Structure and functions of the GNAT superfamily of acetyltransferases MW Vetting, LPS de Carvalho, M Yu, SS Hegde, S Magnet, SL Roderick, ... Archives of biochemistry and biophysics 433 (1), 212-226, 2005 | 678 | 2005 |
A fluoroquinolone resistance protein from Mycobacterium tuberculosis that mimics DNA SS Hegde, MW Vetting, SL Roderick, LA Mitchenall, A Maxwell, HE Takiff, ... Science 308 (5727), 1480-1483, 2005 | 368 | 2005 |
Pentapeptide repeat proteins MW Vetting, SS Hegde, JE Fajardo, A Fiser, SL Roderick, HE Takiff, ... Biochemistry 45 (1), 1-10, 2006 | 223 | 2006 |
Mycobacterium tuberculosis dihydrofolate reductase is a target for isoniazid A Argyrou, MW Vetting, B Aladegbami, JS Blanchard Nature structural & molecular biology 13 (5), 408-413, 2006 | 182 | 2006 |
Crystallographic comparison of manganese-and iron-dependent homoprotocatechuate 2, 3-dioxygenases MW Vetting, LP Wackett, L Que Jr, JD Lipscomb, DH Ohlendorf Journal of bacteriology 186 (7), 1945-1958, 2004 | 182 | 2004 |
Aminoglycoside 2′-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates MW Vetting, SS Hegde, F Javid-Majd, JS Blanchard, SL Roderick Nature structural biology 9 (9), 653-658, 2002 | 180 | 2002 |
A bacterial acetyltransferase capable of regioselective N-acetylation of antibiotics and histones MW Vetting, S Magnet, E Nieves, SL Roderick, JS Blanchard Chemistry & biology 11 (4), 565-573, 2004 | 173 | 2004 |
Mechanistic and Structural Analysis of Aminoglycoside N-Acetyltransferase AAC(6′)-Ib and Its Bifunctional, Fluoroquinolone-Active AAC(6′)-Ib-cr Variant MW Vetting, CH Park, SS Hegde, GA Jacoby, DC Hooper, JS Blanchard Biochemistry 47 (37), 9825-9835, 2008 | 170 | 2008 |
The 1.8 Å crystal structure of catechol 1, 2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linker MW Vetting, DH Ohlendorf Structure 8 (4), 429-440, 2000 | 169 | 2000 |
Discovery of new enzymes and metabolic pathways by using structure and genome context S Zhao, R Kumar, A Sakai, MW Vetting, BMK Wood, S Brown, ... Nature 502 (7473), 698-702, 2013 | 156 | 2013 |
Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: substrate-assisted catalysis MW Vetting, PA Frantom, JS Blanchard Journal of Biological Chemistry 283 (23), 15834-15844, 2008 | 150 | 2008 |
Structure of QnrB1, a plasmid-mediated fluoroquinolone resistance factor MW Vetting, SS Hegde, M Wang, GA Jacoby, DC Hooper, JS Blanchard Journal of Biological Chemistry 286 (28), 25265-25273, 2011 | 115 | 2011 |
Structure of Acinetobacter strain ADP1 protocatechuate 3, 4-dioxygenase at 2.2 Å resolution: implications for the mechanism of an intradiol dioxygenase MW Vetting, DA D'Argenio, LN Ornston, DH Ohlendorf Biochemistry 39 (27), 7943-7955, 2000 | 114 | 2000 |
Experimental strategies for functional annotation and metabolism discovery: targeted screening of solute binding proteins and unbiased panning of metabolomes MW Vetting, N Al-Obaidi, S Zhao, B San Francisco, J Kim, DJ Wichelecki, ... Biochemistry 54 (3), 909-931, 2015 | 109 | 2015 |
The Active Site of O-Acetylserine Sulfhydrylase Is the Anchor Point for Bienzyme Complex Formation with Serine Acetyltransferase B Huang, MW Vetting, SL Roderick Journal of bacteriology 187 (9), 3201-3205, 2005 | 109 | 2005 |
Large-scale determination of sequence, structure, and function relationships in cytosolic glutathione transferases across the biosphere ST Mashiyama, MM Malabanan, E Akiva, R Bhosle, MC Branch, ... PLoS biology 12 (4), e1001843, 2014 | 102 | 2014 |
Structure of Serine Acetyltransferase in Complexes with CoA and Its Cysteine Feedback Inhibitor, LR Olsen, B Huang, MW Vetting, SL Roderick Biochemistry 43 (20), 6013-6019, 2004 | 102 | 2004 |
Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks S Zhao, A Sakai, X Zhang, MW Vetting, R Kumar, B Hillerich, ... Elife 3, e03275, 2014 | 95 | 2014 |
Crystal structure of RimI from Salmonella typhimurium LT2, the GNAT responsible for Nα‐acetylation of ribosomal protein S18 MW Vetting, DC Bareich, M Yu, JS Blanchard Protein Science 17 (10), 1781-1790, 2008 | 95 | 2008 |
The structure and mechanism of the Mycobacterium tuberculosis cyclodityrosine synthetase MW Vetting, SS Hegde, JS Blanchard Nature chemical biology 6 (11), 797-799, 2010 | 86 | 2010 |