Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 338 | 2017 |
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress A Wilmes, A Limonciel, L Aschauer, K Moenks, C Bielow, MO Leonard, ... Journal of proteomics 79, 180-194, 2013 | 195 | 2013 |
An overview of transcriptional regulation in response to toxicological insult P Jennings, A Limonciel, L Felice, MO Leonard Archives of toxicology 87, 49-72, 2013 | 162 | 2013 |
Mechanism of cisplatin proximal tubule toxicity revealed by integrating transcriptomics, proteomics, metabolomics and biokinetics A Wilmes, C Bielow, C Ranninger, P Bellwon, L Aschauer, A Limonciel, ... Toxicology in Vitro 30 (1), 117-127, 2015 | 141 | 2015 |
A review of the evidence that ochratoxin A is an Nrf2 inhibitor: implications for nephrotoxicity and renal carcinogenicity A Limonciel, P Jennings Toxins 6 (1), 371-379, 2014 | 136 | 2014 |
Lactate is an ideal non-invasive marker for evaluating temporal alterations in cell stress and toxicity in repeat dose testing regimes A Limonciel, L Aschauer, A Wilmes, S Prajczer, MO Leonard, W Pfaller, ... Toxicology in Vitro 25 (8), 1855-1862, 2011 | 93 | 2011 |
Delineation of the key aspects in the regulation of epithelial monolayer formation L Aschauer, LN Gruber, W Pfaller, A Limonciel, TJ Athersuch, R Cavill, ... Molecular and cellular biology 33 (13), 2535-2550, 2013 | 91 | 2013 |
Application of RPTEC/TERT1 cells for investigation of repeat dose nephrotoxicity: a transcriptomic study L Aschauer, A Limonciel, A Wilmes, S Stanzel, A Kopp-Schneider, ... Toxicology in Vitro 30 (1), 106-116, 2015 | 68 | 2015 |
Transcriptomic alterations induced by Ochratoxin A in rat and human renal proximal tubular in vitro models and comparison to a rat in vivo model P Jennings, C Weiland, A Limonciel, KM Bloch, R Radford, L Aschauer, ... Archives of toxicology 86, 571-589, 2012 | 55 | 2012 |
Comparison of base-line and chemical-induced transcriptomic responses in HepaRG and RPTEC/TERT1 cells using TempO-Seq A Limonciel, G Ates, G Carta, A Wilmes, M Watzele, PJ Shepard, ... Archives of toxicology 92, 2517-2531, 2018 | 54 | 2018 |
Oxidative stress induced by potassium bromate exposure results in altered tight junction protein expression in renal proximal tubule cells A Limonciel, A Wilmes, L Aschauer, R Radford, KM Bloch, T McMorrow, ... Archives of toxicology 86, 1741-1751, 2012 | 53 | 2012 |
Application of three approaches for quantitative AOP development to renal toxicity E Zgheib, W Gao, A Limonciel, H Aladjov, H Yang, C Tebby, G Gayraud, ... Computational Toxicology 11, 1-13, 2019 | 50 | 2019 |
Development of an in vitro renal epithelial disease state model for xenobiotic toxicity testing D Crean, P Bellwon, L Aschauer, A Limonciel, K Moenks, P Hewitt, ... Toxicology in Vitro 30 (1), 128-137, 2015 | 44 | 2015 |
The EU-ToxRisk method documentation, data processing and chemical testing pipeline for the regulatory use of new approach methods A Krebs, BMA van Vugt-Lussenburg, T Waldmann, W Albrecht, J Boei, ... Archives of Toxicology 94, 2435-2461, 2020 | 41 | 2020 |
Transcriptomics hit the target: Monitoring of ligand-activated and stress response pathways for chemical testing A Limonciel, K Moenks, S Stanzel, GL Truisi, C Parmentier, L Aschauer, ... Toxicology in Vitro 30 (1), 7-18, 2015 | 38 | 2015 |
Evidence for a role of claudin 2 as a proximal tubular stress responsive paracellular water channel A Wilmes, L Aschauer, A Limonciel, W Pfaller, P Jennings Toxicology and applied pharmacology 279 (2), 163-172, 2014 | 38 | 2014 |
Interleukin-19 as a translational indicator of renal injury P Jennings, D Crean, L Aschauer, A Limonciel, K Moenks, G Kern, ... Archives of toxicology 89, 101-106, 2015 | 31 | 2015 |
Investigation of Nrf2, AhR and ATF4 activation in toxicogenomic databases E Zgheib, A Limonciel, X Jiang, A Wilmes, S Wink, B Van de Water, ... Frontiers in genetics 9, 429, 2018 | 28 | 2018 |
Improving global feature detectabilities through scan range splitting for untargeted metabolomics by high-performance liquid chromatography-Orbitrap mass spectrometry C Ranninger, LE Schmidt, M Rurik, A Limonciel, P Jennings, ... Analytica chimica acta 930, 13-22, 2016 | 27 | 2016 |
Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action SE Escher, A Aguayo-Orozco, E Benfenati, A Bitsch, T Braunbeck, ... Toxicology in Vitro 79, 105269, 2022 | 19 | 2022 |