 238, 114412, 2022 | 17 | 2022 |
In silico identification of potential SARS COV-2 2′-O-methyltransferase inhibitor: Fragment-based screening approach and MM-PBSA calculations MA El Hassab, TM Ibrahim, AA Shoun, ST Al-Rashood, HM Alkahtani, ... RSC advances 11 (26), 16026-16033, 2021 | 17 | 2021 |
Fenticonazole nitrate loaded trans-novasomes for effective management of tinea corporis: design characterization, in silico study, and exploratory clinical appraisal R Albash, MH Ragaie, MAE Hassab, R El-Haggar, WM Eldehna, ... Drug Delivery 29 (1), 1100-1111, 2022 | 16 | 2022 |