Direct conversion of normal and Alzheimer’s disease human fibroblasts into neuronal cells by small molecules W Hu, B Qiu, W Guan, Q Wang, M Wang, W Li, L Gao, L Shen, Y Huang, ... Cell stem cell 17 (2), 204-212, 2015 | 498 | 2015 |
Generation of neural progenitor cells by chemical cocktails and hypoxia L Cheng, W Hu, B Qiu, J Zhao, Y Yu, W Guan, M Wang, W Yang, G Pei Cell research 24 (6), 665-679, 2014 | 267 | 2014 |
Diet-induced circadian enhancer remodeling synchronizes opposing hepatic lipid metabolic processes D Guan, Y Xiong, PC Borck, C Jang, PT Doulias, R Papazyan, B Fang, ... Cell 174 (4), 831-842. e12, 2018 | 158 | 2018 |
The hepatocyte clock and feeding control chronophysiology of multiple liver cell types D Guan, Y Xiong, TM Trinh, Y Xiao, W Hu, C Jiang, P Dierickx, C Jang, ... Science 369 (6509), 1388-1394, 2020 | 112 | 2020 |
Direct conversion of astrocytes into neuronal cells by drug cocktail L Cheng, L Gao, W Guan, J Mao, W Hu, B Qiu, J Zhao, Y Yu, G Pei Cell research 25 (11), 1269-1272, 2015 | 95 | 2015 |
β-Arrestin1 regulates zebrafish hematopoiesis through binding to YY1 and relieving polycomb group repression R Yue, J Kang, C Zhao, W Hu, Y Tang, X Liu, G Pei Cell 139 (3), 535-546, 2009 | 52 | 2009 |
Activation of aryl hydrocarbon receptor (ahr) by tranilast, an anti-allergy drug, promotes miR-302 expression and cell reprogramming W Hu, J Zhao, G Pei Journal of Biological Chemistry 288 (32), 22972-22984, 2013 | 49 | 2013 |
Modelling metabolic diseases and drug response using stem cells and organoids W Hu, MA Lazar Nature Reviews Endocrinology 18 (12), 744-759, 2022 | 47 | 2022 |
Natural human genetic variation determines basal and inducible expression of PM20D1, an obesity-associated gene KK Benson, W Hu, AH Weller, AH Bennett, ER Chen, SA Khetarpal, ... Proceedings of the National Academy of Sciences 116 (46), 23232-23242, 2019 | 38 | 2019 |
β-Arrestin-1 protein represses diet-induced obesity L Zhuang, W Hu, M Zhang, S Xin, W Jia, J Zhao, G Pei Journal of Biological Chemistry 286 (32), 28396-28402, 2011 | 38 | 2011 |
Fear erasure facilitated by immature inhibitory neuron transplantation WZ Yang, TT Liu, JW Cao, XF Chen, X Liu, M Wang, X Su, SQ Zhang, ... Neuron 92 (6), 1352-1367, 2016 | 35 | 2016 |
β-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-γ (PPARγ) L Zhuang, W Hu, S Xin, J Zhao, G Pei Journal of Biological Chemistry 286 (32), 28403-28413, 2011 | 35 | 2011 |
Patient adipose stem cell-derived adipocytes reveal genetic variation that predicts antidiabetic drug response W Hu, C Jiang, D Guan, P Dierickx, R Zhang, A Moscati, GN Nadkarni, ... Cell Stem Cell 24 (2), 299-308. e6, 2019 | 30 | 2019 |
Isoform-specific functions of PPARγ in gene regulation and metabolism W Hu, C Jiang, M Kim, Y Xiao, HJ Richter, D Guan, K Zhu, BM Krusen, ... Genes & Development 36 (5-6), 300-312, 2022 | 22 | 2022 |
Individual-specific functional epigenomics reveals genetic determinants of adverse metabolic effects of glucocorticoids W Hu, C Jiang, M Kim, W Yang, K Zhu, D Guan, W Lv, Y Xiao, JR Wilson, ... Cell metabolism 33 (8), 1592-1609. e7, 2021 | 18 | 2021 |
Hepatocytes demarcated by EphB2 contribute to the progression of nonalcoholic steatohepatitis Y Xiao, K Batmanov, W Hu, K Zhu, AY Tom, D Guan, C Jiang, L Cheng, ... Science translational medicine 15 (682), eadc9653, 2023 | 15 | 2023 |
An intrinsically disordered region controlling condensation of a circadian clock component and rhythmic transcription in the liver K Zhu, IJ Celwyn, D Guan, Y Xiao, X Wang, W Hu, C Jiang, L Cheng, ... Molecular cell 83 (19), 3457-3469. e7, 2023 | 9 | 2023 |
Hepatocyte SREBP signaling mediates clock communication within the liver D Guan, H Bae, D Zhou, Y Chen, C Jiang, CM La, Y Xiao, K Zhu, W Hu, ... The Journal of Clinical Investigation 133 (8), 2023 | 5 | 2023 |
Molecular and cellular regulation of thermogenic fat C Wang, X Wang, W Hu Frontiers in Endocrinology 14, 1215772, 2023 | 4 | 2023 |
Novel insights into the pathophysiology of diabetes-related complications: Implications for improved therapeutic strategies J Ma, C Jiang, X Fu, J Chen, W Hu, L Yuan Frontiers in Endocrinology 14, 1157807, 2023 | 1 | 2023 |