Structural basis for activation of the titin kinase domain during myofibrillogenesis O Mayans, PFM van der Ven, M Wilm, A Mues, P Young, DO Fürst, ... Nature 395 (6705), 863-869, 1998 | 479 | 1998 |
Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate … O Mayans, M Scott, I Connerton, T Gravesen, J Benen, J Visser, ... Structure 5 (5), 677-689, 1997 | 259 | 1997 |
Palindromic assembly of the giant muscle protein titin in the sarcomeric Z-disk P Zou, N Pinotsis, S Lange, YH Song, A Popov, I Mavridis, OM Mayans, ... Nature 439 (7073), 229-233, 2006 | 222 | 2006 |
Structure and evolution of parallel β-helix proteins J Jenkins, O Mayans, R Pickersgill Journal of structural biology 122 (1-2), 236-246, 1998 | 163 | 1998 |
Differential regulation of a hyperthermophilic α-amylase with a novel (Ca, Zn) two-metal center by zinc A Linden, O Mayans, W Meyer-Klaucke, G Antranikian, M Wilmanns Journal of Biological Chemistry 278 (11), 9875-9884, 2003 | 154 | 2003 |
Three-dimensional structure of Erwinia chrysanthemi pectin methylesterase reveals a novel esterase active site J Jenkins, O Mayans, D Smith, K Worboys, RW Pickersgill Journal of molecular biology 305 (4), 951-960, 2001 | 140 | 2001 |
AMPLE: a cluster-and-truncate approach to solve the crystal structures of small proteins using rapidly computed ab initio models J Bibby, RM Keegan, O Mayans, MD Winn, DJ Rigden Acta Crystallographica Section D: Biological Crystallography 68 (12), 1622-1631, 2012 | 136 | 2012 |
Metabolic and target-site mechanisms combine to confer strong DDT resistance in Anopheles gambiae SN Mitchell, DJ Rigden, AJ Dowd, F Lu, CS Wilding, D Weetman, ... PLoS One 9 (3), e92662, 2014 | 135 | 2014 |
Molecular determinants for the recruitment of the ubiquitin-ligase MuRF-1 onto M-line titin M Mrosek, D Labeit, S Witt, H Heerklotz, E von Castelmur, S Labeit, ... The FASEB Journal 21 (7), 1383-1392, 2007 | 118 | 2007 |
Topography for independent binding of α-helical and PPII-helical ligands to a peroxisomal SH3 domain A Douangamath, FV Filipp, ATJ Klein, P Barnett, P Zou, T Voorn-Brouwer, ... Molecular cell 10 (5), 1007-1017, 2002 | 116 | 2002 |
A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain E Von Castelmur, M Marino, DI Svergun, L Kreplak, Z Ucurum-Fotiadis, ... Proceedings of the National Academy of Sciences 105 (4), 1186-1191, 2008 | 108 | 2008 |
Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin O Mayans, J Wuerges, S Canela, M Gautel, M Wilmanns Structure 9 (4), 331-340, 2001 | 100 | 2001 |
Extended glycoprotein structure of the seven domains in human carcinoembryonic antigen by X-ray and neutron solution scattering and an automated curve fitting procedure … MK Boehm, OM Mayans, JD Thornton, RHJ Begent, PA Keep, SJ Perkins Journal of molecular biology 259 (4), 718-736, 1996 | 97 | 1996 |
Widespread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate S Knorr, M Sinn, D Galetskiy, RM Williams, C Wang, N Müller, O Mayans, ... Nature communications 9 (1), 5071, 2018 | 82 | 2018 |
Titin kinase is an inactive pseudokinase scaffold that supports MuRF1 recruitment to the sarcomeric M-line J Bogomolovas, A Gasch, F Simkovic, DJ Rigden, S Labeit, O Mayans Open biology 4 (5), 140041, 2014 | 71 | 2014 |
Secondary and tertiary structure elasticity of titin Z1Z2 and a titin chain model EH Lee, J Hsin, O Mayans, K Schulten Biophysical journal 93 (5), 1719-1735, 2007 | 69 | 2007 |
The Ig doublet Z1Z2: a model system for the hybrid analysis of conformational dynamics in Ig tandems from titin M Marino, P Zou, D Svergun, P Garcia, C Edlich, B Simon, M Wilmanns, ... Structure 14 (9), 1437-1447, 2006 | 63 | 2006 |
Structural Analysis of B-Box 2 from MuRF1: Identification of a Novel Self-Association Pattern in a RING-like Fold†‡ M Mrosek, S Meier, Z Ucurum-Fotiadis, E von Castelmur, E Hedbom, ... Biochemistry 47 (40), 10722-10730, 2008 | 55 | 2008 |
Poly-Ig tandems from I-band titin share extended domain arrangements irrespective of the distinct features of their modular constituents M Marino, DI Svergun, L Kreplak, PV Konarev, B Maco, D Labeit, ... Journal of Muscle Research & Cell Motility 26 (6), 355-365, 2005 | 52 | 2005 |
The structure of the HMG box and its interaction with DNA CM Read, PD Cary, C Crane-Robinson, PC Driscoll, MOM Carrillo, ... Nucleic acids and molecular biology, 222-250, 1995 | 49 | 1995 |