A simple and very efficient method for generating cDNA libraries U Gubler, BJ Hoffman Gene 25 (2-3), 263-269, 1983 | 5562 | 1983 |
The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses MK Gately, LM Renzetti, J Magram, AS Stern, L Adorini, U Gubler, ... Annual review of immunology 16 (1), 495-521, 1998 | 1653 | 1998 |
Regulation of the interleukin (IL)-12R β2 subunit expression in developing T helper 1 (Th1) and Th2 cells SJ Szabo, AS Dighe, U Gubler, KM Murphy The Journal of experimental medicine 185 (5), 817-824, 1997 | 1350 | 1997 |
Cloning and expression of murine interleukin-1 cDNA in Escherichia coli PT Lomedico, U Gubler, CP Hellmann, M Dukovich, JG Giri, YCE Pan, ... Nature 312 (5993), 458-462, 1984 | 1066 | 1984 |
Selective expression of an interleukin-12 receptor component by human T helper 1 cells L Rogge, L Barberis-Maino, M Biffi, N Passini, DH Presky, U Gubler, ... The Journal of experimental medicine 185 (5), 825-832, 1997 | 944 | 1997 |
A functional interleukin 12 receptor complex is composed of two β-type cytokine receptor subunits DH Presky, H Yang, LJ Minetti, AO Chua, N Nabavi, CY Wu, MK Gately, ... Proceedings of the National Academy of Sciences 93 (24), 14002-14007, 1996 | 910 | 1996 |
Coexpression of two distinct genes is required to generate secreted bioactive cytotoxic lymphocyte maturation factor. U Gubler, AO Chua, DS Schoenhaut, CM Dwyer, W McComas, R Motyka, ... Proceedings of the National Academy of Sciences 88 (10), 4143-4147, 1991 | 857 | 1991 |
Molecular cloning establishes proenkephalin as precursor of enkephalin-containing peptides U Gubler, P Seeburg, BJ Hoffman, LP Gage, S Udenfriend Nature 295 (5846), 206-208, 1982 | 737 | 1982 |
Cloning and expression of murine IL-12. DS Schoenhaut, AO Chua, AG Wolitzky, PM Quinn, CM Dwyer, ... Journal of immunology (Baltimore, Md.: 1950) 148 (11), 3433-3440, 1992 | 613 | 1992 |
Regulation of human lymphocyte proliferation by a heterodimeric cytokine, IL-12 (cytotoxic lymphocyte maturation factor). MK Gately, BB Desai, AG Wolitzky, PM Quinn, CM Dwyer, FJ Podlaski, ... Journal of immunology (Baltimore, Md.: 1950) 147 (3), 874-882, 1991 | 612 | 1991 |
Mouse interleukin‐12 (IL‐12) p40 homodimer: a potent IL‐12 antagonist S Gillessen, D Carvajal, P Ling, FJ Podlaski, DL Stremlo, PC Familletti, ... European journal of immunology 25 (1), 200-206, 1995 | 589 | 1995 |
Human IL-12 p40 homodimer binds to the IL-12 receptor but does not mediate biologic activity. P Ling, MK Gately, U Gubler, AS Stern, P Lin, K Hollfelder, C Su, YC Pan, ... Journal of immunology (Baltimore, Md.: 1950) 154 (1), 116-127, 1995 | 538 | 1995 |
Developmental commitment to the Th2 lineage by extinction of IL-12 signaling SJ Szabo, NG Jacobson, AS Dighe, U Gubler, KM Murphy Immunity 2 (6), 665-675, 1995 | 510 | 1995 |
Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical … TS Kupper, DW Ballard, AO Chua, JS McGuire, PM Flood, MC Horowitz, ... The Journal of experimental medicine 164 (6), 2095-2100, 1986 | 479 | 1986 |
Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation. TS Kupper, AO Chua, P Flood, J McGuire, U Gubler The Journal of clinical investigation 80 (2), 430-436, 1987 | 440 | 1987 |
Fibroblasts Genetically Engineered to Secrete Interleukin 12 Can Suppress Tumor Growth and Induce Antitumor Immunity to a Murine Melanoma in Vivo H Tahara, HJ Zeh III, WJ Storkus, I Pappo, SC Watkins, U Gubler, SF Wolf, ... Cancer research 54 (1), 182-189, 1994 | 394 | 1994 |
Two human TNF receptors have similar extracellular, but distinct intracellular, domain sequences Z Dembic, H Loetscher, U Gubler, YCE Pan, HW Lahm, R Gentz, ... Cytokine 2 (4), 231-237, 1990 | 353 | 1990 |
Two high-affinity interleukin 1 receptors represent separate gene products. R Chizzonite, T Truitt, PL Kilian, AS Stern, P Nunes, KP Parker, KL Kaffka, ... Proceedings of the National Academy of Sciences 86 (20), 8029-8033, 1989 | 352 | 1989 |
Effective eradication of established murine tumors with IL-12 gene therapy using a polycistronic retroviral vector. H Tahara, L Zitvogel, WJ Storkus, HJ Zeh 3rd, TG McKinney, ... Journal of immunology (Baltimore, Md.: 1950) 154 (12), 6466-6474, 1995 | 325 | 1995 |
Interleukin 1 alpha and interleukin 1 beta bind to the same receptor on T cells. PL Kilian, KL Kaffka, AS Stern, D Woehle, WR Benjamin, TM Dechiara, ... Journal of immunology (Baltimore, Md.: 1950) 136 (12), 4509-4514, 1986 | 319 | 1986 |