| Plasmid-based one-pot saturation mutagenesis EE Wrenbeck, JR Klesmith, JA Stapleton, A Adeniran, KEJ Tyo, ... Nature Methods, 2016 | 189 | 2016 |
| Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning JR Klesmith, JP Bacik, EE Wrenbeck, R Michalczyk, TA Whitehead Proceedings of the National Academy of Sciences, 2017 | 155 | 2017 |
| The interrelationship between promoter strength, gene expression, and growth rate MS Bienick, KW Young, JR Klesmith, EE Detwiler, KJ Tomek, ... PloS one 9 (10), e109105, 2014 | 97 | 2014 |
| High-resolution sequence-function mapping of full-length proteins CA Kowalsky, JR Klesmith, JA Stapleton, V Kelly, N Reichkitzer, ... PloS one 10 (3), e0118193, 2015 | 80 | 2015 |
| Comprehensive sequence-flux mapping of a levoglucosan utilization pathway in E. coli JR Klesmith, JP Bacik, R Michalczyk, TA Whitehead ACS Synth. Biol., 2015 | 75 | 2015 |
| Retargeting CD19 Chimeric Antigen Receptor T Cells via Engineered CD19-Fusion Proteins JR Klesmith, L Su, L Wu, IA Schrack, FJ Dufort, A Birt, C Ambrose, ... Mol. Pharmaceutics 16 (8), 3544-3558, 2019 | 39 | 2019 |
| Fine epitope mapping of the CD19 extracellular domain promotes design JR Klesmith, L Wu, RR Lobb, PD Rennert, BJ Hackel Biochemistry, 2019 | 38 | 2019 |
| An automated data-driven pipeline for improving heterologous enzyme expression EE Wrenbeck, MA Bedewitz, JR Klesmith, S Noshin, CS Barry, ... ACS synthetic biology 8 (3), 474-481, 2019 | 34 | 2019 |
| Producing Glucose 6-Phosphate from Cellulosic Biomass STRUCTURAL INSIGHTS INTO LEVOGLUCOSAN BIOCONVERSION JP Bacik, JR Klesmith, TA Whitehead, LR Jarboe, CJ Unkefer, BL Mark, ... Journal of Biological Chemistry 290 (44), 26638-26648, 2015 | 22 | 2015 |
| Fine epitope mapping of two antibodies neutralizing the Bordetella adenylate cyclase toxin X Wang, JA Stapleton, JR Klesmith, EL Hewlett, TA Whitehead, ... Biochemistry, 2017 | 21 | 2017 |
| Improved mutant function prediction via PACT: Protein Analysis and Classifier Toolkit JR Klesmith, BJ Hackel Bioinformatics 35 (16), 2707–2712, 2018 | 20 | 2018 |
| High-throughput evaluation of synthetic metabolic pathways JR Klesmith, TA Whitehead TECHNOLOGY, 1640001, 2015 | 2 | 2015 |
| Evaluation of enzyme function via high-throughput sequence to function mapping JR Klesmith Michigan State University, 2016 | 1 | 2016 |
| Methods for generating single-or multi-site mutagenesis J Klesmith, J Stapleton, T Whitehead, E Wrenbeck US Patent 11,155,811, 2021 | | 2021 |
| Cd19 variants R Lobb, P Rennert, B Hackel, J Klesmith US Patent App. 16/954,002, 2021 | | 2021 |
| SI DeepSeqData for Fine Epitope Mapping of the CD19 Extracellular Domain Promotes Design JR Klesmith, BJ Hackel https://doi.org/10.6084/m9.figshare.8298161.v1, 2019 | | 2019 |
| CD19 VARIANTS R LOBB, P RENNERT, B HACKEL, J KLESMITH WO Patent App. WO2019118918A1, 2019 | | 2019 |
| SI DeepSeqData for Retargeting CD19 CAR T cells via engineered CD19-fusion proteins JR Klesmith, BJ Hackel https://doi.org/10.6084/m9.figshare.8291759.v1, 2019 | | 2019 |
| Redirected CAR T activity via CD19-ligand fusions engineered by deep mutational scanning J Klesmith, B Hackel ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
| Comprehensive evaluation of protein sequence-function landscapes using deep sequencing JR Klesmith, EE Wrenbeck, CA Kowalsky, TA Whitehead PROTEIN SCIENCE 25, 73-73, 2016 | | 2016 |
Emily E. WrenbeckGinkgo Bioworks, Boston, MA在 ginkgobioworks.com 的电子邮件经过验证
