| Accessing protein conformational ensembles using room-temperature X-ray crystallography JS Fraser, H Van Den Bedem, AJ Samelson, PT Lang, JM Holton, ... Proceedings of the National Academy of Sciences 108 (39), 16247-16252, 2011 | 609 | 2011 |
| Integrative, dynamic structural biology at atomic resolution—it's about time H Van Den Bedem, JS Fraser Nature methods 12 (4), 307-318, 2015 | 243 | 2015 |
| Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography DA Keedy, LR Kenner, M Warkentin, RA Woldeyes, JB Hopkins, ... Elife 4, e07574, 2015 | 182 | 2015 |
| Integrated description of protein dynamics from room-temperature X-ray crystallography and NMR RB Fenwick, H van den Bedem, JS Fraser, PE Wright Proceedings of the National Academy of Sciences 111 (4), E445-E454, 2014 | 180 | 2014 |
| Automated identification of functional dynamic contact networks from X-ray crystallography H Van Den Bedem, G Bhabha, K Yang, PE Wright, JS Fraser Nature methods 10 (9), 896-902, 2013 | 148 | 2013 |
| Crystal cryocooling distorts conformational heterogeneity in a model Michaelis complex of DHFR DA Keedy, H Van Den Bedem, DA Sivak, GA Petsko, D Ringe, MA Wilson, ... Structure 22 (6), 899-910, 2014 | 143 | 2014 |
| New paradigm for macromolecular crystallography experiments at SSRL: automated crystal screening and remote data collection SM Soltis, AE Cohen, A Deacon, T Eriksson, A González, S McPhillips, ... Acta Crystallographica Section D: Biological Crystallography 64 (12), 1210-1221, 2008 | 140 | 2008 |
| Automated diffraction image analysis and spot searching for high-throughput crystal screening Z Zhang, NK Sauter, H Van Den Bedem, G Snell, AM Deacon Journal of applied crystallography 39 (1), 112-119, 2006 | 140 | 2006 |
| Modeling discrete heterogeneity in X-ray diffraction data by fitting multi-conformers H Van Den Bedem, A Dhanik, JC Latombe, AM Deacon Acta Crystallographica Section D: Biological Crystallography 65 (10), 1107-1117, 2009 | 122 | 2009 |
| Crystal structures of two novel dye‐decolorizing peroxidases reveal a β‐barrel fold with a conserved heme‐binding motif C Zubieta, SS Krishna, M Kapoor, P Kozbial, D McMullan, HL Axelrod, ... Proteins: Structure, Function, and Bioinformatics 69 (2), 223-233, 2007 | 103 | 2007 |
| Exposing hidden alternative backbone conformations in X-ray crystallography using qFit DA Keedy, JS Fraser, H van den Bedem PLoS computational biology 11 (10), e1004507, 2015 | 90 | 2015 |
| Structural basis of murein peptide specificity of a γ-D-glutamyl-L-diamino acid endopeptidase Q Xu, S Sudek, D McMullan, MD Miller, B Geierstanger, DH Jones, ... Structure 17 (2), 303-313, 2009 | 90 | 2009 |
| Identification and structural characterization of heme binding in a novel dye‐decolorizing peroxidase, TyrA C Zubieta, R Joseph, S Sri Krishna, D McMullan, M Kapoor, HL Axelrod, ... Proteins: Structure, Function, and Bioinformatics 69 (2), 234-243, 2007 | 88 | 2007 |
| Structure of the γ-D-glutamyl-L-diamino acid endopeptidase YkfC from Bacillus cereus in complex with L-Ala-γ-D-Glu: insights into substrate recognition by NlpC/P60 cysteine … Q Xu, P Abdubek, T Astakhova, HL Axelrod, C Bakolitsa, X Cai, D Carlton, ... Acta Crystallographica Section F: Structural Biology and Crystallization …, 2010 | 79 | 2010 |
| Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis M Dasgupta, D Budday, SHP De Oliveira, P Madzelan, ... Proceedings of the National Academy of Sciences 116 (51), 25634-25640, 2019 | 73 | 2019 |
| Crystal structure of thy1, a thymidylate synthase complementing protein from Thermotoga maritima at 2.25 Å resolution P Kuhn, SA Lesley, II Mathews, JM Canaves, LS Brinen, X Dai, ... Proteins: Structure, Function, and Bioinformatics 49 (1), 142-145, 2002 | 73 | 2002 |
| Real-space protein-model completion: an inverse-kinematics approach H Van Den Bedem, I Lotan, JC Latombe, AM Deacon Acta Crystallographica Section D: Biological Crystallography 61 (1), 2-13, 2005 | 71 | 2005 |
| Crystal structure of the global regulatory protein CsrA from Pseudomonas putida at 2.05 Å resolution reveals a new fold C Rife, R Schwarzenbacher, D McMullan, P Abdubek, E Ambing, ... Proteins: Structure, Function, and Bioinformatics 61 (2), 449-453, 2005 | 63 | 2005 |
| Conformational variation of proteins at room temperature is not dominated by radiation damage S Russi, A González, LR Kenner, DA Keedy, JS Fraser, H Bedem Journal of synchrotron radiation 24 (1), 73-82, 2017 | 61 | 2017 |
| Nutrient transport suggests an evolutionary basis for charged archaeal surface layer proteins PN Li, J Herrmann, BB Tolar, F Poitevin, R Ramdasi, JR Bargar, DA Stahl, ... The ISME journal 12 (10), 2389-2402, 2018 | 58 | 2018 |
James S. FraserProfessor, University of California San Francisco在 ucsf.edu 的电子邮件经过验证
