Widespread microRNA repression by Myc contributes to tumorigenesis TC Chang, D Yu, YS Lee, EA Wentzel, DE Arking, KM West, CV Dang, ... Nature genetics 40 (1), 43-50, 2008 | 1688 | 2008 |
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma RK Amaravadi, D Yu, JJ Lum, T Bui, MA Christophorou, GI Evan, ... The Journal of clinical investigation 117 (2), 326-336, 2007 | 1412 | 2007 |
Augmentation of tumor angiogenesis by a Myc-activated microRNA cluster M Dews, A Homayouni, D Yu, D Murphy, C Sevignani, E Wentzel, ... Nature genetics 38 (9), 1060-1065, 2006 | 1324 | 2006 |
Convergence of acquired mutations and alternative splicing of CD19 enables resistance to CART-19 immunotherapy E Sotillo, DM Barrett, KL Black, A Bagashev, D Oldridge, G Wu, ... Cancer discovery 5 (12), 1282-1295, 2015 | 1222 | 2015 |
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation TC Chang, LR Zeitels, HW Hwang, RR Chivukula, EA Wentzel, M Dews, ... Proceedings of the National Academy of Sciences 106 (9), 3384-3389, 2009 | 486 | 2009 |
ER stress–mediated autophagy promotes Myc-dependent transformation and tumor growth LS Hart, JT Cunningham, T Datta, S Dey, F Tameire, SL Lehman, BO Qiu, ... The Journal of clinical investigation 122 (12), 4621-4634, 2012 | 427 | 2012 |
The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ... Molecular cell 40 (5), 762-773, 2010 | 359 | 2010 |
The Myc–miR-17∼ 92 axis blunts TGFβ signaling and production of multiple TGFβ-dependent antiangiogenic factors M Dews, JL Fox, S Hultine, P Sundaram, W Wang, YY Liu, E Furth, ... Cancer research 70 (20), 8233-8246, 2010 | 321 | 2010 |
Direct repression of FLIP expression by c-myc is a major determinant of TRAIL sensitivity MS Ricci, Z Jin, M Dews, D Yu, A Thomas-Tikhonenko, DT Dicker, ... Molecular and cellular biology, 2004 | 305 | 2004 |
Activation of transferrin receptor 1 by c-Myc enhances cellular proliferation and tumorigenesis KA O'Donnell, D Yu, KI Zeller, J Kim, F Racke, A Thomas-Tikhonenko, ... Molecular and cellular biology 26 (6), 2373-2386, 2006 | 285 | 2006 |
p53-responsive miR-194 inhibits thrombospondin-1 and promotes angiogenesis in colon cancers P Sundaram, S Hultine, LM Smith, M Dews, JL Fox, D Biyashev, ... Cancer research 71 (24), 7490-7501, 2011 | 180 | 2011 |
CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy V Pillai, K Muralidharan, W Meng, A Bagashev, DA Oldridge, J Rosenthal, ... Blood advances 3 (22), 3539-3549, 2019 | 168 | 2019 |
B cell–specific loss of histone 3 lysine 9 methylation in the VH locus depends on Pax5 K Johnson, DL Pflugh, D Yu, DGT Hesslein, KI Lin, ALM Bothwell, ... Nature immunology 5 (8), 853-861, 2004 | 143 | 2004 |
Metastasis-associated protein 1 (MTA1) is an essential downstream effector of the c-MYC oncoprotein X Zhang, LM DeSalle, JH Patel, AJ Capobianco, D Yu, ... Proceedings of the National Academy of Sciences 102 (39), 13968-13973, 2005 | 140 | 2005 |
CD19 is a major B cell receptor–independent activator of MYC-driven B-lymphomagenesis EY Chung, JN Psathas, D Yu, Y Li, MJ Weiss, A Thomas-Tikhonenko The Journal of clinical investigation 122 (6), 2257-2266, 2012 | 122 | 2012 |
Oncogenic BRAF regulates β-Trcp expression and NF-κB activity in human melanoma cells J Liu, KG Suresh Kumar, D Yu, SA Molton, M McMahon, M Herlyn, ... Oncogene 26 (13), 1954-1958, 2007 | 121 | 2007 |
Viral Myc oncoproteins in infected fibroblasts down-modulate thrombospondin-1, a possible tumor suppressor gene AT Tikhonenko, DJ Black, ML Linial Journal of Biological Chemistry 271 (48), 30741-30747, 1996 | 121 | 1996 |
Role of GLI2 transcription factor in growth and tumorigenicity of prostate cells S Thiyagarajan, N Bhatia, S Reagan-Shaw, D Cozma, ... Cancer research 67 (22), 10642-10646, 2007 | 112 | 2007 |
Cutting edge: systemic inhibition of angiogenesis underlies resistance to tumors during acute toxoplasmosis CA Hunter, D Yu, M Gee, CV Ngo, C Sevignani, M Goldschmidt, ... The Journal of Immunology 166 (10), 5878-5881, 2001 | 112 | 2001 |
An in Vivo Function for the Transforming Myc Protein: Elicitation of the Angiogenic Phenotype CV Ngo, M Gee, N Akhtar, D Yu, O Volpert, R Auerbach, ... | 111 | 2000 |