New gene functions in megakaryopoiesis and platelet formation C Gieger, A Radhakrishnan, A Cvejic, W Tang, E Porcu, G Pistis, ... Nature 480 (7376), 201-208, 2011 | 489 | 2011 |
Seventy-five genetic loci influencing the human red blood cell P Van Der Harst, W Zhang, I Mateo Leach, A Rendon, N Verweij, J Sehmi, ... Nature 492 (7429), 369-375, 2012 | 390 | 2012 |
The histone chaperone CAF-1 safeguards somatic cell identity S Cheloufi, U Elling, B Hopfgartner, YL Jung, J Murn, M Ninova, ... Nature 528 (7581), 218-224, 2015 | 287 | 2015 |
Forward and reverse genetics through derivation of haploid mouse embryonic stem cells U Elling, J Taubenschmid, G Wirnsberger, R O'Malley, SP Demers, ... Cell stem cell 9 (6), 563-574, 2011 | 279 | 2011 |
A global in vivo Drosophila RNAi screen identifies NOT3 as a conserved regulator of heart function GG Neely, K Kuba, A Cammarato, K Isobe, S Amann, L Zhang, M Murata, ... Cell 141 (1), 142-153, 2010 | 245 | 2010 |
Murine inner cell mass-derived lineages depend on Sall4 function U Elling, C Klasen, T Eisenberger, K Anlag, M Treier Proceedings of the National Academy of Sciences 103 (44), 16319-16324, 2006 | 225 | 2006 |
JAGN1 deficiency causes aberrant myeloid cell homeostasis and congenital neutropenia K Boztug, PM Järvinen, E Salzer, T Racek, S Mönch, W Garncarz, ... Nature genetics 46 (9), 1021-1027, 2014 | 140 | 2014 |
Comparative glycoproteomics of stem cells identifies new players in ricin toxicity J Stadlmann, J Taubenschmid, D Wenzel, A Gattinger, G Dürnberger, ... Nature 549 (7673), 538-542, 2017 | 125 | 2017 |
A human tissue screen identifies a regulator of ER secretion as a brain-size determinant C Esk, D Lindenhofer, S Haendeler, RA Wester, F Pflug, B Schroeder, ... Science 370 (6519), 935-941, 2020 | 124 | 2020 |
The stress kinase MKK7 couples oncogenic stress to p53 stability and tumor suppression D Schramek, A Kotsinas, A Meixner, T Wada, U Elling, JA Pospisilik, ... Nature genetics 43 (3), 212-219, 2011 | 117 | 2011 |
CRISPR-UMI: single-cell lineage tracing of pooled CRISPR–Cas9 screens G Michlits, M Hubmann, SH Wu, G Vainorius, E Budusan, S Zhuk, ... Nature methods 14 (12), 1191-1197, 2017 | 110 | 2017 |
Multilayered VBC score predicts sgRNAs that efficiently generate loss-of-function alleles G Michlits, J Jude, M Hinterndorfer, M de Almeida, G Vainorius, ... Nature Methods 17 (7), 708-716, 2020 | 91 | 2020 |
Roles of the Homothorax/Meis/Prep homolog UNC-62 and the Exd/Pbx homologs CEH-20 and CEH-40 in C. elegans embryogenesis K Van Auken, D Weaver, B Robertson, M Sundaram, T Saldi, L Edgar, ... Oxford University Press for The Company of Biologists Limited 129 (22), 5255 …, 2002 | 87 | 2002 |
DUSP9 modulates DNA hypomethylation in female mouse pluripotent stem cells J Choi, K Clement, AJ Huebner, J Webster, CM Rose, J Brumbaugh, ... Cell stem cell 20 (5), 706-719. e7, 2017 | 79 | 2017 |
Canonical PRC1 controls sequence-independent propagation of Polycomb-mediated gene silencing HF Moussa, D Bsteh, R Yelagandula, C Pribitzer, K Stecher, K Bartalska, ... Nature communications 10 (1), 1931, 2019 | 78 | 2019 |
The novel lncRNA lnc-NR2F1 is pro-neurogenic and mutated in human neurodevelopmental disorders CE Ang, Q Ma, OL Wapinski, SH Fan, RA Flynn, QY Lee, B Coe, ... Elife 8, e41770, 2019 | 72 | 2019 |
Neutralizing Gatad2a-Chd4-Mbd3/NuRD complex facilitates deterministic induction of naive pluripotency N Mor, Y Rais, D Sheban, S Peles, A Aguilera-Castrejon, A Zviran, ... Cell stem cell 23 (3), 412-425. e10, 2018 | 71 | 2018 |
A reversible haploid mouse embryonic stem cell biobank resource for functional genomics U Elling, RA Wimmer, A Leibbrandt, T Burkard, G Michlits, A Leopoldi, ... Nature 550 (7674), 114-118, 2017 | 67 | 2017 |
Single-cell brain organoid screening identifies developmental defects in autism C Li, JS Fleck, C Martins-Costa, TR Burkard, J Themann, M Stuempflen, ... Nature 621 (7978), 373-380, 2023 | 64 | 2023 |
Jagunal homolog 1 is a critical regulator of neutrophil function in fungal host defense G Wirnsberger, F Zwolanek, J Stadlmann, L Tortola, SW Liu, T Perlot, ... Nature genetics 46 (9), 1028-1033, 2014 | 61 | 2014 |