| Persistent complement dysregulation with signs of thromboinflammation in active Long Covid C Cervia-Hasler, SC Brüningk, T Hoch, B Fan, G Muzio, RC Thompson, ... Science 383 (6680), eadg7942, 2024 | 183 | 2024 |
| Dehydroalanine-based diubiquitin activity probes N Haj-Yahya, HP Hemantha, R Meledin, S Bondalapati, M Seenaiah, ... Organic letters 16 (2), 540-543, 2014 | 106 | 2014 |
| Palladium‐Mediated Cleavage of Proteins with Thiazolidine‐Modified Backbone in Live Cells G Mann, G Satish, R Meledin, GB Vamisetti, A Brik Angewandte chemie 131 (38), 13674-13683, 2019 | 67 | 2019 |
| Diverse fate of ubiquitin chain moieties: the proximal is degraded with the target, and the distal protects the proximal from removal and recycles H Sun, SM Mali, SK Singh, R Meledin, A Brik, YT Kwon, ... Proceedings of the National Academy of Sciences 116 (16), 7805-7812, 2019 | 56 | 2019 |
| Protein ubiquitination via dehydroalanine: development and insights into the diastereoselective 1, 4-addition step R Meledin, SM Mali, SK Singh, A Brik Organic & biomolecular chemistry 14 (21), 4817-4823, 2016 | 56 | 2016 |
| Activity‐Based Probes Developed by Applying a Sequential Dehydroalanine Formation Strategy to Expressed Proteins Reveal a Potential α‐Globin‐Modulating Deubiquitinase R Meledin, SM Mali, O Kleifeld, A Brik Angewandte Chemie 130 (20), 5747-5751, 2018 | 48 | 2018 |
| Total chemical synthesis of ester-linked ubiquitinated proteins unravels their behavior with deubiquitinases H Sun, R Meledin, SM Mali, A Brik Chemical science 9 (6), 1661-1665, 2018 | 24 | 2018 |
| Pushing the boundaries of chemical protein synthesis: the case of ubiquitin chains and polyubiquitinated peptides and proteins R Meledin, SM Mali, A Brik The Chemical Record 16 (1), 509-519, 2016 | 15 | 2016 |
| The Development of a Fluorescence‐Based Competitive Assay Enabled the Discovery of Dimeric Cyclic Peptide Modulators of Ubiquitin Chains GB Vamisetti, R Meledin, M Nawatha, H Suga, A Brik Angewandte Chemie 133 (13), 7094-7099, 2021 | 9 | 2021 |
| Halogen substituents in the isoquinoline scaffold switches the selectivity of inhibition between USP2 and USP7 GB Vamisetti, R Meledin, P Gopinath, A Brik ChemBioChem 20 (2), 282-286, 2019 | 9 | 2019 |
| Examining the role of phosphorylation of p19 INK4d in its stability and ubiquitination using chemical protein synthesis M Msallam, H Sun, R Meledin, P Franz, A Brik Chemical Science 11 (21), 5526-5531, 2020 | 8 | 2020 |
| Dissecting the roles of the N-and C-flanking residues of acetyllysine substrates for SIRT1 activity. R Meledin, A Brik, A Aharoni Chembiochem: a European Journal of Chemical Biology 14 (5), 577-581, 2013 | 8 | 2013 |
| Mirroring Life’s Building Blocks R Meledin, A Brik Cell Chemical Biology 26 (5), 616-619, 2019 | 2 | 2019 |
| Ubiquitin high affinity peptides, and methods of using same, and identifying same A Brik, R Meledin, GB Vamisetti US Patent App. 18/008,515, 2023 | | 2023 |
