Calmodulin binding and inhibition of cardiac muscle calcium release channel (ryanodine receptor) DM Balshaw, L Xu, N Yamaguchi, DA Pasek, G Meissner Journal of Biological Chemistry 276 (23), 20144-20153, 2001 | 301 | 2001 |
Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants M Stange, L Xu, D Balshaw, N Yamaguchi, G Meissner Journal of Biological Chemistry 278 (51), 51693-51702, 2003 | 209 | 2003 |
Molecular basis of calmodulin binding to cardiac muscle Ca2+ release channel (ryanodine receptor) N Yamaguchi, L Xu, DA Pasek, KE Evans, G Meissner Journal of Biological Chemistry 278 (26), 23480-23486, 2003 | 187 | 2003 |
Early cardiac hypertrophy in mice with impaired calmodulin regulation of cardiac muscle Ca2+ release channel N Yamaguchi, N Takahashi, L Xu, O Smithies, G Meissner The Journal of clinical investigation 117 (5), 1344-1353, 2007 | 152 | 2007 |
Characterization of recessive RYR1 mutations in core myopathies H Zhou, N Yamaguchi, L Xu, Y Wang, C Sewry, H Jungbluth, F Zorzato, ... Human molecular genetics 15 (18), 2791-2803, 2006 | 117 | 2006 |
Identification of apocalmodulin and Ca2+-calmodulin regulatory domain in skeletal muscle Ca2+ release channel, ryanodine receptor N Yamaguchi, C Xin, G Meissner Journal of Biological Chemistry 276 (25), 22579-22585, 2001 | 115 | 2001 |
Modulation of intracellular calcium-release channels by calmodulin DM Balshaw, N Yamaguchi, G Meissner Journal of Membrane Biology 185 (1), 1-8, 2002 | 113 | 2002 |
Mice lacking Homer 1 exhibit a skeletal myopathy characterized by abnormal transient receptor potential channel activity JA Stiber, ZS Zhang, J Burch, JP Eu, S Zhang, GA Truskey, M Seth, ... Molecular and cellular biology 28 (8), 2637-2647, 2008 | 109 | 2008 |
Regulation of the Cardiac Muscle Ryanodine Receptor by O2 Tension and S-Nitrosoglutathione J Sun, N Yamaguchi, L Xu, JP Eu, JS Stamler, G Meissner Biochemistry 47 (52), 13985-13990, 2008 | 106 | 2008 |
Clinical and functional effects of a deletion in a COOH-terminal lumenal loop of the skeletal muscle ryanodine receptor F Zorzato, N Yamaguchi, L Xu, G Meissner, CR Müller, P Pouliquin, ... Human molecular genetics 12 (4), 379-388, 2003 | 54 | 2003 |
Calmodulin regulation and identification of calmodulin binding region of type-3 ryanodine receptor calcium release channel N Yamaguchi, L Xu, DA Pasek, KE Evans, SRW Chen, G Meissner Biochemistry 44 (45), 15074-15081, 2005 | 48 | 2005 |
Single channel properties of heterotetrameric mutant RyR1 ion channels linked to core myopathies L Xu, Y Wang, N Yamaguchi, DA Pasek, G Meissner Journal of Biological Chemistry 283 (10), 6321-6329, 2008 | 47 | 2008 |
Cardiac hypertrophy associated with impaired regulation of cardiac ryanodine receptor by calmodulin and S100A1 N Yamaguchi, A Chakraborty, TQ Huang, L Xu, AC Gomez, DA Pasek, ... American Journal of Physiology-Heart and Circulatory Physiology 305 (1), H86-H94, 2013 | 42 | 2013 |
Cardiac calcium signalling pathologies associated with defective calmodulin regulation of type 2 ryanodine receptor JJ Arnáiz‐Cot, BJ Damon, XH Zhang, L Cleemann, N Yamaguchi, ... The Journal of physiology 591 (17), 4287-4299, 2013 | 40 | 2013 |
Calmodulin binding to the 3614–3643 region of RyR1 is not essential for excitation–contraction coupling in skeletal myotubes KMS O'Connell, N Yamaguchi, G Meissner, RT Dirksen The Journal of general physiology 120 (3), 337-347, 2002 | 39 | 2002 |
Two Regions of the Ryanodine Receptor Calcium Channel Are Involved in Ca2+-Dependent Inactivation AC Gomez, N Yamaguchi Biochemistry 53 (8), 1373-1379, 2014 | 38 | 2014 |
Modulation of sarcoplasmic reticulum Ca2+ release in skeletal muscle expressing ryanodine receptor impaired in regulation by calmodulin and S100A1 N Yamaguchi, BL Prosser, F Ghassemi, L Xu, DA Pasek, JP Eu, ... American Journal of Physiology-Cell Physiology 300 (5), C998-C1012, 2011 | 38 | 2011 |
CRISPR/Cas9 Gene editing of RyR2 in human stem cell-derived cardiomyocytes provides a novel approach in investigating dysfunctional Ca2+ signaling H Wei, XH Zhang, C Clift, N Yamaguchi, M Morad Cell calcium 73, 104-111, 2018 | 30 | 2018 |
Molecular Insights into Calcium Dependent Regulation of Ryanodine Receptor Calcium Release Channels N Yamaguchi Calcium Signaling, 321-336, 2020 | 26 | 2020 |
Ca2+-mediated activation of the skeletal-muscle ryanodine receptor ion channel L Xu, VR Chirasani, JS Carter, DA Pasek, NV Dokholyan, N Yamaguchi, ... Journal of Biological Chemistry 293 (50), 19501-19509, 2018 | 26 | 2018 |