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Christian Siebold
Christian Siebold
Professor of Structural Biology
在 strubi.ox.ac.uk 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
MHC class II proteins and disease: a structural perspective
EY Jones, L Fugger, JL Strominger, C Siebold
Nature Reviews Immunology 6 (4), 271-282, 2006
5442006
Mutations in α-tubulin cause abnormal neuronal migration in mice and lissencephaly in humans
DA Keays, G Tian, K Poirier, GJ Huang, C Siebold, J Cleak, PL Oliver, ...
Cell 128 (1), 45-57, 2007
4812007
Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension
CH Coles, Y Shen, AP Tenney, C Siebold, GC Sutton, W Lu, JT Gallagher, ...
Science 332 (6028), 484-488, 2011
3652011
Structural basis of Smoothened regulation by its extracellular domains
EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ...
Nature 535 (7613), 517-522, 2016
3542016
Initiation of T cell signaling by CD45 segregation at'close contacts'
VT Chang, RA Fernandes, KA Ganzinger, SF Lee, C Siebold, J McColl, ...
Nature immunology 17 (5), 574-582, 2016
3122016
A procedure for setting up high-throughput nanolitre crystallization experiments. Crystallization workflow for initial screening, automated storage, imaging and optimization
TS Walter, JM Diprose, CJ Mayo, C Siebold, MG Pickford, L Carter, ...
Acta Crystallographica Section D: Biological Crystallography 61 (6), 651-657, 2005
2852005
Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A)
K Poirier, DA Keays, F Francis, Y Saillour, N Bahi, S Manouvrier, ...
Human mutation 28 (11), 1055-1064, 2007
2752007
Structural basis of semaphorin–plexin signalling
BJC Janssen, RA Robinson, F Pérez-Brangulí, CH Bell, KJ Mitchell, ...
Nature 467 (7319), 1118-1122, 2010
2722010
Interactions between Hedgehog proteins and their binding partners come into view
PA Beachy, SG Hymowitz, RA Lazarus, DJ Leahy, C Siebold
Genes & development 24 (18), 2001-2012, 2010
2672010
Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling
G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ...
Elife 5, e20304, 2016
2292016
Biochemical mechanisms of vertebrate hedgehog signaling
JH Kong, C Siebold, R Rohatgi
Development 146 (10), dev166892, 2019
2212019
Structure of the fungal β‐glucan‐binding immune receptor dectin‐1: Implications for function
J Brown, CA O'Callaghan, ASJ Marshall, RJC Gilbert, C Siebold, ...
Protein Science 16 (6), 1042-1052, 2007
2062007
Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex
BJC Janssen, T Malinauskas, GA Weir, MZ Cader, C Siebold, EY Jones
Nature structural & molecular biology 19 (12), 1293-1299, 2012
2032012
Restoring p53 function in human melanoma cells by inhibiting MDM2 and cyclin B1/CDK1-phosphorylated nuclear iASPP
M Lu, H Breyssens, V Salter, S Zhong, Y Hu, C Baer, I Ratnayaka, ...
Cancer cell 23 (5), 618-633, 2013
1972013
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy
C Siebold, BE Hansen, JR Wyer, K Harlos, RE Esnouf, A Svejgaard, ...
Proceedings of the National Academy of Sciences 101 (7), 1999-2004, 2004
1872004
Structure and function of the Smoothened extracellular domain in vertebrate Hedgehog signaling
S Nachtergaele, DM Whalen, LK Mydock, Z Zhao, T Malinauskas, ...
elife 2, e01340, 2013
1802013
Lentiviral transduction of mammalian cells for fast, scalable and high-level production of soluble and membrane proteins
J Elegheert, E Behiels, B Bishop, S Scott, RE Woolley, SC Griffiths, ...
Nature protocols 13 (12), 2991-3017, 2018
1782018
Modular mechanism of Wnt signaling inhibition by Wnt inhibitory factor 1
T Malinauskas, AR Aricescu, W Lu, C Siebold, EY Jones
Nature structural & molecular biology 18 (8), 886-893, 2011
1732011
Carbohydrate transporters of the bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS)
C Siebold, K Flükiger, R Beutler, B Erni
FEBS letters 504 (3), 104-111, 2001
1602001
Structural insights into hedgehog ligand sequestration by the human hedgehog-interacting protein HHIP
B Bishop, AR Aricescu, K Harlos, CA O'callaghan, EY Jones, C Siebold
Nature structural & molecular biology 16 (7), 698-703, 2009
1522009
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