| Sensitive tumour detection and classification using plasma cell-free DNA methylomes SY Shen, R Singhania, G Fehringer, A Chakravarthy, MHA Roehrl, ... Nature 563 (7732), 579-583, 2018 | 726 | 2018 |
| Integrated (epi)-genomic analyses identify subgroup-specific therapeutic targets in CNS rhabdoid tumors J Torchia, B Golbourn, S Feng, KC Ho, P Sin-Chan, A Vasiljevic, ... Cancer cell 30 (6), 891-908, 2016 | 232 | 2016 |
| Apoptotic cell–induced AhR activity is required for immunological tolerance and suppression of systemic lupus erythematosus in mice and humans R Shinde, K Hezaveh, MJ Halaby, A Kloetgen, A Chakravarthy, ... Nature immunology 19 (6), 571-582, 2018 | 157 | 2018 |
| A chemical biology toolbox to study protein methyltransferases and epigenetic signaling S Scheer, S Ackloo, TS Medina, M Schapira, F Li, JA Ward, AM Lewis, ... Nature communications 10 (1), 19, 2019 | 111 | 2019 |
| GCN2 drives macrophage and MDSC function and immunosuppression in the tumor microenvironment MJ Halaby, K Hezaveh, S Lamorte, MT Ciudad, A Kloetgen, BL MacLeod, ... Science immunology 4 (42), eaax8189, 2019 | 107 | 2019 |
| Increased interleukin-10 and interferon-γ levels in Plasmodium vivax malaria suggest a reciprocal regulation which is not altered by IL-10 gene promoter … TS Medina, SPT Costa, MD Oliveira, AM Ventura, JM Souza, TF Gomes, ... Malaria journal 10, 1-10, 2011 | 95 | 2011 |
| B cell orchestration of anti-tumor immune responses: a matter of cell localization and communication GS Kinker, GAF Vitiello, WAS Ferreira, AS Chaves, VC Cordeiro de Lima, ... Frontiers in cell and developmental biology 9, 678127, 2021 | 87 | 2021 |
| DNA hypomethylating agents increase activation and cytolytic activity of CD8+ T cells HL Yau, E Bell, I Ettayebi, FC de Almeida, GM Boukhaled, SY Shen, ... Molecular cell 81 (7), 1469-1483. e8, 2021 | 66 | 2021 |
| The transition from quiescent to activated states in human hematopoietic stem cells is governed by dynamic 3D genome reorganization N Takayama, A Murison, S Takayanagi, C Arlidge, S Zhou, L Garcia-Prat, ... Cell stem cell 28 (3), 488-501. e10, 2021 | 61 | 2021 |
| Development of a Polymerase Chain Reaction (PCR) method based on amplification of mitochondrial DNA to detect Plasmodium falciparum and Plasmodium vivax MG Cunha, TS Medina, SG Oliveira, AN Marinho, MM Póvoa, ... Acta tropica 111 (1), 35-38, 2009 | 56 | 2009 |
| Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities AE Casey, A Sinha, R Singhania, J Livingstone, P Waterhouse, ... Journal of Cell Biology 217 (8), 2951-2974, 2018 | 41 | 2018 |
| Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells E Lima-Fernandes, A Murison, T da Silva Medina, Y Wang, A Ma, ... Nature communications 10 (1), 1436, 2019 | 39 | 2019 |
| Epigenetic regulation of nitric oxide synthase 2, inducible (Nos2) by NLRC4 inflammasomes involves PARP1 cleavage CL Buzzo, T Medina, LM Branco, SL Lage, LCS Ferreira, ... Scientific reports 7 (1), 41686, 2017 | 36 | 2017 |
| Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation S Scheer, TS Medina, A Murison, MD Taves, F Antignano, A Chenery, ... Journal of Leucocyte Biology 101 (4), 893-900, 2017 | 31 | 2017 |
| Mature tertiary lymphoid structures are key niches of tumour-specific immune responses in pancreatic ductal adenocarcinomas GS Kinker, GAF Vitiello, AB Diniz, MP Cabral-Piccin, PHB Pereira, ... Gut 72 (10), 1927-1941, 2023 | 29 | 2023 |
| Antiviral responses in cancer: boosting antitumor immunity through activation of interferon pathway in the tumor microenvironment GAF Vitiello, WAS Ferreira, VC Cordeiro de Lima, TS Medina Frontiers in Immunology 12, 782852, 2021 | 25 | 2021 |
| Canonical PI3Kγ signaling in myeloid cells restricts Trypanosoma cruzi infection and dampens chagasic myocarditis MC Silva, M Davoli-Ferreira, TS Medina, R Sesti-Costa, GK Silva, ... Nature Communications 9 (1), 1513, 2018 | 23 | 2018 |
| Ebi3 Prevents Trypanosoma cruzi-Induced Myocarditis by Dampening IFN-γ-Driven Inflammation TS Medina, GG Oliveira, MC Silva, BA David, GK Silva, DM Fonseca, ... Frontiers in Immunology 8, 1213, 2017 | 22 | 2017 |
| Polymorphic sites at the immunoregulatory CTLA-4 gene are associated with chronic chagas disease and its clinical manifestations FC Dias, TS Medina, CT Mendes-Junior, RO Dantas, CW Pissetti, ... PLoS One 8 (10), e78367, 2013 | 22 | 2013 |
| Chronic Toxoplasma gondii Infection Exacerbates Secondary Polymicrobial Sepsis MC Souza, DM Fonseca, A Kanashiro, L Benevides, TS Medina, MS Dias, ... Frontiers in Cellular and Infection Microbiology 7, 116, 2017 | 14 | 2017 |
